D-amino acid oxidase controls motoneuron degeneration through D-serine. - Wikidata - thesis-toulmin - TriplyDB

D-amino acid oxidase controls motoneuron degeneration through D-serine.

D-amino acid oxidase controls motoneuron degeneration through D-serine.

http://www.wikidata.org/entity/Q35673702

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Recent progress in the discovery of small molecules for the treatment of amyotrophic lateral sclerosis (ALS)Control of Appetite and Food Preference by NMDA Receptor and Its Co-Agonist d-Serine Chronic Glutamate Toxicity in Neurodegenerative Diseases-What is the Evidence?Peroxisomes in brain development and function The role of D-serine and glycine as co-agonists of NMDA receptors in motor neuron degeneration and amyotrophic lateral sclerosis (ALS)Serine racemase: a key player in apoptosis and necrosis Cell-type specific mechanisms of D-serine uptake and release in the brain Activity of D-amino acid oxidase is widespread in the human central nervous system.Heterogeneity of D-Serine Distribution in the Human Central Nervous System.The role of D-amino acids in amyotrophic lateral sclerosis pathogenesis: a review.Cellular origin and regulation of D- and L-serine in in vitro and in vivo models of cerebral ischemia.Study on a Single-Dose Toxicity Test of D-Amino Acid Oxidase (DAAO) Extracts Injected into the Tail Vein of Rats.Positional plasticity in regenerating Amybstoma mexicanum limbs is associated with cell proliferation and pathways of cellular differentiation.D-Serine Production, Degradation, and Transport in ALS: Critical Role of Methodology Chiral amino acid metabolomics for novel biomarker screening in the prognosis of chronic kidney disease.D-serine in the midbrain periaqueductal gray contributes to morphine tolerance in rats.Genetics of amyotrophic lateral sclerosis: an update.Interplay between microbial d-amino acids and host d-amino acid oxidase modifies murine mucosal defence and gut microbiota.Overdose of D-serine Induces Movement Disorder and Neuromuscular Changes of Zebrafish Larvae.The peroxisome: an update on mysteries.Amperometric microbiosensor as an alternative tool for investigation of D-serine in brain.D-Amino acids in the brain and mutant rodents lacking D-amino-acid oxidase activity.The multifaceted role of glial cells in amyotrophic lateral sclerosis.Amyotrophic lateral sclerosis: an update on recent genetic insights.The role of D-serine as co-agonist of NMDA receptors in the nucleus accumbens: relevance to cocaine addiction.Astrocytes in neurodegenerative disease.Transcriptional analysis reveals distinct subtypes in amyotrophic lateral sclerosis: implications for personalized therapy.Taurine Protects Glutamate Neurotoxicity in Motor Neuron Cells.Disruption of TCA Cycle and Glutamate Metabolism Identified by Metabolomics in an In Vitro Model of Amyotrophic Lateral Sclerosis.D-Amino Acids in the Nervous and Endocrine Systems.RNA-binding proteins with prion-like domains in health and disease.Intrathecal Delivery of ssAAV9-DAO Extends Survival in SOD1G93A ALS Mice.Intramuscular Delivery of scAAV9-hIGF1 Prolongs Survival in the hSOD1G93A ALS Mouse Model via Upregulation of D-Amino Acid Oxidase.Ischemic acute kidney injury perturbs homeostasis of serine enantiomers in the body fluid in mice: early detection of renal dysfunction using the ratio of serine enantiomers.Blood levels of D-amino acid oxidase vs. D-amino acids in reflecting cognitive aging.Musculotopic organization of the motor neurons supplying the mouse hindlimb muscles: a quantitative study using Fluoro-Gold retrograde tracing.Mouse d-Amino-Acid Oxidase: Distribution and Physiological Substrates.Characterisation of the pathogenic effects of the in vivo expression of an ALS-linked mutation in D-amino acid oxidase: Phenotype and loss of spinal cord motor neurons.Disrupted-in-schizophrenia-1 as a broader link of glutamatergic transmission to schizophrenia impacts cerebral neurochemistry via the production of the 'gliotransmitter' d-serine, a NMDA receptor coagonist.N-methyl-d-aspartate receptor coagonist d-serine suppresses intake of high-preference food.

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P2860

D-amino acid oxidase controls motoneuron degeneration through D-serine.

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D-amino acid oxidase controls motoneuron degeneration through D-serine.

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D-amino acid oxidase controls motoneuron degeneration through D-serine.

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D-amino acid oxidase controls motoneuron degeneration through D-serine.

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D-amino acid oxidase controls motoneuron degeneration through D-serine.

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D-amino acid oxidase controls motoneuron degeneration through D-serine.

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D-amino acid oxidase controls motoneuron degeneration through D-serine.

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Proceedings of the National Academy of Sciences of the United States of America

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D-amino acid oxidase controls motoneuron degeneration through D-serine.

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Jumpei Sasabe

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Kenji Hamase

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Masaaki Matsuoka

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Masashi Mita

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Masataka Suzuki

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Ryuichi Konno

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Sadakazu Aiso

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Yurika Miyoshi

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P2860

Characterization of human D-amino acid oxidase

Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B

D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor

Characterisation of the expression of NMDA receptors in human astrocytes

Glia-derived D-serine controls NMDA receptor activity and synaptic memory

Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

Unraveling the mechanisms involved in motor neuron degeneration in ALS

Targeted disruption of serine racemase affects glutamatergic neurotransmission and behavior

An electron microscopic examination of the corticospinal projection to the cervical spinal cord in the rat: lack of evidence for cortico-motoneuronal synapses.

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