Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state.
about
Histone Modifications, Modifiers and Readers in Melanoma Resistance to Targeted and Immune TherapyAdapt, Recycle, and Move on: Proteostasis and Trafficking Mechanisms in MelanomaMicroenvironment-derived factors driving metastatic plasticity in melanoma.NFIB Mediates BRN2 Driven Melanoma Cell Migration and Invasion Through Regulation of EZH2 and MITF.Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cellsYAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of EnhancersIdentification of High-Impact cis-Regulatory Mutations Using Transcription Factor Specific Random Forest ModelsExpression of CD133 and CD44 in glioblastoma stem cells correlates with cell proliferation, phenotype stability and intra-tumor heterogeneity.MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment.Interleukin-like EMT inducer regulates partial phenotype switching in MITF-low melanoma cell linesTead and AP1 Coordinate Transcription and Motility.Nuclear localization of TEF3-1 promotes cell cycle progression and angiogenesis in cancer.BRAF(V600E) Kinase Domain Duplication Identified in Therapy-Refractory Melanoma Patient-Derived XenograftsZEB1-mediated melanoma cell plasticity enhances resistance to MAPK inhibitors.Cooperative binding of AP-1 and TEAD4 modulates the balance between vascular smooth muscle and hemogenic cell fateTranslation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma.Small genomic insertions form enhancers that misregulate oncogenesTargeting the hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cellsstringgaussnet: from differentially expressed genes to semantic and Gaussian networks generation.Pigmented Lesions of the Nervous System and the Neural Crest: Lessons From Embryology.Identification of cis-regulatory mutations generating de novo edges in personalized cancer gene regulatory networksGenetic progression of malignant melanoma.NFATc2 is an intrinsic regulator of melanoma dedifferentiation.YAP/TAZ at the Roots of Cancer.Metastatic melanoma moves on: translational science in the era of personalized medicine.Focus on cutaneous and uveal melanoma specificities.Immune surveillance in melanoma: From immune attack to melanoma escape and even counterattack.Beyond MITF: Multiple transcription factors directly regulate the cellular phenotype in melanocytes and melanoma.Multiplex enhancer-reporter assays uncover unsophisticated TP53 enhancer logic.i-cisTarget 2015 update: generalized cis-regulatory enrichment analysis in human, mouse and fly.Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failureRare cell variability and drug-induced reprogramming as a mode of cancer drug resistance.Regulation of the Hippo Pathway Transcription Factor TEAD.Intratumor and Intertumor Heterogeneity in Melanoma.low neurotrophin receptor CD271 regulates phenotype switching in melanoma.SOX10-MITF pathway activity in melanoma cells.Genes uniquely expressed in human growth plate chondrocytes uncover a distinct regulatory network.Yorkie regulates epidermal wound healing in Drosophila larvae independently of cell proliferation and apoptosis.The emerging role of Hippo signaling pathway in regulating osteoclast formation.Harnessing BET Inhibitor Sensitivity Reveals AMIGO2 as a Melanoma Survival Gene.
P2860
Q26783032-A686071F-0B56-4CDB-B4EC-43A7995BF602Q28069018-E08DFED1-99DB-4B36-BA31-DE51B959F0EEQ30838636-0063B353-3D46-4D01-9023-5600A7860918Q33809465-577C1B91-9F8B-43AC-A1FC-7411AA97D4D0Q35530039-D3B930AA-2EBB-49E6-B83C-D7AD19E79F7CQ35752339-EB2EA30F-E20E-4035-B4CE-C2691B2BEFC9Q35840001-A21BA9DA-D425-429F-801C-02A5136E15E8Q36291579-B4C90946-28CF-4C51-844D-090E01E09EE8Q36320144-D7FFCA31-E85D-4C07-BADA-7322BB7F3058Q36381496-DB8C7499-BAF5-4B4E-95D3-575FB681BBE4Q36568116-B44F47F2-A4A7-4627-BD23-A8AB1AAC4364Q37046471-4A859856-AE86-449F-AA72-8BF55ECAE015Q37056708-1D7EB759-4C5F-4FE4-826C-56D55D7DD296Q37307458-758E7491-B878-46C1-81A1-D5BE544441AAQ37545749-16CF2A96-3ECB-4AD3-BCBB-698F4B02DF00Q37618946-6F40B2BD-A2A8-449F-946F-45F4A65439ACQ37642694-A87B1B50-020E-41C5-BDBC-3FEAE2591ADFQ37736262-46A4D855-CF8E-42C2-8758-C360D9B9F75DQ38406916-B0A4F53F-35DA-4FEF-A4B1-7B8D2F46E9BDQ38583968-09724963-9561-4630-9108-B9567B988633Q38601823-EE5C6CCD-D697-4DF3-936F-4EF62CEAFB20Q38771870-097927F6-684F-48CF-90FD-FAB00495B201Q38834040-88933E91-3D9D-4B81-A172-8B80E8044DB0Q38864941-2ED15355-405C-4ED5-8BA7-3D1BAACA5788Q38891959-842F2D50-68E4-4FE5-8AD1-2B00E9FF6DCAQ39312161-A1094016-40BD-4521-BE61-192919A0BC1EQ39312652-A7841D82-9258-4CC2-B37C-DAB955A142F5Q39397994-0907A18D-367D-4741-AB96-2DA015A16247Q39752696-1D08EE0D-873B-47BF-98A5-A5B7D0E92972Q40996671-F4A19749-FF0E-43E2-B944-DD56A28C0D9EQ41198115-1F742CEF-E5B1-4E1F-A7D7-9F4267C1BC94Q45347095-F88848F4-A2B4-4DB4-BB4E-B3B7948E1482Q46092496-8EF401FF-DF10-460C-B433-5F4CC9CEE3F8Q46742817-FB4F9895-6187-4F46-BBB8-C00CCB740611Q47103221-C18F5F4E-6097-46DE-A16E-5B4F7A48B763Q47104368-9156C451-45DD-4E83-AD1B-53B0926B5E20Q47147634-306D1220-8D9E-4790-956A-0858A8E44978Q47149836-7949F5E9-1830-4B61-BD51-490449F3F971Q47316032-2BD660FA-EDC6-4F30-B083-7DD2728E1881Q47391313-51AFB113-61E0-4335-83AB-3394EE7CCAEF
P2860
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state.
description
2015 nî lūn-bûn
@nan
2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Decoding the regulatory landsc ...... rs of the invasive cell state.
@ast
Decoding the regulatory landsc ...... rs of the invasive cell state.
@en
type
label
Decoding the regulatory landsc ...... rs of the invasive cell state.
@ast
Decoding the regulatory landsc ...... rs of the invasive cell state.
@en
prefLabel
Decoding the regulatory landsc ...... rs of the invasive cell state.
@ast
Decoding the regulatory landsc ...... rs of the invasive cell state.
@en
P2093
P2860
P50
P356
P1476
Decoding the regulatory landsc ...... rs of the invasive cell state.
@en
P2093
Annelien Verfaillie
Dmitry Svetlichnyy
Fabrice Journe
Flavie Luciani
Florian Rambow
Ghanem-Elias Ghanem
Laura Van den Mooter
Mark Fiers
Michael Dewaele
Valerie Christiaens
P2860
P2888
P356
10.1038/NCOMMS7683
P407
P50
P577
2015-04-09T00:00:00Z