about
Inflammation and intracellular metabolism: new targets in OAPathophysiology of osteoarthritis: canonical NF-κB/IKKβ-dependent and kinase-independent effects of IKKα in cartilage degradation and chondrocyte differentiationTargets, models and challenges in osteoarthritis researchEmergence of scaffold-free approaches for tissue engineering musculoskeletal cartilagesCartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related OsteoarthritismTOR: a potential therapeutic target in osteoarthritis?Boning up on autophagy: the role of autophagy in skeletal biologyIncreased DNA Methylation and Reduced Expression of Transcription Factors in Human Osteoarthritis Cartilage.Corticosterone suppresses IL-1β-induced mPGE2 expression through regulation of the 11β-HSD1 bioactivity of synovial fibroblasts in vitroArticular chondrocyte network mediated by gap junctions: role in metabolic cartilage homeostasis.ADAMTS-7 forms a positive feedback loop with TNF-α in the pathogenesis of osteoarthritis.The relationship of autophagy defects to cartilage damage during joint aging in a mouse model.FoxO transcription factors support oxidative stress resistance in human chondrocytesPeroxisome proliferator-activated receptor γ coactivator 1α and FoxO3A mediate chondroprotection by AMP-activated protein kinase.Chondrocyte clusters adjacent to sites of cartilage degeneration have characteristics of progenitor cells.Mechanical overloading causes mitochondrial superoxide and SOD2 imbalance in chondrocytes resulting in cartilage degeneration.Transthyretin deposition in articular cartilage: a novel mechanism in the pathogenesis of osteoarthritis.Biodynamic performance of hyaluronic acid versus synovial fluid of the knee in osteoarthritis.An Ongoing Assessment of Osteoarthritis in African Americans and Caucasians in North Carolina: The Johnston County Osteoarthritis Project.Elevated expression of periostin in human osteoarthritic cartilage and its potential role in matrix degradation via matrix metalloproteinase-13.The genetic pleiotropy of musculoskeletal aging.Histopathological analyses of murine menisci: implications for joint aging and osteoarthritisOxidative Stress Promotes Peroxiredoxin Hyperoxidation and Attenuates Pro-survival Signaling in Aging Chondrocytes.Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.Cysteine-Mediated Redox Regulation of Cell Signaling in Chondrocytes Stimulated With Fibronectin Fragments.Progranulin knockout accelerates intervertebral disc degeneration in aging miceAgeing and the pathogenesis of osteoarthritis.Relationship of age and body mass index to the expression of obesity and osteoarthritis-related genes in human meniscusAge-related carbonylation of fibrocartilage structural proteins drives tissue degenerative modification.Glucosamine activates autophagy in vitro and in vivo.Specific premature epigenetic aging of cartilage in osteoarthritis.Enhanced expression of the central survival of motor neuron (SMN) protein during the pathogenesis of osteoarthritis.Linked decreases in liver kinase B1 and AMP-activated protein kinase activity modulate matrix catabolic responses to biomechanical injury in chondrocytes.Advances and challenges in gene-based approaches for osteoarthritis.Possible role of methylglyoxal and glyoxalase in arthritis.Ageing and osteoarthritis: a circadian rhythm connection.Use of tissue engineering strategies to repair joint tissues in osteoarthritis: viral gene transfer approaches.DNA Methylation in Osteoarthritis.The role of metabolism in the pathogenesis of osteoarthritis.A new strategy to tackle severe knee osteoarthritis: Combination of intra-articular and intraosseous injections of Platelet Rich Plasma.
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Effects of aging on articular cartilage homeostasis.
@ast
Effects of aging on articular cartilage homeostasis.
@en
type
label
Effects of aging on articular cartilage homeostasis.
@ast
Effects of aging on articular cartilage homeostasis.
@en
prefLabel
Effects of aging on articular cartilage homeostasis.
@ast
Effects of aging on articular cartilage homeostasis.
@en
P2860
P1433
P1476
Effects of aging on articular cartilage homeostasis.
@en
P2093
Martin Lotz
Richard F Loeser
P2860
P304
P356
10.1016/J.BONE.2012.03.023
P577
2012-03-28T00:00:00Z