Transient receptor potential channels: targeting pain at the source.
about
Synthesis of lipid mediators during UVB-induced inflammatory hyperalgesia in rats and micePrimary afferent activation of thermosensitive TRPV1 triggers asynchronous glutamate release at central neuronsRedox and trace metal regulation of ion channels in the pain pathwayBiological Roles of Resolvins and Related Substances in the Resolution of PainDeciphering Subtype-Selective Modulations in TRPA1 Biosensor ChannelsThe perception and endogenous modulation of painModulation of the endocannabinoid system: vulnerability factor and new treatment target for stimulant addictionThe functional and anatomical dissection of somatosensory subpopulations using mouse geneticsTRPV1 in brain is involved in acetaminophen-induced antinociceptionUpregulation of the transient receptor potential ankyrin 1 ion channel in the inflamed human and mouse colon and its protective rolesA Tarantula-Venom Peptide Antagonizes the TRPA1 Nociceptor Ion Channel by Binding to the S1–S4 Gating DomainNociceptive TRP Channels: Sensory Detectors and Transducers in Multiple Pain PathologiesDifferential Activation of TRP Channels in the Adult Rat Spinal Substantia Gelatinosa by Stereoisomers of Plant-Derived ChemicalsEmerging targets in neuroinflammation-driven chronic painTransient receptor potential channels as therapeutic targetsSpinal 12-lipoxygenase-derived hepoxilin A3 contributes to inflammatory hyperalgesia via activation of TRPV1 and TRPA1 receptorsA re-evaluation of 9-HODE activity at TRPV1 channels in comparison with anandamide: enantioselectivity and effects at other TRP channels and in sensory neuronsArtepillin C, a major ingredient of Brazilian propolis, induces a pungent taste by activating TRPA1 channelsThe pore-domain of TRPA1 mediates the inhibitory effect of the antagonist 6-methyl-5-(2-(trifluoromethyl)phenyl)-1H-indazoleThy1.2 YFP-16 transgenic mouse labels a subset of large-diameter sensory neurons that lack TRPV1 expressionTRPA1 is a component of the nociceptive response to CO2Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammationPotency of irritation by benzylidenemalononitriles in humans correlates with TRPA1 ion channel activationTransient receptor potential channel polymorphisms are associated with the somatosensory function in neuropathic pain patientsFacilitation of TRPV4 by TRPV1 is required for itch transmission in some sensory neuron populationsSpatial temperature gradients guide axonal outgrowthTRPV1 ligands with hyperthermic, hypothermic and no temperature effects in ratsConsequences of a human TRPA1 genetic variant on the perception of nociceptive and olfactory stimuliClinical pharmacology of analgesics assessed with human experimental pain models: bridging basic and clinical research.The amnesiac gene is involved in the regulation of thermal nociception in Drosophila melanogaster.Retinoids activate the irritant receptor TRPV1 and produce sensory hypersensitivityComputed ABC Analysis for Rational Selection of Most Informative Variables in Multivariate DataTRPV1 and TRPA1 mediate peripheral nitric oxide-induced nociception in mice.Small molecule activators of TRPML3Transient receptor potential (TRP) channels: a clinical perspectiveIdentifying the Ion Channels Responsible for Signaling Gastro-Intestinal Based PainTRPV1 channels are critical brain inflammation detectors and neuropathic pain biomarkers in mice.In vivo pharmacology of endocannabinoids and their metabolic inhibitors: therapeutic implications in Parkinson's disease and abuse liabilityMolecular Surgery Concept from Bench to Bedside: A Focus on TRPV1+ Pain-Sensing Neurons.Transient Receptor Potential Vanilloid 1 is essential for cisplatin-induced heat hyperalgesia in mice
P2860
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P2860
Transient receptor potential channels: targeting pain at the source.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Transient receptor potential channels: targeting pain at the source.
@ast
Transient receptor potential channels: targeting pain at the source.
@en
Transient receptor potential channels: targeting pain at the source.
@nl
type
label
Transient receptor potential channels: targeting pain at the source.
@ast
Transient receptor potential channels: targeting pain at the source.
@en
Transient receptor potential channels: targeting pain at the source.
@nl
prefLabel
Transient receptor potential channels: targeting pain at the source.
@ast
Transient receptor potential channels: targeting pain at the source.
@en
Transient receptor potential channels: targeting pain at the source.
@nl
P2093
P2860
P356
P1476
Transient receptor potential channels: targeting pain at the source.
@en
P2093
Ardem Patapoutian
Clifford J Woolf
Simon Tate
P2860
P2888
P356
10.1038/NRD2757
P577
2009-01-01T00:00:00Z