Loss of Bmal1 leads to uncoupling and impaired glucose-stimulated insulin secretion in β-cells.
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Evidences of Polymorphism Associated with Circadian System and Risk of Pathologies: A Review of the LiteratureClock genes in hypertension: novel insights from rodent modelsDoes disruption of circadian rhythms contribute to beta-cell failure in type 2 diabetes?Circadian dysfunction may be a key component of the non-motor symptoms of Parkinson's disease: insights from a transgenic mouse modelCircadian regulation of metabolismCircadian System and Glucose Metabolism: Implications for Physiology and DiseaseClock genes, pancreatic function, and diabetesCarbohydrate response element-binding protein (ChREBP) plays a pivotal role in beta cell glucotoxicityMechanism of the circadian clock in physiology.Uncoupling protein 2 regulates daily rhythms of insulin secretion capacity in MIN6 cells and isolated islets from male miceAdvances in understanding the peripheral circadian clocks.Small molecule modifiers of circadian clocks.Global loss of bmal1 expression alters adipose tissue hormones, gene expression and glucose metabolismPD-L1-driven tolerance protects neurogenin3-induced islet neogenesis to reverse established type 1 diabetes in NOD mice.Trastuzumab alters the expression of genes essential for cardiac function and induces ultrastructural changes of cardiomyocytes in mice.The Fragile X proteins Fmrp and Fxr2p cooperate to regulate glucose metabolism in mice.Transcriptional control of circadian metabolic rhythms in the liver.Reprogramming of the circadian clock by nutritional challenge.CLOCK gene variation is associated with incidence of type-2 diabetes and cardiovascular diseases in type-2 diabetic subjects: dietary modulation in the PREDIMED randomized trial.Circadian control of β-cell function and stress responses.Bmal1 and β-cell clock are required for adaptation to circadian disruption, and their loss of function leads to oxidative stress-induced β-cell failure in miceMolecular clock integration of brown adipose tissue formation and function.Consequences of exposure to light at night on the pancreatic islet circadian clock and function in rats.Synchronized human skeletal myotubes of lean, obese and type 2 diabetic patients maintain circadian oscillation of clock genes.Decompensation of β-cells in diabetes: when pancreatic β-cells are on ICE(R).Clocks and cardiovascular function.Experimental and clinical aspects of melatonin and clock genes in diabetes.MicroRNAs modulate core-clock gene expression in pancreatic islets during early postnatal life in rats.Pancreatic α- and β-cellular clocks have distinct molecular properties and impact on islet hormone secretion and gene expression.Unique Aspects of Cryptochrome in Chronobiology and Metabolism, Pancreatic β-Cell Dysfunction, and Regeneration: Research into Cysteine414-Alanine Mutant CRY1.Circadian factors BMAL1 and RORα control HIF-1α transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc healthA functional circadian clock is required for proper insulin secretion by human pancreatic islet cells.Suppression of circadian secretion of glucagon-like peptide-1 by the saturated fatty acid, palmitate.Circadian rhythms in mitochondrial respiration.Decreased insulin secretion in pregnant rats fed a low protein diet.A role for circadian clock in metabolic disease.Untimely Oxidative Stress in β-cells Leads to Diabetes - Role of Circadian Clock in β-cell Function.Circadian Rhythms in Diet-Induced Obesity.
P2860
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P2860
Loss of Bmal1 leads to uncoupling and impaired glucose-stimulated insulin secretion in β-cells.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Loss of Bmal1 leads to uncoupl ...... insulin secretion in β-cells.
@ast
Loss of Bmal1 leads to uncoupl ...... insulin secretion in β-cells.
@en
type
label
Loss of Bmal1 leads to uncoupl ...... insulin secretion in β-cells.
@ast
Loss of Bmal1 leads to uncoupl ...... insulin secretion in β-cells.
@en
prefLabel
Loss of Bmal1 leads to uncoupl ...... insulin secretion in β-cells.
@ast
Loss of Bmal1 leads to uncoupl ...... insulin secretion in β-cells.
@en
P2093
P2860
P356
P1433
P1476
Loss of Bmal1 leads to uncoupl ...... insulin secretion in β-cells.
@en
P2093
David D Moore
Jeongkyung Lee
Mi-Sun Kim
Rongying Li
Victoria Y Liu
Vijay K Yechoor
P2860
P304
P356
10.4161/ISL.3.6.18157
P577
2011-11-01T00:00:00Z