The SLC36 family of proton-coupled amino acid transporters and their potential role in drug transport
about
Conserved regulators of Rag GTPases orchestrate amino acid-dependent TORC1 signalingOntogenetic differences in localization of glutamine transporter ApGLNT1 in the pea aphid demonstrate that mechanisms of host/symbiont integration are not similar in the maternal versus embryonic bacteriome.The Concise Guide to PHARMACOLOGY 2013/14: transporters.Amino acid homeostasis and signalling in mammalian cells and organisms.Proton-assisted amino acid transporter PAT1 complexes with Rag GTPases and activates TORC1 on late endosomal and lysosomal membranes.Transport of the areca nut alkaloid arecaidine by the human proton-coupled amino acid transporter 1 (hPAT1).Pemphigus vulgaris autoantibody profiling by proteomic technique.Placental accommodations for transport and metabolism during intra-uterine crowding in pigsThe SLC36 transporter Pathetic is required for extreme dendrite growth in Drosophila sensory neurons.Blood Transcriptomic Markers in Patients with Late-Onset Major Depressive DisorderFLCN Maintains the Leucine Level in Lysosome to Stimulate mTORC1.The emerging role of mTORC1 signaling in placental nutrient-sensingPAT4 levels control amino-acid sensitivity of rapamycin-resistant mTORC1 from the Golgi and affect clinical outcome in colorectal cancerSignificance of peptide transporter 1 in the intestinal permeability of valacyclovir in wild-type and PepT1 knockout mice.The position of lysosomes within the cell determines their luminal pHNutrient transporters: the Achilles' heel of anabolism.Gene Family Expansions in Aphids Maintained by Endosymbiotic and Nonsymbiotic TraitsProteome analysis and conditional deletion of the EAAT2 glutamate transporter provide evidence against a role of EAAT2 in pancreatic insulin secretion in mice.Targeted prodrugs in oral drug delivery: the modern molecular biopharmaceutical approach.Regulation of membrane trafficking by signalling on endosomal and lysosomal membranes.Protein transport across the small intestine in food allergy.Pharmacokinetic aspects of the anti-epileptic drug substance vigabatrin: focus on transporter interactions.Identification and validation of soluble carrier family expression signature for predicting poor outcome of renal cell carcinoma.Reconstitution of T Cell Proliferation under Arginine Limitation: Activated Human T Cells Take Up Citrulline via L-Type Amino Acid Transporter 1 and Use It to Regenerate Arginine after Induction of Argininosuccinate Synthase Expression.Preclinical Evaluation of 11C-Sarcosine as a Substrate of Proton-Coupled Amino Acid Transporters and First Human Application in Prostate Cancer.Glycosylation affects the stability and subcellular distribution of human PAT1 protein.Transport of L-proline by the proton-coupled amino acid transporter PAT2 in differentiated 3T3-L1 cells.Sertraline inhibits the transport of PAT1 substrates in vivo and in vitro.Intestinal absorption of the antiepileptic drug substance vigabatrin is altered by infant formula in vitro and in vivo.Transporters are an under-developed therapeutic target. Discuss.Amino acids suppress the expression of PAT1 on lysosomes via inducing the cleavage of a targeting signal.Gamma-aminobutyric acid (GABA) permeates ovine ruminal and jejunal epithelia, mainly by passive diffusion.Structural basis for amino acid transport by the CAT family of SLC7 transporters.Resculpting the binding pocket of APC superfamily LeuT-fold amino acid transporters.Modern prodrug design for targeted oral drug delivery.The Regulatory Role of MeAIB in Protein Metabolism and the mTOR Signaling Pathway in Porcine Enterocytes.Exploring the pathogenesis of canine epilepsy using a systems genetics method and implications for anti-epilepsy drug discovery.
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P2860
The SLC36 family of proton-coupled amino acid transporters and their potential role in drug transport
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The SLC36 family of proton-cou ...... tential role in drug transport
@ast
The SLC36 family of proton-cou ...... tential role in drug transport
@en
type
label
The SLC36 family of proton-cou ...... tential role in drug transport
@ast
The SLC36 family of proton-cou ...... tential role in drug transport
@en
prefLabel
The SLC36 family of proton-cou ...... tential role in drug transport
@ast
The SLC36 family of proton-cou ...... tential role in drug transport
@en
P2860
P1476
The SLC36 family of proton-cou ...... tential role in drug transport
@en
P2093
Catriona M H Anderson
David T Thwaites
P2860
P304
P356
10.1111/J.1476-5381.2011.01438.X
P407
P577
2011-12-01T00:00:00Z