Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer. - Wikidata - thesis-toulmin - TriplyDB

Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer.

Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer.

http://www.wikidata.org/entity/Q35600870

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Notch Signaling in Neuroendocrine Tumors Emerging Role of Genomic Rearrangements in Breast Cancer: Applying Knowledge from Other Cancers Revealing the Complexity of Breast Cancer by Next Generation Sequencing Notch signaling in prostate cancer: refining a therapeutic opportunity From integrative genomics to therapeutic targets Notch signaling in prostate cancer: a moving target Targeting γ-secretase in breast cancer From fly wings to targeted cancer therapies: a centennial for notch signaling Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies Identification of targetable FGFR gene fusions in diverse cancers.Appraisal of the technologies and review of the genomic landscape of ductal carcinoma in situ of the breast Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types Proteomic Analysis of Urine to Identify Breast Cancer Biomarker Candidates Using a Label-Free LC-MS/MS Approach cDNA hybrid capture improves transcriptome analysis on low-input and archived samples Biomarkers of genome instability and cancer epigenetics.An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma.Discovery of biomarkers predictive of GSI response in triple-negative breast cancer and adenoid cystic carcinoma.Reanalysis of RNA-sequencing data reveals several additional fusion genes with multiple isoforms.The Drosophila MAST kinase Drop out is required to initiate membrane compartmentalisation during cellularisation and regulates dynein-based transport Exploration of the gene fusion landscape of glioblastoma using transcriptome sequencing and copy number data Discovery of prognostic biomarkers for predicting lung cancer metastasis using microarray and survival data.FusionCancer: a database of cancer fusion genes derived from RNA-seq data.Decoding breast cancer tissue-stroma interactions using species-specific sequencing INTEGRATE: gene fusion discovery using whole genome and transcriptome data.Discovering and understanding oncogenic gene fusions through data intensive computational approaches Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing.Characterization of the genomic features and expressed fusion genes in micropapillary carcinomas of the breast.Targeting Met and Notch in the Lfng-deficient, Met-amplified triple-negative breast cancer.Identifying the structure-activity relationship of leelamine necessary for inhibiting intracellular cholesterol transport.BreakTrans: uncovering the genomic architecture of gene fusions Recurrent read-through fusion transcripts in breast cancer.Integrative analysis of genomic alterations in triple-negative breast cancer in association with homologous recombination deficiency.Triple-negative breast cancer: the importance of molecular and histologic subtyping, and recognition of low-grade variants.Sequence analysis of mutations and translocations across breast cancer subtypes Recurrent ESR1-CCDC170 rearrangements in an aggressive subset of oestrogen receptor-positive breast cancers.Landscape of somatic mutations in 560 breast cancer whole-genome sequences.Cancer genomics and pathology: all together now.Notch inhibitors for cancer treatment.Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia Structural analysis of the genome of breast cancer cell line ZR-75-30 identifies twelve expressed fusion genes.

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P2860

Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer.

http://www.wikidata.org/entity/Q35600870

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Functionally recurrent rearran ...... ene families in breast cancer.

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Functionally recurrent rearran ...... ene families in breast cancer.

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Nature Medicine

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Functionally recurrent rearran ...... ene families in breast cancer.

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Arul M Chinnaiyan

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Catherine S Grasso

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Celina G Kleer

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Christopher A Maher

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Dan R Robinson

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Javed Siddiqui

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Maryou B Lambros

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Matthew Iyer

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Michael Quist

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Michael S Sabel

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P2860

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

Complex landscapes of somatic rearrangement in human breast cancer genomes.

Transcriptome sequencing to detect gene fusions in cancer

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

Genome remodelling in a basal-like breast cancer metastasis and xenograft

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells

Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma.

Chromosome studies on normal and leukemic human leukocytes.

Oncogenic gene fusions in epithelial carcinomas

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10.1038/NM.2580

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12

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17

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Jorge Reis-Filho

Rachael Natrajan

Thomas Giordano

Nallasivam Palanisamy

Chandan Kumar-Sinha

Shanker Kalyana-Sundaram

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2011-11-20T00:00:00Z

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51815968

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22101766

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3233654

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