Convergent Evolution of Calcineurin Pathway Roles in Thermotolerance and Virulence in Candida glabrata. - Wikidata - thesis-toulmin - TriplyDB

Convergent Evolution of Calcineurin Pathway Roles in Thermotolerance and Virulence in Candida glabrata.

Convergent Evolution of Calcineurin Pathway Roles in Thermotolerance and Virulence in Candida glabrata.

http://www.wikidata.org/entity/Q35994977

about

Calcineurin-Crz1 signaling in lower eukaryotes Calcineurin plays key roles in the dimorphic transition and virulence of the human pathogenic zygomycete Mucor circinelloides Calcineurin is required for pseudohyphal growth, virulence, and drug resistance in Candida lusitaniae Posaconazole exhibits in vitro and in vivo synergistic antifungal activity with caspofungin or FK506 against Candida albicans Systematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genes Species in the Cryptococcus gattii Complex Differ in Capsule and Cell Size following Growth under Capsule-Inducing Conditions Calcineurin governs thermotolerance and virulence of Cryptococcus gattii.Generational distribution of a Candida glabrata population: Resilient old cells prevail, while younger cells dominate in the vulnerable host Calcineurin controls hyphal growth, virulence, and drug tolerance of Candida tropicalis.Calcineurin as a Multifunctional Regulator: Unraveling Novel Functions in Fungal Stress Responses, Hyphal Growth, Drug Resistance, and Pathogenesis Dissection of Ire1 functions reveals stress response mechanisms uniquely evolved in Candida glabrata.Of mice, flies--and men? Comparing fungal infection models for large-scale screening efforts.KRE5 Suppression Induces Cell Wall Stress and Alternative ER Stress Response Required for Maintaining Cell Wall Integrity in Candida glabrata Anticandidal Effect and Mechanisms of Monoterpenoid, Perillyl Alcohol against Candida albicans Elucidation of the calcineurin-Crz1 stress response transcriptional network in the human fungal pathogen Cryptococcus neoformans Milbemycins: more than efflux inhibitors for fungal pathogens Inhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction.Upregulation of the Adhesin Gene EPA1 Mediated by PDR1 in Candida glabrata Leads to Enhanced Host Colonization.Conserved and Diverged Functions of the Calcineurin-Activated Prz1 Transcription Factor in Fission Yeast.Crz1p regulates pH homeostasis in Candida glabrata by altering membrane lipid composition.A cytoplasmic new catalytic subunit of calcineurin in Trypanosoma cruzi and its molecular and functional characterization Hsp90-dependent regulatory circuitry controlling temperature-dependent fungal development and virulence.Calcineurin signaling: lessons from Candida species.Evolution of regulatory networks in Candida glabrata: learning to live with the human host.Calcineurin orchestrates dimorphic transitions, antifungal drug responses and host-pathogen interactions of the pathogenic mucoralean fungus Mucor circinelloides.Insights into the mode of action of anticandidal herbal monoterpenoid geraniol reveal disruption of multiple MDR mechanisms and virulence attributes in Candida albicans.Sesamol: a natural phenolic compound with promising anticandidal potential.Lactate signalling regulates fungal β-glucan masking and immune evasion.GPI (glycosylphosphatidylinositol)-linked aspartyl proteases regulate vacuole homoeostasis in Candida glabrata.Dissecting the Roles of the Calcineurin Pathway in Unisexual Reproduction, Stress Responses, and Virulence in Cryptococcus deneoformans.Deletion of ADA2 increases antifungal drug susceptibility and virulence in Candida glabrata.Conservation and Divergence in the Candida Species Biofilm Matrix Mannan-Glucan Complex Structure, Function, and Genetic Control.The Unfolded Protein Response Pathway in the Yeast . A Comparative View among Yeast Species

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Convergent Evolution of Calcineurin Pathway Roles in Thermotolerance and Virulence in Candida glabrata.

http://www.wikidata.org/entity/Q35994977

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2012 nî lūn-bûn

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Convergent Evolution of Calcin ...... Virulence in Candida glabrata.

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Convergent Evolution of Calcin ...... Virulence in Candida glabrata.

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Convergent Evolution of Calcin ...... Virulence in Candida glabrata.

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Convergent Evolution of Calcin ...... Virulence in Candida glabrata.

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Convergent Evolution of Calcin ...... Virulence in Candida glabrata.

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Alice Alma C Bungay

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Dawn A Thompson

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Deborah J Springer

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Fitz Gerald S Silao

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Jay H Konieczka

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Jing Zhang

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Marilou G Nicolas

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Soman N Abraham

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Ursela G Bigol

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P2860

Genome evolution in yeasts

Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1

Unique evolution of the UPR pathway with a novel bZIP transcription factor, Hxl1, for controlling pathogenicity of Cryptococcus neoformans

Yeast has homologs (CNA1 and CNA2 gene products) of mammalian calcineurin, a calmodulin-regulated phosphoprotein phosphatase

Calcineurin-dependent growth control in Saccharomyces cerevisiae mutants lacking PMC1, a homolog of plasma membrane Ca2+ ATPases

A conserved family of calcineurin regulators.

Calcineurin inhibits VCX1-dependent H+/Ca2+ exchange and induces Ca2+ ATPases in Saccharomyces cerevisiae.

The unfolded protein response is induced by the cell wall integrity mitogen-activated protein kinase signaling cascade and is required for cell wall integrity in Saccharomyces cerevisiae.

DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways

A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling

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675-691

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scholarly article

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10.1534/G3.112.002279

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6

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2

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Samantha E Bowen

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2012-06-01T00:00:00Z

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225294173

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22690377

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Candida glabrata

convergent evolution

heat acclimation

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3362297

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