The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation
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Advances in Autophagy Regulatory MechanismsAutophagy signal transduction by ATG proteins: from hierarchies to networksStructure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes.Regulation of autophagy by Beclin 1 in the heartmTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1Mutation-Structure-Function Relationship Based Integrated Strategy Reveals the Potential Impact of Deleterious Missense Mutations in Autophagy Related Proteins on Hepatocellular Carcinoma (HCC): A Comprehensive Informatics ApproachDual roles of extracellular signal-regulated kinase (ERK) in quinoline compound BPIQ-induced apoptosis and anti-migration of human non-small cell lung cancer cellsRegulation of Beclin 1 Protein Phosphorylation and Autophagy by Protein Phosphatase 2A (PP2A) and Death-associated Protein Kinase 3 (DAPK3).Beclin orthologs: integrative hubs of cell signaling, membrane trafficking, and physiologyCoordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer.Conformational Flexibility Enables the Function of a BECN1 Region Essential for Starvation-Mediated AutophagyMicrofilariae of Brugia malayi Inhibit the mTOR Pathway and Induce Autophagy in Human Dendritic CellsFocal Adhesion Kinase-mediated Phosphorylation of Beclin1 Protein Suppresses Cardiomyocyte Autophagy and Initiates Hypertrophic Growth.Integrative metabolomics as emerging tool to study autophagy regulation.The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14.Molecular Functions of Glycoconjugates in Autophagy.Fine-tuning autophagy: from transcriptional to posttranslational regulation.Conformational flexibility of BECN1: Essential to its key role in autophagy and beyond.Autophagy in leukocytes and other cells: mechanisms, subsystem organization, selectivity, and links to innate immunity.Mechanisms of Autophagy Initiation.Targeting neuronal MAPK14/p38α activity to modulate autophagy in the Alzheimer disease brain.The BECN1 N-terminal domain is intrinsically disordered.TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation.Identifying intrinsically disordered protein regions likely to undergo binding-induced helical transitionsTRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis.CaMKII-mediated Beclin 1 phosphorylation regulates autophagy that promotes degradation of Id and neuroblastoma cell differentiationDistribution of H3K27me3, H3K9me3, and H3K4me3 along autophagy-related genes highly expressed in starved zebrafish myotubes.The problem of pyridinyl imidazole class inhibitors of MAPK14/p38α and MAPK11/p38β in autophagy research.A Quinone-Containing Compound Enhances Camptothecin-Induced Apoptosis of Lung Cancer Through Modulating Endogenous ROS and ERK Signaling.Vps34 Kinase Domain Dynamics Regulate the Autophagic PI 3-Kinase Complex.ULK1 phosphorylates Ser30 of BECN1 in association with ATG14 to stimulate autophagy induction.A Molecular Perspective of Mammalian Autophagosome Biogenesis.Salinomycin, as an autophagy modulator-- a new avenue to anticancer: a review.TAK1 mediates excessive autophagy via p38 and ERK in cisplatin-induced acute kidney injury.Increased autophagy blocks HER2-mediated breast tumorigenesis.Beclin 1 Phosphorylation - at the Center of Autophagy RegulationDifferences in the starvation-induced autophagy response in MDA-MB-231 and MCF-7 breast cancer cellsAssociation Analysis of Somatic Copy Number Alteration Burden With Breast Cancer Survival
P2860
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P2860
The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation
description
2015 nî lūn-bûn
@nan
2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
The stress-responsive kinases ...... rough Beclin 1 phosphorylation
@ast
The stress-responsive kinases ...... rough Beclin 1 phosphorylation
@en
type
label
The stress-responsive kinases ...... rough Beclin 1 phosphorylation
@ast
The stress-responsive kinases ...... rough Beclin 1 phosphorylation
@en
prefLabel
The stress-responsive kinases ...... rough Beclin 1 phosphorylation
@ast
The stress-responsive kinases ...... rough Beclin 1 phosphorylation
@en
P2093
P2860
P356
P1433
P1476
The stress-responsive kinases ...... rough Beclin 1 phosphorylation
@en
P2093
Beth Levine
Rhea Sumpter
Sangita Sinha
Yongjie Wei
Zhongju Zou
P2860
P356
10.7554/ELIFE.05289
P407
P577
2015-02-18T00:00:00Z