Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles.
about
Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases?Infectivity versus Seeding in Neurodegenerative Diseases Sharing a Prion-Like MechanismThe spectrum of disease in chronic traumatic encephalopathyPaired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomesHeparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seedsIs tau ready for admission to the prion club?Untangling tau imagingFocus on Extracellular Vesicles: Exosomes and Their Role in Protein Trafficking and Biomarker Potential in Alzheimer's and Parkinson's DiseaseFocus on Extracellular Vesicles: Physiological Role and Signalling Properties of Extracellular Membrane VesiclesInsights into Mechanisms of Chronic NeurodegenerationPathogenic protein seeding in Alzheimer disease and other neurodegenerative disordersTangles, Toxicity, and Tau Secretion in AD - New Approaches to a Vexing ProblemThe role of tau in neurodegenerative diseases and its potential as a therapeutic targetProteolytic clearance of extracellular α-synuclein as a new therapeutic approach against Parkinson diseasePrion-like properties of Tau protein: the importance of extracellular Tau as a therapeutic targetPassive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy modelsInduced tauopathy in a novel 3D-culture model mediates neurodegenerative processes: a real-time study on biochipsThe preclinical phase of the pathological process underlying sporadic Alzheimer's diseaseThe Glymphatic System: A Beginner's GuideAlzheimer's disease and prion proteinThe Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer's DiseaseDistinct α-synuclein strains differentially promote tau inclusions in neuronsThe release and trans-synaptic transmission of Tau via exosomesAmeliorative Effects of Antioxidants on the Hippocampal Accumulation of Pathologic Tau in a Rat Model of Blast-Induced Traumatic Brain InjuryAlzheimer disease: a tale of two prionsBiophysical insights into how surfaces, including lipid membranes, modulate protein aggregation related to neurodegeneration.The Dynamics and Turnover of Tau Aggregates in Cultured Cells: INSIGHTS INTO THERAPIES FOR TAUOPATHIES.Biomarkers in the Diagnosis and Prognosis of Alzheimer's Disease.The relationship between iron dyshomeostasis and amyloidogenesis in Alzheimer's disease: Two sides of the same coin.Propagation of tau pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies.A high-throughput screening assay for determining cellular levels of total tau protein.Glial contributions to neurodegeneration in tauopathies.Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.Biology and genetics of prions causing neurodegenerationAcetylation: a new key to unlock tau's role in neurodegenerationSingle mutations in tau modulate the populations of fibril conformers through seed selection.Dual vulnerability of TDP-43 to calpain and caspase-3 proteolysis after neurotoxic conditions and traumatic brain injuryProteopathic tau seeding predicts tauopathy in vivo.Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer's disease.Human P301L-mutant tau expression in mouse entorhinal-hippocampal network causes tau aggregation and presynaptic pathology but no cognitive deficits
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P2860
Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Seeding of normal Tau by patho ...... sis of Alzheimer-like tangles.
@ast
Seeding of normal Tau by patho ...... sis of Alzheimer-like tangles.
@en
Seeding of normal Tau by patho ...... sis of Alzheimer-like tangles.
@nl
type
label
Seeding of normal Tau by patho ...... sis of Alzheimer-like tangles.
@ast
Seeding of normal Tau by patho ...... sis of Alzheimer-like tangles.
@en
Seeding of normal Tau by patho ...... sis of Alzheimer-like tangles.
@nl
prefLabel
Seeding of normal Tau by patho ...... sis of Alzheimer-like tangles.
@ast
Seeding of normal Tau by patho ...... sis of Alzheimer-like tangles.
@en
Seeding of normal Tau by patho ...... sis of Alzheimer-like tangles.
@nl
P2860
P356
P1476
Seeding of normal Tau by patho ...... sis of Alzheimer-like tangles.
@en
P2093
Jing L Guo
Virginia M-Y Lee
P2860
P304
15317-15331
P356
10.1074/JBC.M110.209296
P407
P577
2011-03-03T00:00:00Z