Severity of lung injury in cyclooxygenase-2-deficient mice is dependent on reduced prostaglandin E(2) production.
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Feedback amplification of fibrosis through matrix stiffening and COX-2 suppressionResolution of Inflammation: What Controls Its Onset?Role of matrix metalloproteinases in the pathogenesis of idiopathic pulmonary fibrosisGenetically manipulated mouse models of lung disease: potential and pitfallsMulti-walled carbon nanotubes induce COX-2 and iNOS expression via MAP kinase-dependent and -independent mechanisms in mouse RAW264.7 macrophagesIdentification of drug-specific pathways based on gene expression data: application to drug induced lung injury.Tgf-Beta isoform specific regulation of airway inflammation and remodelling in a murine model of asthma.Prostaglandin E(2) induces fibroblast apoptosis by modulating multiple survival pathways.Interaction of apoptotic cells with macrophages upregulates COX-2/PGE2 and HGF expression via a positive feedback loop.Matrix metalloproteinase-19 is a key regulator of lung fibrosis in mice and humansSirt1 activation protects the mouse renal medulla from oxidative injury.PGE(2) inhibition of TGF-beta1-induced myofibroblast differentiation is Smad-independent but involves cell shape and adhesion-dependent signaling.A prostacyclin analogue, iloprost, protects from bleomycin-induced pulmonary fibrosis in miceFollowing the path of CCL2 from prostaglandins to periostin in lung fibrosisDiminished prostaglandin E2 contributes to the apoptosis paradox in idiopathic pulmonary fibrosisLung myofibroblasts are characterized by down-regulated cyclooxygenase-2 and its main metabolite, prostaglandin E2.Involvement of cyclooxygenase-2 and prostaglandins in the molecular pathogenesis of inflammatory lung diseases.A novel genomic signature with translational significance for human idiopathic pulmonary fibrosis.Wood smoke enhances cigarette smoke-induced inflammation by inducing the aryl hydrocarbon receptor repressor in airway epithelial cells15-epi-lipoxin A4 reduces the mortality of prematurely born pups in a mouse model of infection-induced preterm birth.Airway remodeling in murine asthma correlates with a defect in PGE2 synthesis by lung fibroblasts.Prostaglandin E₂ protects murine lungs from bleomycin-induced pulmonary fibrosis and lung dysfunction.Eicosanoids and respiratory viral infection: coordinators of inflammation and potential therapeutic targets.Cyclooxygenase-2 deficiency exacerbates bleomycin-induced lung dysfunction but not fibrosisSARS-CoV regulates immune function-related gene expression in human monocytic cells.Parecoxib reduced ventilation induced lung injury in acute respiratory distress syndromeVariable prostaglandin E2 resistance in fibroblasts from patients with usual interstitial pneumonia.Lipopolysaccharide-induced cyclooxygenase-2 expression in mouse transformed Clara cellsThe role of cyclooxygenase-2 in mechanical ventilation-induced lung injury.Contribution of alveolar type II cell-derived cyclooxygenase-2 to basal airway function, lung inflammation, and lung fibrosis.Epigenetic regulation of cyclooxygenase-2 by methylation of c8orf4 in pulmonary fibrosisHepatocyte growth factor regulates cyclooxygenase-2 expression via beta-catenin, Akt, and p42/p44 MAPK in human bronchial epithelial cells.Lung fibroblast repair functions in patients with chronic obstructive pulmonary disease are altered by multiple mechanisms.Regulation of myofibroblast differentiation by cardiac glycosidesEicosanoid lipid mediators in fibrotic lung diseases: ready for prime time?Suppression of von Hippel-Lindau Protein in Fibroblasts Protects against Bleomycin-Induced Pulmonary Fibrosis.Differential responses in the lungs of newborn mouse pups exposed to 85% or >95% oxygenEvaluation of the Effects of Caffeic Acid Phenethyl Ester on Prostaglandin E2 and Two Key Cytokines Involved in Bleomycin-induced Pulmonary FibrosisCOX-2 from the injury milieu is critical for the initiation of periosteal progenitor cell mediated bone healingProstaglandin E2 mediates IL-1beta-related fibroblast mitogenic effects in acute lung injury through differential utilization of prostanoid receptors.
P2860
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P2860
Severity of lung injury in cyclooxygenase-2-deficient mice is dependent on reduced prostaglandin E(2) production.
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Severity of lung injury in cyc ...... prostaglandin E(2) production.
@ast
Severity of lung injury in cyc ...... prostaglandin E(2) production.
@en
type
label
Severity of lung injury in cyc ...... prostaglandin E(2) production.
@ast
Severity of lung injury in cyc ...... prostaglandin E(2) production.
@en
prefLabel
Severity of lung injury in cyc ...... prostaglandin E(2) production.
@ast
Severity of lung injury in cyc ...... prostaglandin E(2) production.
@en
P2093
P2860
P1476
Severity of lung injury in cyc ...... prostaglandin E(2) production
@en
P2093
Carmel B Nanthakumar
Caroline P D Wheeler-Jones
Danielle M Copeman
Geoffrey J Bellingan
Geoffrey J Laurent
Martyn L Foster
Rebecca J Hodges
Stephen E Bottoms
Stephen L Hart
P2860
P304
P356
10.1016/S0002-9440(10)63423-2
P407
P577
2004-11-01T00:00:00Z