Impact of gene expression noise on organismal fitness and the efficacy of natural selection.
about
Functionalities of expressed messenger RNAs revealed from mutant phenotypesInterplay between gene expression noise and regulatory network architectureDeterminative developmental cell lineages are robust to cell deathsAdjusting phenotypes by noise controlDeterminants of the rate of protein sequence evolutionNoise in biologyA genome-wide analysis of promoter-mediated phenotypic noise in Escherichia coliA Philosophical Perspective on Evolutionary Systems BiologyMicrobial consortia at steady supplyThe genotype-phenotype map of yeast complex traits: basic parameters and the role of natural selection.Mistranslation can enhance fitness through purging of deleterious mutations.Constitutive versus responsive gene expression strategies for growth in changing environmentsNeutral and adaptive explanations for an association between caste-biased gene expression and rate of sequence evolution.Constraining the metabolic genotype-phenotype relationship using a phylogeny of in silico methodsNoise-mean relationship in mutated promotersMutation induced extinction in finite populations: lethal mutagenesis and lethal isolation.Teasing apart translational and transcriptional components of stochastic variations in eukaryotic gene expression.How does evolution tune biological noise?Evaluation of gene association methods for coexpression network construction and biological knowledge discovery.Phenotypic heterogeneity is a selected trait in natural yeast populations subject to environmental stress.A Bayesian model for pooling gene expression studies that incorporates co-regulation informationUnder-dominance constrains the evolution of negative autoregulation in diploids.Promoter sequence determines the relationship between expression level and noise.Single-cell phenomics reveals intra-species variation of phenotypic noise in yeast.Over-expression of Arabidopsis AtCHR23 chromatin remodeling ATPase results in increased variability of growth and gene expression.Stochastic developmental variation, an epigenetic source of phenotypic diversity with far-reaching biological consequences.Reconciling molecular regulatory mechanisms with noise patterns of bacterial metabolic promoters in induced and repressed states.Selection on noise constrains variation in a eukaryotic promoter.Soluble oligomerization provides a beneficial fitness effect on destabilizing mutations.Asymmetrical Damage Partitioning in Bacteria: A Model for the Evolution of Stochasticity, Determinism, and Genetic Assimilation.An Individual-Based Diploid Model Predicts Limited Conditions Under Which Stochastic Gene Expression Becomes AdvantageousPhenotypic heterogeneity promotes adaptive evolution.Rapid, broad-scale gene expression evolution in experimentally harvested fish populations.Genomic evidence for elevated mutation rates in highly expressed genesThe genomic landscape and evolutionary resolution of antagonistic pleiotropy in yeast.The Genomic Landscape of Position Effects on Protein Expression Level and Noise in Yeast.Contrasting Frequencies and Effects of cis- and trans-Regulatory Mutations Affecting Gene Expression.Adaptive Genetic Robustness of Escherichia coli Metabolic Fluxes.Uncovering the functional constraints underlying the genomic organization of the odorant-binding protein genes.Additive, epistatic, and environmental effects through the lens of expression variability QTL in a twin cohort
P2860
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P2860
Impact of gene expression noise on organismal fitness and the efficacy of natural selection.
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Impact of gene expression nois ...... efficacy of natural selection.
@ast
Impact of gene expression nois ...... efficacy of natural selection.
@en
Impact of gene expression nois ...... efficacy of natural selection.
@nl
type
label
Impact of gene expression nois ...... efficacy of natural selection.
@ast
Impact of gene expression nois ...... efficacy of natural selection.
@en
Impact of gene expression nois ...... efficacy of natural selection.
@nl
prefLabel
Impact of gene expression nois ...... efficacy of natural selection.
@ast
Impact of gene expression nois ...... efficacy of natural selection.
@en
Impact of gene expression nois ...... efficacy of natural selection.
@nl
P2860
P356
P1476
Impact of gene expression nois ...... efficacy of natural selection.
@en
P2093
Jianzhi Zhang
P2860
P304
P356
10.1073/PNAS.1100059108
P407
P577
2011-04-04T00:00:00Z