Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.
about
The histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targetingEpigenetic regulation by histone demethylases in hypoxiaHigh-throughput screening to identify inhibitors of lysine demethylasesHistone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and preventionKDM5 interacts with Foxo to modulate cellular levels of oxidative stress8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase InhibitorsHistone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genesScreen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistanceThe histone demethylase dKDM5/LID interacts with the SIN3 histone deacetylase complex and shares functional similarities with SIN3.Distribution and prediction of catalytic domains in 2-oxoglutarate dependent dioxygenases.Folate deficiency facilitates recruitment of upstream binding factor to hot spots of DNA double-strand breaks of rRNA genes and promotes its transcriptionHistone demethylase RBP2 is critical for breast cancer progression and metastasis.H3K4 demethylase activities repress proliferative and postmitotic aging.Application of MassSQUIRM for quantitative measurements of lysine demethylase activity.Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate.Histone ubiquitination and deubiquitination in transcription, DNA damage response, and cancer.Proteotranscriptomic Profiling of 231-BR Breast Cancer Cells: Identification of Potential Biomarkers and Therapeutic Targets for Brain Metastasis.Epigenetic mechanisms in commonly occurring cancers.Mutations in the KDM5C ARID Domain and Their Plausible Association with Syndromic Claes-Jensen-Type Disease.Escape from Mitotic Arrest: An Unexpected Connection Between Microtubule Dynamics and Epigenetic Regulation of Centromeric Chromatin in Schizosaccharomyces pombe.Investigation of Histone Lysine-Specific Demethylase 5D KDM5D) Isoform Expression in Prostate Cancer Cell Lines: a System ApproachTranscriptional Regulation of JARID1B/KDM5B Histone Demethylase by Ikaros, Histone Deacetylase 1 (HDAC1), and Casein Kinase 2 (CK2) in B-cell Acute Lymphoblastic Leukemia.Depletion of histone demethylase KDM5B inhibits cell proliferation of hepatocellular carcinoma by regulation of cell cycle checkpoint proteins p15 and p27.Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen.Suppression of Enhancer Overactivation by a RACK7-Histone Demethylase ComplexEpigenetic regulation in adult stem cells and cancers.An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targetingPharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cellsKDM5 lysine demethylases are involved in maintenance of 3'UTR length.The methylation landscape of tumour metastasis.Histone H3K4 trimethylation: dynamic interplay with pre-mRNA splicing.Targeting epigenetic regulators for cancer therapy: modulation of bromodomain proteins, methyltransferases, demethylases, and microRNAs.Effect of histone deacetylase on prostate carcinoma.Pyrido[3,4-d]pyrimidin-4(3H)-one metabolism mediated by aldehyde oxidase is blocked by C2-substitutionRBP2 induces stem-like cancer cells by promoting EMT and is a prognostic marker for renal cell carcinoma.The Histone Demethylase KDM5 Activates Gene Expression by Recognizing Chromatin Context through Its PHD Reader Motif.siRNA targeting RBP2 inhibits expression, proliferation, tumorigenicity and invasion in thyroid carcinoma cellsHistone demethylase KDM5A regulates the ZMYND8-NuRD chromatin remodeler to promote DNA repair.
P2860
Q21092410-5B8C9FA0-A18F-40E8-BDF9-F006D9DB8518Q26768602-9EE2B8C0-B73A-4A15-84CB-582785820955Q26825704-C2397B02-4CC1-4B6F-90DE-C6ED6A389474Q26851462-087EB534-EB52-438E-9BEC-B439AA83BA83Q26994739-D9073354-7AEC-4F6A-805C-EE4B44CDE44BQ27312723-C046EBEB-AE12-4B98-85D7-51F6BF087CD5Q27644640-CC1F2486-3F8E-465A-87AD-69851E3E7D33Q28511595-9E761575-D04D-42F4-85B8-D15637ECA71DQ28818255-A4EE4D12-D25E-4080-B891-067257BC69C1Q30391612-B44EAE95-87DF-4A02-BD79-0A1ECE20F91EQ30525690-FBF736DA-C2BC-4E09-BBC3-21558EB262B3Q33558438-23B5C7B5-B116-4F21-96B7-26E363B21C41Q33582497-0EB872E8-3A16-476C-B1A4-52B6E0D32615Q33607821-8534131C-D755-4A93-B6DB-E055A3DD2F3AQ34204076-3DF9F728-79CA-4CD6-8F44-892379FE261AQ35170918-DDDCC8E3-C1BB-4B5B-9FDB-F08E12AC77ECQ35801707-5FDA2FCF-A575-482D-A3C6-78808F77D59BQ35971184-10D67725-A299-4B90-B648-8807C30E3FEAQ36040355-CAE71AA4-91AA-495D-9C59-B72FC5D8AFC4Q36286662-92DF434A-5099-4002-A57F-49B5EDD2CFD1Q36324695-C4C2DD9D-E1C7-4F69-91DE-233C8DEA0AFCQ36365254-25419B8B-044F-4A21-94E3-11503C4C0586Q36502209-FD6D1A27-87D8-4C73-AB5A-0EB5109B9A38Q36594686-68E6B9B9-9C26-40A7-91CE-A81AAAE2A54BQ36616276-36179314-9E23-4680-B84F-17B4313759F3Q36725098-52289F33-393B-4B0D-9B93-69228625D45EQ36783309-88A1726F-B4AD-4DB8-918A-E382C453826CQ37366481-2BCF2BFC-16B3-483A-B828-91CBE0FD4654Q37401076-4B35D8DE-E3AE-4FFC-BDC1-7724624649F9Q37548974-6929A890-20CD-4093-917F-FA7A9BA1185AQ37603840-AD424724-1D64-4E7D-9C8D-A83DAFF52284Q38063931-0C11DB43-EB6D-4D8D-8543-E0C3BA7BE59CQ38583533-653BEA0C-73A0-4463-9780-E0D242369914Q38707876-B590DF3F-03C9-42A3-AD01-63EBC9D1AE55Q38798403-E13708AE-BCC8-452E-B3E2-36B3AF500419Q39400725-61FA96A9-8928-4EF1-B54F-0AFE5A7C7713Q39696157-815AF88A-112B-47D8-93E6-44B3554A9392Q40206242-E301CD42-2924-4CDB-BEE9-EF1B13B1C3C5Q41976557-97C01EF9-BCA0-457B-943F-496150776982Q47826961-37D55371-3752-4EDD-9F87-7BF0689F3905
P2860
Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.
@ast
Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.
@en
Epigenetic Regulation by Lysine Demethylase 5
@nl
type
label
Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.
@ast
Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.
@en
Epigenetic Regulation by Lysine Demethylase 5
@nl
prefLabel
Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.
@ast
Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer.
@en
Epigenetic Regulation by Lysine Demethylase 5
@nl
P2093
P2860
P356
P1433
P1476
Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer
@en
P2093
Joyce Sayegh
Lauren P Blair
Mike Ran Zou
P2860
P304
P356
10.3390/CANCERS3011383
P50
P577
2011-03-01T00:00:00Z