Co-administration of morphine and oxycodone vaccines reduces the distribution of 6-monoacetylmorphine and oxycodone to brain in rats.
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Pharmacokinetic correlates of the effects of a heroin vaccine on heroin self-administration in ratsNovel pharmacotherapeutic strategies for treatment of opioid-induced neonatal abstinence syndrome.Synthesis and immunological effects of heroin vaccinesCharacterization and optimization of heroin hapten-BSA conjugates: method development for the synthesis of reproducible hapten-based vaccines.The frequency of naive and early-activated hapten-specific B cell subsets dictates the efficacy of a therapeutic vaccine against prescription opioid abuseEffects of an oxycodone conjugate vaccine on oxycodone self-administration and oxycodone-induced brain gene expression in rats.Adjuvants for vaccines to drugs of abuse and addiction.Efficacy, but not antibody titer or affinity, of a heroin hapten conjugate vaccine correlates with increasing hapten densities on tetanus toxoid, but not on CRM197 carriersSelective effects of a morphine conjugate vaccine on heroin and metabolite distribution and heroin-induced behaviors in ratsDynamic vaccine blocks relapse to compulsive intake of heroin.Levels of heroin and its metabolites in blood and brain extracellular fluid after i.v. heroin administration to freely moving rats.Vaccination protects rats from methamphetamine-induced impairment of behavioral responding for food.Injection route and TLR9 agonist addition significantly impact heroin vaccine efficacyConjugate Vaccine Immunotherapy for Substance Use Disorder.Hapten-specific naïve B cells are biomarkers of vaccine efficacy against drugs of abuse.Increased efficacy of a trivalent nicotine vaccine compared to a dose-matched monovalent vaccine when formulated with alumBiologics to treat substance use disorders: Current status and new directionsReduced antinociception of opioids in rats and mice by vaccination with immunogens containing oxycodone and hydrocodone haptens.Current status and future prospects for the development of substance abuse vaccines.A Stable Heroin Analogue That Can Serve as a Vaccine Hapten to Induce Antibodies That Block the Effects of Heroin and Its Metabolites in Rodents and That Cross-React Immunologically with Related Drugs of Abuse.Safety and efficacy of an oxycodone vaccine: Addressing some of the unique considerations posed by opioid abuse.Pharmacological Effects of a Monoclonal Antibody against 6-Monoacetylmorphine upon Heroin-Induced Locomotor Activity and Pharmacokinetics in Mice.Blocking interleukin-4 enhances efficacy of vaccines for treatment of opioid abuse and prevention of opioid overdose.Efficacious Vaccine against Heroin Contaminated with Fentanyl.Improved Admixture Vaccine of Fentanyl and Heroin Hapten Immunoconjugates: Antinociceptive Evaluation of Fentanyl-Contaminated Heroin
P2860
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P2860
Co-administration of morphine and oxycodone vaccines reduces the distribution of 6-monoacetylmorphine and oxycodone to brain in rats.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
@zh-hant
name
Co-administration of morphine ...... nd oxycodone to brain in rats.
@ast
Co-administration of morphine ...... nd oxycodone to brain in rats.
@en
type
label
Co-administration of morphine ...... nd oxycodone to brain in rats.
@ast
Co-administration of morphine ...... nd oxycodone to brain in rats.
@en
prefLabel
Co-administration of morphine ...... nd oxycodone to brain in rats.
@ast
Co-administration of morphine ...... nd oxycodone to brain in rats.
@en
P2093
P2860
P1433
P1476
Co-administration of morphine ...... nd oxycodone to brain in rats.
@en
P2093
A K Birnbaum
A M Tucker
M D Raleigh
M Le Naour
M Pravetoni
P R Pentel
P S Portoghese
T M Harmon
P2860
P304
P356
10.1016/J.VACCINE.2012.04.101
P407
P577
2012-05-11T00:00:00Z