Intracellular leptin-signaling pathways in hypothalamic neurons: the emerging role of phosphatidylinositol-3 kinase-phosphodiesterase-3B-cAMP pathway
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HPRT-deficiency dysregulates cAMP-PKA signaling and phosphodiesterase 10A expression: mechanistic insight and potential target for Lesch-Nyhan Disease?Postnatal growth after intrauterine growth restriction alters central leptin signal and energy homeostasis.Hypothalamic KLF4 mediates leptin's effects on food intake via AgRPInvolvement of hypothalamic PI3K-STAT3 signalling in regulating appetite suppression mediated by amphetamine.Leptin signaling.Cyclic AMP sensor EPAC proteins and energy homeostasis.Chronic sleep fragmentation during the sleep period induces hypothalamic endoplasmic reticulum stress and PTP1b-mediated leptin resistance in male mice.Leptin at gender-specific concentrations does not affect glucose transport, expression of glucose transporters and leptin receptors in human lymphocytes.Phosphodiesterase-3B is expressed in proopiomelanocortin and neuropeptide Y neurons in the mouse hypothalamus.From PDE3B to the regulation of energy homeostasisLeptin receptor expressing neurons express phosphodiesterase-3B (PDE3B) and leptin induces STAT3 activation in PDE3B neurons in the mouse hypothalamus.Phosphatidylinositol 3-kinase is an upstream regulator of the phosphodiesterase 3B pathway of leptin signalling that may not involve activation of Akt in the rat hypothalamus.Effects of leptin on pedunculopontine nucleus (PPN) neurons.Leptin, resistin and visfatin: the missing link between endocrine metabolic disorders and immunity.Antenatal glucocorticoid exposure enhances the inhibition of adrenal steroidogenesis by leptin in a sex-specific fashion.A novel thermoregulatory role for PDE10A in mouse and human adipocytesRole of G-proteins in the effects of leptin on pedunculopontine nucleus neurons.Clock genes and clock-controlled genes in the regulation of metabolic rhythms.Non-alcoholic fatty liver disease: the role of nuclear receptors and circadian rhythmicity.Transcriptomic analysis and plasma metabolomics in Aldh16a1-null mice reveals a potential role of ALDH16A1 in renal function.Evidence suggesting phosphodiesterase-3B regulation of NPY/AgRP gene expression in mHypoE-46 hypothalamic neurons.Eat and Death: Chronic Over-Eating.Effects of Fat and Sugar, Either Consumed or Infused toward the Brain, on Hypothalamic ER Stress Markers.Phosphodiesterase-3B-cAMP pathway of leptin signalling in the hypothalamus is impaired during the development of diet-induced obesity in FVB/N mice.Combined inhibition of PI3Kβ and PI3Kγ reduces fat mass by enhancing α-MSH-dependent sympathetic drive.Hypothalamic Phosphodiesterase 3B Pathway Mediates Anorectic and Body Weight-Reducing Effects of Insulin in Male Mice.Early life stress experience may blunt hypothalamic leptin signalling.Central dopamine action modulates neuropeptide-controlled appetite via the hypothalamic PI3K/NF-κB-dependent mechanism.Leptin influences the excitability of area postrema neurons.Diet-Induced Obesity and the Mechanism of Leptin Resistance.
P2860
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P2860
Intracellular leptin-signaling pathways in hypothalamic neurons: the emerging role of phosphatidylinositol-3 kinase-phosphodiesterase-3B-cAMP pathway
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Intracellular leptin-signaling ...... sphodiesterase-3B-cAMP pathway
@ast
Intracellular leptin-signaling ...... sphodiesterase-3B-cAMP pathway
@en
type
label
Intracellular leptin-signaling ...... sphodiesterase-3B-cAMP pathway
@ast
Intracellular leptin-signaling ...... sphodiesterase-3B-cAMP pathway
@en
prefLabel
Intracellular leptin-signaling ...... sphodiesterase-3B-cAMP pathway
@ast
Intracellular leptin-signaling ...... sphodiesterase-3B-cAMP pathway
@en
P2860
P356
P1433
P1476
Intracellular leptin-signaling ...... sphodiesterase-3B-cAMP pathway
@en
P2093
Abhiram Sahu
P2860
P304
P356
10.1159/000326785
P577
2011-04-05T00:00:00Z