Mammary gland specific expression of Brk/PTK6 promotes delayed involution and tumor formation associated with activation of p38 MAPK.
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Cancer-Associated Mutations in Breast Tumor Kinase/PTK6 Differentially Affect Enzyme Activity and Substrate Recognition.Evolution of breast cancer therapeutics: Breast tumour kinase's role in breast cancer and hope for breast tumour kinase targeted therapyMechanisms of HGF/Met signaling to Brk and Sam68 in breast cancer progression.PTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors.Breast tumor kinase (Brk/PTK6) is a mediator of hypoxia-associated breast cancer progression.BRK targets Dok1 for ubiquitin-mediated proteasomal degradation to promote cell proliferation and migration.Constitutive activation of breast tumor kinase accelerates cell migration and tumor growth in vivo.Breast Tumor Kinase (Brk/PTK6) Is Induced by HIF, Glucocorticoid Receptor, and PELP1-Mediated Stress Signaling in Triple-Negative Breast CancerProtein tyrosine kinase 6 regulates mammary gland tumorigenesis in mouse models.Context-specific protein tyrosine kinase 6 (PTK6) signalling in prostate cancer.Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT.Validating whole slide digital morphometric analysis as a microscopy tool.Downregulated expression of PTK6 is correlated with poor survival in esophageal squamous cell carcinoma.
P2860
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P2860
Mammary gland specific expression of Brk/PTK6 promotes delayed involution and tumor formation associated with activation of p38 MAPK.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Mammary gland specific express ...... d with activation of p38 MAPK.
@ast
Mammary gland specific express ...... d with activation of p38 MAPK.
@en
type
label
Mammary gland specific express ...... d with activation of p38 MAPK.
@ast
Mammary gland specific express ...... d with activation of p38 MAPK.
@en
prefLabel
Mammary gland specific express ...... d with activation of p38 MAPK.
@ast
Mammary gland specific express ...... d with activation of p38 MAPK.
@en
P2093
P2860
P356
P1476
Mammary gland specific express ...... d with activation of p38 MAPK.
@en
P2093
Alessia Locatelli
Carol A Lange
Daniel Housa
Gregory K Hubbard
Julie H Ostrander
Kathryn L Schwertfeger
Kristopher A Lofgren
Robin L Bliss
P2860
P2888
P356
10.1186/BCR2946
P577
2011-09-17T00:00:00Z
P5875
P6179
1047774258