Defining the Roles of TcdA and TcdB in Localized Gastrointestinal Disease, Systemic Organ Damage, and the Host Response during Clostridium difficile Infections
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Clostridium difficile Toxins A and B: Insights into Pathogenic Properties and Extraintestinal EffectsUltrasensitive Detection and Quantification of Toxins for Optimized Diagnosis of Clostridium difficile InfectionImportance of Glutamate Dehydrogenase (GDH) in Clostridium difficile Colonization In VivoThe binary toxin CDT enhances Clostridium difficile virulence by suppressing protective colonic eosinophilia.Glucosylation Drives the Innate Inflammatory Response to Clostridium difficile Toxin AFrizzled proteins are colonic epithelial receptors for C. difficile toxin B.Novel Clostridium difficile Anti-Toxin (TcdA and TcdB) Humanized Monoclonal Antibodies Demonstrate In Vitro Neutralization across a Broad Spectrum of Clinical Strains and In Vivo Potency in a Hamster Spore Challenge ModelCdtR Regulates TcdA and TcdB Production in Clostridium difficileClostridium difficile colitis: pathogenesis and host defenceClostridium difficile Toxin A Undergoes Clathrin-Independent, PACSIN2-Dependent EndocytosisA genetic switch controls the production of flagella and toxins in Clostridium difficileRegulation of Clostridium difficile spore germination by the CspA pseudoprotease domainAnalysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities.Screening of Bifidobacteria and Lactobacilli Able to Antagonize the Cytotoxic Effect of Clostridium difficile upon Intestinal Epithelial HT29 Monolayer.Surviving Between Hosts: Sporulation and Transmission.Bacterial glycosyltransferase toxins.Immunization with Recombinant TcdB-Encapsulated Nanocomplex Induces Protection against Clostridium difficile Challenge in a Mouse Model.Recombinant Mucin-Type Fusion Proteins with a Galα1,3Gal Substitution as Clostridium difficile Toxin A Inhibitors.Pathogenic effects of glucosyltransferase from Clostridium difficile toxins.Host response to Clostridium difficile infection: Diagnostics and detection.Current knowledge on the laboratory diagnosis of Clostridium difficile infection.Bovine antibodies targeting primary and recurrent Clostridium difficile disease are a potent antibiotic alternative.Clostridium difficile Toxins TcdA and TcdB Cause Colonic Tissue Damage by Distinct Mechanisms.SNP-ing out the differences: Investigating differences between Clostridium difficile lab strains.Prevalence of binary toxin positive Clostridium difficile in diarrhoeal humans in the absence of epidemic ribotype 027.Fidaxomicin and OP-1118 inhibit C. difficile toxin A- and B-mediated inflammatory responses via inhibition of NF-κB activity.Inactivation of the dnaK gene in Clostridium difficile 630 Δerm yields a temperature-sensitive phenotype and increases biofilm-forming ability.A neutralizing antibody that blocks delivery of the enzymatic cargo of Clostridium difficile toxin TcdB into host cells.The role of toxins in Clostridium difficile infection.The role of purified Clostridium difficile glucosylating toxins in disease pathogenesis utilizing a murine cecum injection model.GeneGini: Assessment via the Gini Coefficient of Reference "Housekeeping" Genes and Diverse Human Transporter Expression Profiles.Treatment of recurrent Clostridium difficile colitis: a narrative review.Clostridium difficile Toxins A and B Decrease Intestinal SLC26A3 Protein Expression.A Rapid, Accurate, Single Molecule Counting Method Detects Clostridium difficile Toxin B in Stool Samples.Thirty-Day Readmissions in Hospitalized Patients Who Received Bezlotoxumab With Antibacterial Drug Treatment for Clostridium difficile Infection.Clostridium sordellii outer spore proteins maintain spore structural integrity and promote bacterial clearance from the gastrointestinal tract.Cysteine Protease-Mediated Autocleavage of Clostridium difficile Toxins Regulates Their Proinflammatory Activity.Protective Effects of Bifidobacterial Strains Against Toxigenic Clostridium difficile.Effect of the Synthetic Bile Salt Analog CamSA on the Hamster Model of Clostridium difficile InfectionNovel Clade C-I Clostridium difficile strains escape diagnostic tests, differ in pathogenicity potential and carry toxins on extrachromosomal elements
P2860
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P2860
Defining the Roles of TcdA and TcdB in Localized Gastrointestinal Disease, Systemic Organ Damage, and the Host Response during Clostridium difficile Infections
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Defining the Roles of TcdA and ...... ostridium difficile Infections
@ast
Defining the Roles of TcdA and ...... ostridium difficile Infections
@en
type
label
Defining the Roles of TcdA and ...... ostridium difficile Infections
@ast
Defining the Roles of TcdA and ...... ostridium difficile Infections
@en
prefLabel
Defining the Roles of TcdA and ...... ostridium difficile Infections
@ast
Defining the Roles of TcdA and ...... ostridium difficile Infections
@en
P2093
P2860
P50
P356
P1433
P1476
Defining the Roles of TcdA and ...... ostridium difficile Infections
@en
P2093
Adam Cheknis
Anjana Chakravorty
Dale Gerding
Fernanda Schreiber
Gordon Dougan
Iris Figueroa
Pauline Howarth
Simon Clare
Stuart Johnson
P2860
P304
P356
10.1128/MBIO.00551-15
P577
2015-06-02T00:00:00Z