about
The CK1 Family: Contribution to Cellular Stress Response and Its Role in CarcinogenesisThe p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancersLATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stabilityCyclin G2 is a centrosome-associated nucleocytoplasmic shuttling protein that influences microtubule stability and induces a p53-dependent cell cycle arrestThe de novo centriole assembly pathway in HeLa cells: cell cycle progression and centriole assembly/maturationGenomic Changes in Normal Breast Tissue in Women at Normal Risk or at High Risk for Breast CancerUpdated overview of current biomarkers in head and neck carcinomaLinks between mutant p53 and genomic instabilityThe more the messier: centrosome amplification as a novel biomarker for personalized treatment of colorectal cancersCentrosomal P4.1-associated protein is a new member of transcriptional coactivators for nuclear factor-kappaBCentrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM.Induction of centrosome amplification in p53 siRNA-treated human fibroblast cells by radiation exposure.Overexpression of polo-like kinase 1 (PLK1) and chromosomal instability in bladder cancer.Centrosomal Nlp is an oncogenic protein that is gene-amplified in human tumors and causes spontaneous tumorigenesis in transgenic mice.Transcriptional control of BubR1 by p53 and suppression of centrosome amplification by BubR153BP1 cooperates with p53 and functions as a haploinsufficient tumor suppressor in miceCentrosome number is controlled by a centrosome-intrinsic block to reduplication.Abnormal centrosome amplification in cells through the targeting of Ran-binding protein-1 by the human T cell leukemia virus type-1 Tax oncoproteinKrüppel-like factor 4 prevents centrosome amplification following gamma-irradiation-induced DNA damageRequirement of clathrin heavy chain for p53-mediated transcription.Mouse embryonic fibroblasts null for the Krüppel-like factor 4 gene are genetically unstable.Serine 312 phosphorylation is dispensable for wild-type p53 functions in vivo.Cilium, centrosome and cell cycle regulation in polycystic kidney disease.Mcph1/Brit1 deficiency promotes genomic instability and tumor formation in a mouse modelLoss of cyclin-dependent kinase 2 (CDK2) inhibitory phosphorylation in a CDK2AF knock-in mouse causes misregulation of DNA replication and centrosome duplication.Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition.Functional relationship among PLK2, PLK4 and ROCK2 to induce centrosome amplification.Amplified centrosomes may underlie aggressive disease course in pancreatic ductal adenocarcinoma.Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell deathCyclic pifithrin-alpha sensitizes wild type p53 tumor cells to antimicrotubule agent-induced apoptosis.Inhibition of Cdk2 activity decreases Aurora-A kinase centrosomal localization and prevents centrosome amplification in breast cancer cells.Disparities in breast cancer outcomes between Caucasian and African American women: a model for describing the relationship of biological and nonbiological factors.Phosphorylation of p53 is regulated by TPX2-Aurora A in xenopus oocytes.Roles of BCCIP in chromosome stability and cytokinesis.Tubulin targets in the pathobiology and therapy of glioblastoma multiforme. II. gamma-Tubulin.Genomic instability and colon carcinogenesis: from the perspective of genes.Genomic alterations as mediators of miRNA dysregulation in ovarian cancer.The helix-loop-helix protein ID1 localizes to centrosomes and rapidly induces abnormal centrosome numbers.Single-stranded DNA induces ataxia telangiectasia mutant (ATM)/p53-dependent DNA damage and apoptotic signals.
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Loss of p53 and centrosome hyperamplification.
@ast
Loss of p53 and centrosome hyperamplification.
@en
Loss of p53 and centrosome hyperamplification.
@nl
type
label
Loss of p53 and centrosome hyperamplification.
@ast
Loss of p53 and centrosome hyperamplification.
@en
Loss of p53 and centrosome hyperamplification.
@nl
prefLabel
Loss of p53 and centrosome hyperamplification.
@ast
Loss of p53 and centrosome hyperamplification.
@en
Loss of p53 and centrosome hyperamplification.
@nl
P2860
P356
P1433
P1476
Loss of p53 and centrosome hyperamplification
@en
P2093
Kenji Fukasawa
P2860
P2888
P304
P356
10.1038/SJ.ONC.1205707
P407
P577
2002-09-01T00:00:00Z
P5875
P6179
1046883420