Wnt/β-catenin signaling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium. - Wikidata - thesis-toulmin - TriplyDB

Wnt/β-catenin signaling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium.

Wnt/β-catenin signaling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium.

http://www.wikidata.org/entity/Q34876177

about

Common stemness regulators of embryonic and cancer stem cells The relationship between COPD and lung cancer Wnt signaling pathway in non-small cell lung cancer LZTFL1 suppresses lung tumorigenesis by maintaining differentiation of lung epithelial cells.Multidimensional Roles of Collagen Triple Helix Repeat Containing 1 (CTHRC1) in Malignant Cancers Mechanism of Resistance and Novel Targets Mediating Resistance to EGFR and c-Met Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer Low-density lipoprotein receptor-related protein 6 (LRP6) rs10845498 polymorphism is associated with a decreased risk of non-small cell lung cancer Cell-state transitions regulated by SLUG are critical for tissue regeneration and tumor initiation Stem cells and cell therapies in lung biology and diseases: conference report.SOX2 gene regulates the transcriptional network of oncogenes and affects tumorigenesis of human lung cancer cells.β-catenin contributes to lung tumor development induced by EGFR mutations Regeneration of alveolar type I and II cells from Scgb1a1-expressing cells following severe pulmonary damage induced by bleomycin and influenza.Overexpression of collagen triple helix repeat containing 1 (CTHRC1) is associated with tumour aggressiveness and poor prognosis in human non-small cell lung cancer.FOXQ1, a novel target of the Wnt pathway and a new marker for activation of Wnt signaling in solid tumors.Evidence for tankyrases as antineoplastic targets in lung cancer.The river blindness drug Ivermectin and related macrocyclic lactones inhibit WNT-TCF pathway responses in human cancer.Rapid modelling of cooperating genetic events in cancer through somatic genome editing Loss of RhoA Exacerbates, Rather Than Dampens, Oncogenic K-Ras Induced Lung Adenoma Formation in Mice.A microRNA gene expression signature predicts response to erlotinib in epithelial cancer cell lines and targets EMT.Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness.A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy Tankyrase 1 polymorphism associated with an increased risk in developing non-small cell lung cancer in a Chinese population: a proof-of-principle study Foxm1 mediates cross talk between Kras/mitogen-activated protein kinase and canonical Wnt pathways during development of respiratory epithelium Role of WNT1-inducible-signaling pathway protein 1 in etoposide resistance in lung adenocarcinoma A549 cells Recapitulating tumour microenvironment in chitosan-gelatin three-dimensional scaffolds: an improved in vitro tumour model PIK3CA(H1047R) Accelerates and Enhances KRAS(G12D)-Driven Lung Tumorigenesis.RAS signaling and anti-RAS therapy: lessons learned from genetically engineered mouse models, human cancer cells, and patient-related studies.Wnt agonist attenuates liver injury and improves survival after hepatic ischemia/reperfusion.The role of Sox genes in lung morphogenesis and cancer.High expression of CTHRC1 promotes EMT of epithelial ovarian cancer (EOC) and is associated with poor prognosis.Nuclear LEF1/TCF4 correlate with poor prognosis but not with nuclear β-catenin in cerebral metastasis of lung adenocarcinomas Role of PI3K-AKT-mTOR and Wnt Signaling Pathways in Transition of G1-S Phase of Cell Cycle in Cancer Cells.β-catenin and Kras/Foxm1 signaling pathway are critical to restrict Sox9 in basal cells during pulmonary branching morphogenesis Non-small-cell lung cancer: molecular targeted therapy and personalized medicine - drug resistance, mechanisms, and strategies A preclinical evaluation of antimycin a as a potential antilung cancer stem cell agent.Control of alveolar differentiation by the lineage transcription factors GATA6 and HOPX inhibits lung adenocarcinoma metastasis KIF3A binds to β-arrestin for suppressing Wnt/β-catenin signalling independently of primary cilia in lung cancer.Balancing the developmental niches within the lung Skeletal metastasis: treatments, mouse models, and the Wnt signaling.Molecular determinants of lung development.

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Wnt/β-catenin signaling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium.

http://www.wikidata.org/entity/Q34876177

description

2011 nî lūn-bûn

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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2011 թվականի ապրիլին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Wnt/β-catenin signaling accele ...... phenotype on lung epithelium.

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Wnt/β-catenin signaling accele ...... phenotype on lung epithelium.

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Wnt/β-catenin signaling accele ...... phenotype on lung epithelium.

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type

label

Wnt/β-catenin signaling accele ...... phenotype on lung epithelium.

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Wnt/β-catenin signaling accele ...... phenotype on lung epithelium.

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Wnt/β-catenin signaling accele ...... phenotype on lung epithelium.

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prefLabel

Wnt/β-catenin signaling accele ...... phenotype on lung epithelium.

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Wnt/β-catenin signaling accele ...... phenotype on lung epithelium.

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Wnt/β-catenin signaling accele ...... phenotype on lung epithelium.

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Journal of Clinical Investigation

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Wnt/β-catenin signaling accele ...... r phenotype on lung epithelium

@en

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Amy C Durham

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Ashley M Goss

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Edward E Morrisey

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Eugenia C Pacheco-Pinedo

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Kathleen M Stewart

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Min Min Lu

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P2860

SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation

WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis.

A molecular mechanism for the effect of lithium on development

Somatic mutations affect key pathways in lung adenocarcinoma

Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy.

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5

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121

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21490395

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