MeCP2 is required for global heterochromatic and nucleolar changes during activity-dependent neuronal maturation. - Wikidata - thesis-toulmin - TriplyDB

MeCP2 is required for global heterochromatic and nucleolar changes during activity-dependent neuronal maturation.

MeCP2 is required for global heterochromatic and nucleolar changes during activity-dependent neuronal maturation.

http://www.wikidata.org/entity/Q34988096

about

MeCP2 and the enigmatic organization of brain chromatin. Implications for depression and cocaine addiction DNA modifications: function and applications in normal and disease States Emerging roles of the neuronal nucleolus Nuclear organization and 3D chromatin architecture in cognition and neuropsychiatric disorders A role for MeCP2 in switching gene activity via chromatin unfolding and HP1γ displacement.The Crucial Role of DNA Methylation and MeCP2 in Neuronal Function DNA methylation reader MECP2: cell type- and differentiation stage-specific protein distribution.MeCP2 dependent heterochromatin reorganization during neural differentiation of a novel Mecp2-deficient embryonic stem cell reporter line.Overlapping and non-overlapping functions of condensins I and II in neural stem cell divisions.Neuronal nucleus and cytoplasm volume deficit in children with autism and volume increase in adolescents and adults.Genotype-specific effects of Mecp2 loss-of-function on morphology of Layer V pyramidal neurons in heterozygous female Rett syndrome model mice.PHF6 Degrees of Separation: The Multifaceted Roles of a Chromatin Adaptor Protein.Effects of Mecp2 loss of function in embryonic cortical neurons: a bioinformatics strategy to sort out non-neuronal cells variability from transcriptome profiling.Phosphorylation of distinct sites in MeCP2 modifies cofactor associations and the dynamics of transcriptional regulation MeCP2 as a genome-wide modulator: the renewal of an old story.Requirement of Neuronal Ribosome Synthesis for Growth and Maintenance of the Dendritic Tree Epigenetic mechanisms in neurological disease Impaired in vivo binding of MeCP2 to chromatin in the absence of its DNA methyl-binding domain From Function to Phenotype: Impaired DNA Binding and Clustering Correlates with Clinical Severity in Males with Missense Mutations in MECP2.Chromatin context and ncRNA highlight targets of MeCP2 in brain.Something silent this way forms: the functional organization of the repressive nuclear compartment.Rett syndrome and MeCP2.Methyl-CpG-binding domain proteins: readers of the epigenome.MECP2, a multi-talented modulator of chromatin architecture.Xq28 (MECP2) microdeletions are common in mutation-negative females with Rett syndrome and cause mild subtypes of the disease Disease modeling using embryonic stem cells: MeCP2 regulates nuclear size and RNA synthesis in neurons.GLP inhibits heterochromatin clustering and myogenic differentiation by repressing MeCP2.Loss of neuronal 3D chromatin organization causes transcriptional and behavioural deficits related to serotonergic dysfunction.Nuclear Architecture in the Nervous System: Development, Function, and Neurodevelopmental Diseases

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P2860

MeCP2 is required for global heterochromatic and nucleolar changes during activity-dependent neuronal maturation.

http://www.wikidata.org/entity/Q34988096

description

2011 nî lūn-bûn

@nan

2011 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

MeCP2 is required for global h ...... dependent neuronal maturation.

@ast

MeCP2 is required for global h ...... dependent neuronal maturation.

@en

MeCP2 is required for global h ...... dependent neuronal maturation.

@nl

type

label

MeCP2 is required for global h ...... dependent neuronal maturation.

@ast

MeCP2 is required for global h ...... dependent neuronal maturation.

@en

MeCP2 is required for global h ...... dependent neuronal maturation.

@nl

prefLabel

MeCP2 is required for global h ...... dependent neuronal maturation.

@ast

MeCP2 is required for global h ...... dependent neuronal maturation.

@en

MeCP2 is required for global h ...... dependent neuronal maturation.

@nl

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P356

J.NBD.2011.03.011

P1433

Neurobiology of Disease

P1476

MeCP2 is required for global h ...... -dependent neuronal maturation

@en

P2093

Dag H Yasui

http://www.w3.org/2001/XMLSchema#string

Diane I Schroeder

http://www.w3.org/2001/XMLSchema#string

Karen N Leung

http://www.w3.org/2001/XMLSchema#string

Keith Dunaway

http://www.w3.org/2001/XMLSchema#string

Malaika K Singleton

http://www.w3.org/2001/XMLSchema#string

Michael L Gonzales

http://www.w3.org/2001/XMLSchema#string

P2860

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2

Rett syndrome and MeCP2: linking epigenetics and neuronal function

Inhibitors of differentiation (ID1, ID2, ID3 and ID4) genes are neuronal targets of MeCP2 that are elevated in Rett syndrome

Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription

Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation

The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats

Analysis of protein domains and Rett syndrome mutations indicate that multiple regions influence chromatin-binding dynamics of the chromatin-associated protein MECP2 in vivo

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190-200

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scholarly article

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10.1016/J.NBD.2011.03.011

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1

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43

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Janine M. LaSalle

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2011-03-21T00:00:00Z

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50594127

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21420494

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3096744

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