Brd4 is displaced from HPV replication factories as they expand and amplify viral DNA
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The Role of the DNA Damage Response throughout the Papillomavirus Life CycleAn Epigenetic Compound Library Screen Identifies BET Inhibitors That Promote HSV-1 and -2 Replication by Bridging P-TEFb to Viral Gene Promoters through BRD4The human papillomavirus type 16 L1 protein directly interacts with E2 and enhances E2-dependent replication and transcription activation.Papillomavirus genomes associate with BRD4 to replicate at fragile sites in the host genome.Productive replication of human papillomavirus 31 requires DNA repair factor Nbs1.Human Papillomavirus Type 18 cis-Elements Crucial for Segregation and Latency.A proteomic approach to discover and compare interacting partners of papillomavirus E2 proteins from diverse phylogenetic groupsImpact of the DNA Damage Response on Human Papillomavirus Chromatin.DNA Damage Reduces the Quality, but Not the Quantity of Human Papillomavirus 16 E1 and E2 DNA ReplicationTandemly Integrated HPV16 Can Form a Brd4-Dependent Super-Enhancer-Like Element That Drives Transcription of Viral OncogenesBrd4 Activates Early Viral Transcription upon Human Papillomavirus 18 Infection of Primary Keratinocytes.Sp100 provides intrinsic immunity against human papillomavirus infection.Involvement of Brd4 in different steps of the papillomavirus life cycle.Therapeutics Targeting Protein Acetylation Perturb Latency of Human Viruses.Association of Human Papillomavirus 16 E2 with Rad50-Interacting Protein 1 Enhances Viral DNA Replication.DAXX modulates human papillomavirus early gene expression and genome replication in U2OS cells.Levels of the E2 interacting protein TopBP1 modulate papillomavirus maintenance stage replication.Modulation of the DNA damage response during the life cycle of human papillomaviruses.Evidence supporting a role for TopBP1 and Brd4 in the initiation but not continuation of human papillomavirus 16 E1/E2-mediated DNA replication.Homologous Recombination Repair Factors Rad51 and BRCA1 Are Necessary for Productive Replication of Human Papillomavirus 31.Targeting Persistent Human Papillomavirus Infection.Integration of Human Papillomavirus Genomes in Head and Neck Cancer: Is It Time to Consider a Paradigm Shift?The Deacetylase SIRT1 Regulates the Replication Properties of Human Papillomavirus 16 E1 and E2.HPV31 utilizes the ATR-Chk1 pathway to maintain elevated RRM2 levels and a replication-competent environment in differentiating Keratinocytes.Mechanisms by which HPV Induces a Replication Competent Environment in Differentiating Keratinocytes.Sp100 colocalizes with HPV replication foci and restricts the productive stage of the infectious cycleHPV Replication Regulation by Acetylation of a Conserved Lysine in the E2 Protein.HPV integration hijacks and multimerizes a cellular enhancer to generate a viral-cellular super-enhancer that drives high viral oncogene expression.Plasmid Partitioning by Human Tumor Viruses.
P2860
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P2860
Brd4 is displaced from HPV replication factories as they expand and amplify viral DNA
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2013 nî lūn-bûn
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2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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Brd4 is displaced from HPV replication factories as they expand and amplify viral DNA
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Brd4 is displaced from HPV replication factories as they expand and amplify viral DNA
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Brd4 is displaced from HPV replication factories as they expand and amplify viral DNA
@ast
Brd4 is displaced from HPV replication factories as they expand and amplify viral DNA
@en
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Brd4 is displaced from HPV replication factories as they expand and amplify viral DNA
@ast
Brd4 is displaced from HPV replication factories as they expand and amplify viral DNA
@en
P2093
P2860
P1433
P1476
Brd4 is displaced from HPV replication factories as they expand and amplify viral DNA
@en
P2093
Cheng-Ming Chiang
Dong Wook Kang
Moon Kyoo Jang
Nozomi Sakakibara
Shwu-Yuan Wu
P2860
P304
P356
10.1371/JOURNAL.PPAT.1003777
P577
2013-11-21T00:00:00Z