Protein misinteraction avoidance causes highly expressed proteins to evolve slowly
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Protein stickiness, rather than number of functional protein-protein interactions, predicts expression noise and plasticity in yeastCauses of evolutionary rate variation among protein sitesComparing protein folding in vitro and in vivo: foldability meets the fitness challengeLoss of quaternary structure is associated with rapid sequence divergence in the OSBS familySelection on Network Dynamics Drives Differential Rates of Protein Domain EvolutionDeterminants of the rate of protein sequence evolutionExperimental evolution of protein-protein interaction networksEvaluating the fitness cost of protein expression in Saccharomyces cerevisiae.Selection on protein structure, interaction, and sequence.Biophysical Models of Protein Evolution: Understanding the Patterns of Evolutionary Sequence Divergence.Independent effects of protein core size and expression on residue-level structure-evolution relationships.Residue mutations and their impact on protein structure and function: detecting beneficial and pathogenic changes.Protein biophysics explains why highly abundant proteins evolve slowlyThe ortholog conjecture is untestable by the current gene ontology but is supported by RNA sequencing data.Protein-protein binding selectivity and network topology constrain global and local properties of interface binding networks.Codon-by-codon modulation of translational speed and accuracy via mRNA folding.Evidence for widespread positive and negative selection in coding and conserved noncoding regions of Capsella grandiflora.Biophysics of protein evolution and evolutionary protein biophysicsPurifying selection on splice-related motifs, not expression level nor RNA folding, explains nearly all constraint on human lincRNAs.Evolutionary capacitance and control of protein stability in protein-protein interaction networks.Translational signatures and mRNA levels are highly correlated in human stably expressed genes.Testing whether metazoan tyrosine loss was driven by selection against promiscuous phosphorylation.Transcriptional abundance is not the single force driving the evolution of bacterial proteinsProtein folding and binding can emerge as evolutionary spandrels through structural coupling.Universal distribution of mutational effects on protein stability, uncoupling of protein robustness from sequence evolution and distinct evolutionary modes of prokaryotic and eukaryotic proteins.Characterizing selective pressures on the pathway for de novo biosynthesis of pyrimidines in yeastPolymorphism Analysis Reveals Reduced Negative Selection and Elevated Rate of Insertions and Deletions in Intrinsically Disordered Protein Regions.High expression hampers horizontal gene transfer.Genetic Variation of Goat Interferon Regulatory Factor 3 Gene and Its Implication in Goat Evolution.Adaptation of A-to-I RNA editing in Drosophila.Nascent RNA folding mitigates transcription-associated mutagenesisThe Roles of Compensatory Evolution and Constraint in Aminoacyl tRNA Synthetase Evolution.Expression Differentiation Is Constrained to Low-Expression Proteins over Ecological Timescales.Genomic evidence for elevated mutation rates in highly expressed genesCellular crowding imposes global constraints on the chemistry and evolution of proteomes.Differential requirements for mRNA folding partially explain why highly expressed proteins evolve slowly.Flagellated algae protein evolution suggests the prevalence of lineage-specific rules governing evolutionary rates of eukaryotic proteinsAbundance and Temperature Dependency of Protein-Protein Interaction Revealed by Interface Structure Analysis and Stability Evolution.Population size dependence of fitness effect distribution and substitution rate probed by biophysical model of protein thermostability.Complex Patterns of Association between Pleiotropy and Transcription Factor Evolution.
P2860
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P2860
Protein misinteraction avoidance causes highly expressed proteins to evolve slowly
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Protein misinteraction avoidance causes highly expressed proteins to evolve slowly
@ast
Protein misinteraction avoidance causes highly expressed proteins to evolve slowly
@en
type
label
Protein misinteraction avoidance causes highly expressed proteins to evolve slowly
@ast
Protein misinteraction avoidance causes highly expressed proteins to evolve slowly
@en
prefLabel
Protein misinteraction avoidance causes highly expressed proteins to evolve slowly
@ast
Protein misinteraction avoidance causes highly expressed proteins to evolve slowly
@en
P2093
P2860
P356
P1476
Protein misinteraction avoidance causes highly expressed proteins to evolve slowly
@en
P2093
Ben-Yang Liao
Jian-Rong Yang
Jianzhi Zhang
Shi-Mei Zhuang
P2860
P304
P356
10.1073/PNAS.1117408109
P407
P577
2012-03-13T00:00:00Z