Thiostrepton selectively targets breast cancer cells through inhibition of forkhead box M1 expression.
about
FOXM1 confers acquired cisplatin resistance in breast cancer cellsCyclisation mechanisms in the biosynthesis of ribosomally synthesised and post-translationally modified peptidesThe Role of Forkhead Box Protein M1 in Breast Cancer Progression and Resistance to TherapyThiopeptide antibiotics: retrospective and recent advancesFOXM1: an emerging master regulator of DNA damage response and genotoxic agent resistanceDisabling Mitochondrial Peroxide Metabolism via Combinatorial Targeting of Peroxiredoxin 3 as an Effective Therapeutic Approach for Malignant MesotheliomaStructure of the FoxM1 DNA-recognition domain bound to a promoter sequenceInvariom refinement of a new monoclinic solvate of thiostrepton at 0.64 Å resolutionConstitutively nuclear FOXO3a localization predicts poor survival and promotes Akt phosphorylation in breast cancerFOXM1 is an oncogenic mediator in Ewing SarcomaPeroxiredoxin 3 is a redox-dependent target of thiostrepton in malignant mesothelioma cellsSystematic drug perturbations on cancer cells reveal diverse exit paths from proliferative stateSUMOylation inhibits FOXM1 activity and delays mitotic transition.New anti-tuberculosis agents amongst known drugs.FOXO3a represses VEGF expression through FOXM1-dependent and -independent mechanisms in breast cancer.FoxM1, a forkhead transcription factor is a master cell cycle regulator for mouse mature T cells but not double positive thymocytesIdentification of small-molecule inhibitors of ricin and shiga toxin using a cell-based high-throughput screenIdentification of neuron selective androgen receptor inhibitors.Prognostic value of FOXM1 in solid tumors: a systematic review and meta-analysis.FOXM1 recruits nuclear Aurora kinase A to participate in a positive feedback loop essential for the self-renewal of breast cancer stem cells.FOXM1 is a transcriptional target of ERalpha and has a critical role in breast cancer endocrine sensitivity and resistanceDefinition of microRNAs that repress expression of the tumor suppressor gene FOXO1 in endometrial cancer.New potential anti-cancer agents synergize with bortezomib and ABT-737 against prostate cancer.FOXM1 mediates resistance to docetaxel in gastric cancer via up-regulating Stathmin.Aberrant activation of ERK/FOXM1 signaling cascade triggers the cell migration/invasion in ovarian cancer cells.Production of a new thiopeptide antibiotic, TP-1161, by a marine Nocardiopsis species.Down-regulation of FoxM1 by thiostrepton or small interfering RNA inhibits proliferation, transformation ability and angiogenesis, and induces apoptosis of nasopharyngeal carcinoma cells.Overexpression of forkhead box protein M1 (FOXM1) in ovarian cancer correlates with poor patient survival and contributes to paclitaxel resistanceOverexpression of FOXM1 is associated with metastases of nasopharyngeal carcinomaSuppression of the FOXM1 transcriptional programme via novel small molecule inhibitionAntimicrobial activity and probable mechanisms of action of medicinal plants of Kenya: Withania somnifera, Warbugia ugandensis, Prunus africana and Plectrunthus barbatusStructural basis and dynamics of multidrug recognition in a minimal bacterial multidrug resistance system.Resistance to HER2-targeted therapies: a potential role for FOXM1.Targeting of mutant p53-induced FoxM1 with thiostrepton induces cytotoxicity and enhances carboplatin sensitivity in cancer cellsERβ1 represses FOXM1 expression through targeting ERα to control cell proliferation in breast cancer.FOXM1 confers to epithelial-mesenchymal transition, stemness and chemoresistance in epithelial ovarian carcinoma cells.Micelle-encapsulated thiostrepton as an effective nanomedicine for inhibiting tumor growth and for suppressing FOXM1 in human xenografts.Thiostrepton is an inducer of oxidative and proteotoxic stress that impairs viability of human melanoma cells but not primary melanocytesPaclitaxel targets FOXM1 to regulate KIF20A in mitotic catastrophe and breast cancer paclitaxel resistance.MEIS2 is essential for neuroblastoma cell survival and proliferation by transcriptional control of M-phase progression.
P2860
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P2860
Thiostrepton selectively targets breast cancer cells through inhibition of forkhead box M1 expression.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Thiostrepton selectively targe ...... of forkhead box M1 expression.
@ast
Thiostrepton selectively targe ...... of forkhead box M1 expression.
@en
Thiostrepton selectively targe ...... of forkhead box M1 expression.
@nl
type
label
Thiostrepton selectively targe ...... of forkhead box M1 expression.
@ast
Thiostrepton selectively targe ...... of forkhead box M1 expression.
@en
Thiostrepton selectively targe ...... of forkhead box M1 expression.
@nl
prefLabel
Thiostrepton selectively targe ...... of forkhead box M1 expression.
@ast
Thiostrepton selectively targe ...... of forkhead box M1 expression.
@en
Thiostrepton selectively targe ...... of forkhead box M1 expression.
@nl
P2093
P1476
Thiostrepton selectively targe ...... of forkhead box M1 expression.
@en
P2093
Charles M Marson
Demetra Constantinidou
Jimmy M-M Kwok
R Charles Coombes
Stephen S Myatt
P304
P356
10.1158/1535-7163.MCT-08-0188
P50
P577
2008-07-01T00:00:00Z