The master negative regulator REST/NRSF controls adult neurogenesis by restraining the neurogenic program in quiescent stem cells.
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Insights into the Biology and Therapeutic Applications of Neural Stem CellsThe Transcription Repressor REST in Adult Neurons: Physiology, Pathology, and Diseases(1,2,3)Molecular Biomarkers for Embryonic and Adult Neural Stem Cell and NeurogenesisThe role of targeted protein degradation in early neural developmentLong non-coding RNA-dependent transcriptional regulation in neuronal development and diseaseChronic Social Stress Affects Synaptic Maturation of Newly Generated Neurons in the Adult Mouse Dentate GyrusDual and Opposing Roles of MicroRNA-124 in Epilepsy Are Mediated through Inflammatory and NRSF-Dependent Gene Networks.A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tractComparison of REST cistromes across human cell types reveals common and context-specific functionsThe transcription factor NRSF contributes to epileptogenesis by selective repression of a subset of target genes.p120-catenin regulates REST and CoREST, and modulates mouse embryonic stem cell differentiationC-terminal domain small phosphatase 1 and MAP kinase reciprocally control REST stability and neuronal differentiation.REST controls self-renewal and tumorigenic competence of human glioblastoma cells.Elevated IKKα accelerates the differentiation of human neuronal progenitor cells and induces MeCP2-dependent BDNF expression.Transcriptome analysis of a rotenone model of parkinsonism reveals complex I-tied and -untied toxicity mechanisms common to neurodegenerative diseases.MicroRNA-9 controls dendritic development by targeting REST.Neurogenesis in the embryonic and adult brain: same regulators, different rolesAn RNA binding protein promotes axonal integrity in peripheral neurons by destabilizing REST.Nontelomeric splice variant of telomere repeat-binding factor 2 maintains neuronal traits by sequestering repressor element 1-silencing transcription factor.Repressor element 1 silencing transcription factor (REST) controls radial migration and temporal neuronal specification during neocortical development.Protective variant for hippocampal atrophy identified by whole exome sequencing.Convergence of normal stem cell and cancer stem cell developmental stage: Implication for differential therapiesSOX2 primes the epigenetic landscape in neural precursors enabling proper gene activation during hippocampal neurogenesis.Identification of REST targets in the Xenopus tropicalis genomeRE1 silencing transcription factor (REST) negatively regulates ALL1-fused from chromosome 1q (AF1q) gene transcription.Transcriptional Mechanisms of Proneural Factors and REST in Regulating Neuronal Reprogramming of Astrocytes.Profiling of REST-Dependent microRNAs Reveals Dynamic Modes of Expression.Orchestrating transcriptional control of adult neurogenesis.Transcriptional control of glutamatergic differentiation during adult neurogenesisDirecting neuronal differentiation of primary neural progenitor cells by gene knockdown approach.REST regulates the pool size of the different neural lineages by restricting the generation of neurons and oligodendrocytes from neural stem/progenitor cells.The deubiquitylase USP37 links REST to the control of p27 stability and cell proliferationZebrafish rest regulates developmental gene expression but not neurogenesisREST Regulates Non-Cell-Autonomous Neuronal Differentiation and Maturation of Neural Progenitor Cells via Secretogranin II.REST-miR-21-SOX2 axis maintains pluripotency in E14Tg2a.4 embryonic stem cellsTrans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse modelsVascular endothelial growth factor receptor 3 controls neural stem cell activation in mice and humansChromatin Remodeling Factor Brg1 Supports the Early Maintenance and Late Responsiveness of Nestin-Lineage Adult Neural Stem and Progenitor Cells.Neuron-restrictive silencer factor (NRSF) represses cocaine- and amphetamine-regulated transcript (CART) transcription and antagonizes cAMP-response element-binding protein signaling through a dual NRSE mechanismEpigenetics and epilepsy.
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P2860
The master negative regulator REST/NRSF controls adult neurogenesis by restraining the neurogenic program in quiescent stem cells.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The master negative regulator ...... ogram in quiescent stem cells.
@ast
The master negative regulator ...... ogram in quiescent stem cells.
@en
type
label
The master negative regulator ...... ogram in quiescent stem cells.
@ast
The master negative regulator ...... ogram in quiescent stem cells.
@en
prefLabel
The master negative regulator ...... ogram in quiescent stem cells.
@ast
The master negative regulator ...... ogram in quiescent stem cells.
@en
P2093
P2860
P1476
The master negative regulator ...... ogram in quiescent stem cells.
@en
P2093
Jenny Hsieh
Kerstin Ure
Laura Yuan
Mostafa Nashaat
Peiguo Ding
Robert E Hammer
Zhengliang Gao
P2860
P304
P356
10.1523/JNEUROSCI.1604-11.2011
P407
P577
2011-06-01T00:00:00Z