Rab27b regulates number and secretion of platelet dense granules. - Wikidata - thesis-toulmin - TriplyDB

Rab27b regulates number and secretion of platelet dense granules.

Rab27b regulates number and secretion of platelet dense granules.

http://www.wikidata.org/entity/Q35696422

about

Small Rab GTPase Rab7b promotes megakaryocytic differentiation by enhancing IL-6 production and STAT3-GATA-1 association Germline Mutation in EXPH5 Implicates the Rab27B Effector Protein Slac2-b in Inherited Skin Fragility WNT-3a modulates platelet function by regulating small GTPase activity Regulation of vesicular trafficking and leukocyte function by Rab27 GTPases and their effectors Direct imaging of RAB27B-enriched secretory vesicle biogenesis in lacrimal acinar cells reveals origins on a nascent vesicle budding site Rab-mediated vesicle trafficking in cancer Platelet Shape Changes and Cytoskeleton Dynamics as Novel Therapeutic Targets for Anti-Thrombotic Drugs Immunomodulatory effects mediated by serotonin Megakaryopoiesis and platelet production: insight into hematopoietic stem cell proliferation and differentiation Rac1 Regulates Endometrial Secretory Function to Control Placental Development Rab27b regulates exocytosis of secretory vesicles in acinar epithelial cells from the lacrimal gland.Imbalanced Rab3D versus Rab27 increases cathepsin S secretion from lacrimal acini in a mouse model of Sjögren's Syndrome.Macrothrombocytopenia and dense granule deficiency associated with FLI1 variants: ultrastructural and pathogenic features.Inherited platelet disorders: a clinical approach to diagnosis and management.Mechanisms underlying platelet function defect in a pedigree with familial platelet disorder with a predisposition to acute myelogenous leukemia: potential role for candidate RUNX1 targets.Endobrevin/VAMP-8-dependent dense granule release mediates thrombus formation in vivo Loss-of-function mutations in Rab escort protein 1 (REP-1) affect intracellular transport in fibroblasts and monocytes of choroideremia patients The nuts and bolts of the platelet release reaction.Thousands of rab GTPases for the cell biologist.Munc13-4 is a limiting factor in the pathway required for platelet granule release and hemostasis.Rab27a and Rab27b regulate neutrophil azurophilic granule exocytosis and NADPH oxidase activity by independent mechanisms.Platelet secretion and hemostasis require syntaxin-binding protein STXBP5.Rab GTPase mediated procollagen trafficking in ascorbic acid stimulated osteoblasts.A role for Rab27 in neutrophil chemotaxis and lung recruitment.Global ablation of the mouse Rab11a gene impairs early embryogenesis and matrix metalloproteinase secretion.Absence of platelet phenotype in mice lacking the motor protein myosin Va The secretory small GTPase Rab27B as a marker for breast cancer progression.Loss of Rab27 function results in abnormal lung epithelium structure in mice.Distinct roles for Rap1b protein in platelet secretion and integrin αIIbβ3 outside-in signaling Involvement of vps33a in the fusion of uroplakin-degrading multivesicular bodies with lysosomes Microglial migration mediated by ATP-induced ATP release from lysosomes Rab27b is expressed in a wide range of exocytic cells and involved in the delivery of secretory granules near the plasma membrane.Rab27b regulates mast cell granule dynamics and secretion.Munc18b/STXBP2 is required for platelet secretion.Primary platelet signaling cascades and integrin-mediated signaling control ADP-ribosylation factor (Arf) 6-GTP levels during platelet activation and aggregation.The class V myosin motor, myosin 5c, localizes to mature secretory vesicles and facilitates exocytosis in lacrimal acini Sequential and compartmentalized action of Rabs, SNAREs, and MAL in the apical delivery of fusiform vesicles in urothelial umbrella cells Role of Rab27 in synaptic transmission at the squid giant synapse EPI64B acts as a GTPase-activating protein for Rab27B in pancreatic acinar cells Multiple Rab GTPase binding sites in GCC185 suggest a model for vesicle tethering at the trans-Golgi.

P2860

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P2860

Rab27b regulates number and secretion of platelet dense granules.

http://www.wikidata.org/entity/Q35696422

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

Rab27b regulates number and secretion of platelet dense granules.

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Rab27b regulates number and secretion of platelet dense granules.

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type

label

Rab27b regulates number and secretion of platelet dense granules.

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Rab27b regulates number and secretion of platelet dense granules.

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prefLabel

Rab27b regulates number and secretion of platelet dense granules.

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Rab27b regulates number and secretion of platelet dense granules.

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Rab27b regulates number and secretion of platelet dense granules.

@en

P2093

Kalwant S Authi

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Magnus Abrink

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Tanya Tolmachova

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P2860

Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development

Functional redundancy of Rab27 proteins and the pathogenesis of Griscelli syndrome

Central role of the P2Y12 receptor in platelet activation

Novel Munc13-4 mutations in children and young adult patients with haemophagocytic lymphohistiocytosis

Rab proteins as membrane organizers

Evolution of the Rab family of small GTP-binding proteins

Rab27b localizes to zymogen granules and regulates pancreatic acinar exocytosis

A mutation in Rab27a causes the vesicle transport defects observed in ashen mice

Rabs and their effectors: achieving specificity in membrane traffic

Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome

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14

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104

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Miguel C. Seabra

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2007-03-23T00:00:00Z

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6423688

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