Maf1 is a novel target of PTEN and PI3K signaling that negatively regulates oncogenesis and lipid metabolism
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Emerging Roles for Maf1 beyond the Regulation of RNA Polymerase III ActivityThe C-Box Region of MAF1 Regulates Transcriptional Activity and Protein Stability.Regulating maf1 expression and its expanding biological functions.Loss of the RNA polymerase III repressor MAF1 confers obesity resistance.A fluorescent bimolecular complementation screen reveals MAF1, RNF7 and SETD3 as PCNA-associated proteins in human cellsRNA Polymerase III Output Is Functionally Linked to tRNA Dimethyl-G26 Modification.Mechanistically linked serum miRNAs distinguish between drug induced and fatty liver disease of different gradesHuman MAF1 targets and represses active RNA polymerase III genes by preventing recruitment rather than inducing long-term transcriptional arrest.RNA Polymerase III Advances: Structural and tRNA Functional Views.Stress resistance and lifespan are increased in C. elegans but decreased in S. cerevisiae by mafr-1/maf1 deletion.MAF1 suppresses AKT-mTOR signaling and liver cancer through activation of PTEN transcription.Epithelialization of mouse ovarian tumor cells originating in the fallopian tube stroma.Wnt/β-catenin activation and macrophage induction during liver cancer development following steatosis.Maf1, A New PTEN Target Linking RNA and Lipid Metabolism.Maf1 is a negative regulator of transcription in Trypanosoma brucei.Elevated TATA-binding protein expression drives vascular endothelial growth factor expression in colon cancer.Low RNA Polymerase III activity results in up regulation of HXT2 glucose transporter independently of glucose signaling and despite changing environment.Correction: Maf1 is a novel target of PTEN and PI3K signaling that negatively regulates oncogenesis and lipid metabolism.PTEN Physically Interacts with and Regulates E2F1-mediated Transcription in Lung Cancer.Maf1 phenotypes and cell physiology.Signaling to and from the RNA Polymerase III Transcription and Processing Machinery.Lack of Maf1 enhances pyruvate kinase activity and fermentative metabolism while influencing lipid homeostasis in Saccharomyces cerevisiae.DNA methylation and the epigenetic clock in relation to physical frailty in older people: the Lothian Birth Cohort 1936Brain metabolic and functional alterations in a liver-specific PTEN knockout mouse modelMaf1 and Repression of RNA Polymerase III-Mediated Transcription Drive Adipocyte Differentiation
P2860
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P2860
Maf1 is a novel target of PTEN and PI3K signaling that negatively regulates oncogenesis and lipid metabolism
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Maf1 is a novel target of PTEN ...... cogenesis and lipid metabolism
@ast
Maf1 is a novel target of PTEN ...... cogenesis and lipid metabolism
@en
type
label
Maf1 is a novel target of PTEN ...... cogenesis and lipid metabolism
@ast
Maf1 is a novel target of PTEN ...... cogenesis and lipid metabolism
@en
prefLabel
Maf1 is a novel target of PTEN ...... cogenesis and lipid metabolism
@ast
Maf1 is a novel target of PTEN ...... cogenesis and lipid metabolism
@en
P2093
P2860
P1433
P1476
Maf1 is a novel target of PTEN ...... cogenesis and lipid metabolism
@en
P2093
Aarti D Rohira
Bangyan L Stiles
Beth M Palian
Deborah L Johnson
Louis Dubeau
Sandra A S Johnson
P2860
P304
P356
10.1371/JOURNAL.PGEN.1004789
P577
2014-12-11T00:00:00Z