Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival.
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Insights into the Regulatory Role of Non-coding RNAs in Cancer MetabolismWhole-genome analysis of papillary kidney cancer finds significant noncoding alterationsThe clinical value of lncRNA NEAT1 in digestive system malignancies: A comprehensive investigation based on 57 microarray and RNA-seq datasets.Functional dissection of NEAT1 using genome editing reveals substantial localization of the NEAT1_1 isoform outside paraspeckles.Insights from Global Analyses of Long Noncoding RNAs in Breast CancerOct4 transcriptionally regulates the expression of long non-coding RNAs NEAT1 and MALAT1 to promote lung cancer progression.Long non-coding RNA expression profiles predict metastasis in lymph node-negative breast cancer independently of traditional prognostic markersClinical implication of long non-coding RNA NEAT1 expression in hepatocellular carcinoma patientsPredicting lncRNA-disease associations and constructing lncRNA functional similarity network based on the information of miRNALong noncoding RNAs: Re-writing dogmas of RNA processing and stability.RANTES mediates kidney ischemia reperfusion injury through a possible role of HIF-1α and LncRNA PRINS.TP53 regulates miRNA association with AGO2 to remodel the miRNA-mRNA interaction networkNoncoding RNAs in breast cancer.Long noncoding RNA ANRIL is activated by hypoxia-inducible factor-1α and promotes osteosarcoma cell invasion and suppresses cell apoptosis upon hypoxiaParaspeckles modulate the intranuclear distribution of paraspeckle-associated Ctn RNA.Induction of long noncoding RNA MALAT1 in hypoxic miceNEAT1 upregulates EGCG-induced CTR1 to enhance cisplatin sensitivity in lung cancer cells.IntNetLncSim: an integrative network analysis method to infer human lncRNA functional similarity.Prognostic role of long noncoding RNA NEAT1 in various carcinomas: a meta-analysis.Dysregulation of the BRCA1/long non-coding RNA NEAT1 signaling axis contributes to breast tumorigenesis.Long non-coding RNA and tumor hypoxia: new players ushered toward an old arena.Influence of the interaction between long noncoding RNAs and hypoxia on tumorigenesis.Long noncoding RNAs: emerging regulators of tumor angiogenesis.Neat1 is a p53-inducible lincRNA essential for transformation suppression.Cytoglobin inhibits migration through PI3K/AKT/mTOR pathway in fibroblast cells.p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity.Long noncoding RNA NEAT1 is an unfavorable prognostic factor and regulates migration and invasion in gastric cancer.Remodelling of microRNAs in colorectal cancer by hypoxia alters metabolism profiles and 5-fluorouracil resistance.Long Noncoding RNAs: At the Intersection of Cancer and Chromatin Biology.NEAT1 scaffolds RNA-binding proteins and the Microprocessor to globally enhance pri-miRNA processing.NEAT1 accelerates the progression of liver fibrosis via regulation of microRNA-122 and Kruppel-like factor 6.Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer.CPSF6 is a Clinically Relevant Breast Cancer Vulnerability Target: Role of CPSF6 in Breast Cancer.Hypoxic regulation of the noncoding genome and NEAT1.Knockdown of Long Non-Coding RNA NEAT1 Inhibits Proliferation and Invasion and Induces Apoptosis of Osteosarcoma by Inhibiting miR-194 Expression.NEAT1 negatively regulates miR-218 expression and promotes breast cancer progression.Junctional Adhesion Molecules (JAMs): Cell Adhesion Receptors With Pleiotropic Functions in Cell Physiology and Development.HIF-2α activated lncRNA NEAT1 promotes hepatocellular carcinoma cell invasion and metastasis by affecting the epithelial-mesenchymal transition.Glycolysis gatekeeper PDK1 reprograms breast cancer stem cells under hypoxia.Altered Expression of the Long Noncoding RNA NEAT1 in Huntington's Disease.
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P2860
Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Tumor hypoxia induces nuclear ...... ading to cancer cell survival.
@ast
Tumor hypoxia induces nuclear ...... ading to cancer cell survival.
@en
type
label
Tumor hypoxia induces nuclear ...... ading to cancer cell survival.
@ast
Tumor hypoxia induces nuclear ...... ading to cancer cell survival.
@en
prefLabel
Tumor hypoxia induces nuclear ...... ading to cancer cell survival.
@ast
Tumor hypoxia induces nuclear ...... ading to cancer cell survival.
@en
P2093
P2860
P50
P356
P1433
P1476
Tumor hypoxia induces nuclear ...... eading to cancer cell survival
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2014.378
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P50
P577
2014-11-24T00:00:00Z