Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes. - Wikidata - thesis-toulmin - TriplyDB

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.

http://www.wikidata.org/entity/Q35234637

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Expression of evolutionarily novel genes in tumors Restricting retrotransposons: a review Guardian of the Human Genome: Host Defense Mechanisms against LINE-1 Retrotransposition Post-Transcriptional Control of LINE-1 Retrotransposition by Cellular Host Factors in Somatic Cells Roles for retrotransposon insertions in human disease Historical review of the causes of cancer Insertion of Retrotransposons at Chromosome Ends: Adaptive Response to Chromosome Maintenance Transposable element detection from whole genome sequence data ADAR1, inosine and the immune sensing system: distinguishing self from non-self Potential of epigenetic therapies in the management of solid tumors The Fine LINE: Methylation Drawing the Cancer Landscape The Influence of LINE-1 and SINE Retrotransposons on Mammalian Genomes Endogenous retroviral promoter exaptation in human cancer The aging clock and circadian control of metabolism and genome stability piRNA involvement in genome stability and human cancer Deciphering fact from artifact when using reporter assays to investigate the roles of host factors on L1 retrotransposition Activation of individual L1 retrotransposon instances is restricted to cell-type dependent permissive loci LINE-1 activity as molecular basis for genomic instability associated with light exposure at night piRNAs derived from ancient viral processed pseudogenes as transgenerational sequence-specific immune memory in mammals The Role of Somatic L1 Retrotransposition in Human Cancers.A comprehensive approach to expression of L1 loci.Dynamic silencing of somatic L1 retrotransposon insertions reflects the developmental and cellular contexts of their genomic integration.Reading LINEs within the cocaine addicted brain.digit-a tool for detection and identification of genomic interchromosomal translocations Selective elimination of long INterspersed element-1 expressing tumour cells by targeted expression of the HSV-TK suicide gene.Sequencing, identification and mapping of primed L1 elements (SIMPLE) reveals significant variation in full length L1 elements between individuals Phosphorylation of ORF1p is required for L1 retrotransposition.Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells.Mobile element insertions are frequent in oesophageal adenocarcinomas and can mislead paired-end sequencing analysis.Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin.Long Interspersed Element Sequencing (L1-Seq): A Method to Identify Somatic LINE-1 Insertions in the Human Genome.Modeling the integration of bacterial rRNA fragments into the human cancer genome Next-generation sequencing-based detection of germline L1-mediated transductions.Genome-wide characterization of human L1 antisense promoter-driven transcripts LINE-1 expression and retrotransposition in Barrett's esophagus and esophageal carcinoma Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolution.The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts Population and clinical genetics of human transposable elements in the (post) genomic era.Discovery and characterization of Alu repeat sequences via precise local read assembly.Somatizing the transposons action.

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Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.

http://www.wikidata.org/entity/Q35234637

description

2014 nî lūn-bûn

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2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Mobile DNA in cancer. Extensiv ...... ansposition in cancer genomes.

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Mobile DNA in cancer. Extensiv ...... ansposition in cancer genomes.

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Mobile DNA in cancer. Extensiv ...... ansposition in cancer genomes.

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Mobile DNA in cancer. Extensiv ...... ansposition in cancer genomes.

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Mobile DNA in cancer. Extensiv ...... ansposition in cancer genomes.

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SCIENCE.1251343

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Mobile DNA in cancer. Extensiv ...... ansposition in cancer genomes.

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Adam P Butler

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Adam Shlien

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Adrienne M Flanagan

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Andrea L Richardson

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Andy G Lynch

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Anne Y Warren

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Christodoulos P Pipinikas

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Christopher Foster

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Christos Sotiriou

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Claire Hardy

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P2860

Initial sequencing and analysis of the human genome

Retrotransposition of gene transcripts leads to structural variation in mammalian genomes

Hot L1s account for the bulk of retrotransposition in the human population

An integrated encyclopedia of DNA elements in the human genome

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

Mutational processes molding the genomes of 21 breast cancers

Comprehensive molecular characterization of human colon and rectal cancer

Paired-end mapping reveals extensive structural variation in the human genome

Identifying related L1 retrotransposons by analyzing 3' transduced sequences

L1 and HERV-W retrotransposons are hypomethylated in human ovarian carcinomas

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Anne-Lise Børresen-Dale

Serena Nik-Zainal

Christine Desmedt

Ultan McDermott

Ludmil B. Alexandrov

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