The Lowe syndrome protein OCRL1 is required for endocytosis in the zebrafish pronephric tubule.
about
The fast-recycling receptor Megalin defines the apical recycling pathway of epithelial cells.Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction.Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRLReceptor-Mediated Endocytosis in the Proximal Tubule.The 5-phosphatase OCRL in Lowe syndrome and Dent disease 2.Glomerular Pathology in Dent Disease and Its Association with Kidney Function.Functional Characterization and Rescue of a Deep Intronic Mutation in OCRL Gene Responsible for Lowe Syndrome.dOCRL maintains immune cell quiescence by regulating endosomal traffic.Kidney-differentiated cells derived from Lowe Syndrome patient's iPSCs show ciliogenesis defects and Six2 retention at the Golgi complex.PALLD Regulates Phagocytosis by Enabling Timely Actin Polymerization and Depolymerization.Kidney Tubular Ablation of Ocrl/Inpp5b Phenocopies Lowe Syndrome Tubulopathy.Decreased urinary excretion of the ectodomain form of megalin (A-megalin) in children with OCRL gene mutations.Genetic Renal Diseases: The Emerging Role of Zebrafish Models
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P2860
The Lowe syndrome protein OCRL1 is required for endocytosis in the zebrafish pronephric tubule.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
The Lowe syndrome protein OCRL ...... e zebrafish pronephric tubule.
@ast
The Lowe syndrome protein OCRL ...... e zebrafish pronephric tubule.
@en
type
label
The Lowe syndrome protein OCRL ...... e zebrafish pronephric tubule.
@ast
The Lowe syndrome protein OCRL ...... e zebrafish pronephric tubule.
@en
prefLabel
The Lowe syndrome protein OCRL ...... e zebrafish pronephric tubule.
@ast
The Lowe syndrome protein OCRL ...... e zebrafish pronephric tubule.
@en
P2093
P2860
P1433
P1476
The Lowe syndrome protein OCRL ...... he zebrafish pronephric tubule
@en
P2093
Aleksandr Mironov
Grzegorz Pietka
Iain A Drummond
Irene Barinaga-Rementeria Ramirez
Katherine A Hinchliffe
Martin Lowe
Toby Starborg
P2860
P304
P356
10.1371/JOURNAL.PGEN.1005058
P577
2015-04-02T00:00:00Z