Mutations in the Yeast Hsp70, Ssa1, at P417 Alter ATP Cycling, Interdomain Coupling, and Specific Chaperone Functions.
about
A mitochondrial HSP70 (HSPA9B) is linked to miltefosine resistance and stress response in Leishmania donovani.Endoplasmic reticulum-associated degradation of the renal potassium channel, ROMK, leads to type II Bartter syndrome.Transmembrane helix hydrophobicity is an energetic barrier during the retrotranslocation of integral membrane ERAD substratesDisrupted hydrogen bond network and impaired ATPase activity in an Hsc70 cysteine mutant.The β6/β7 region of the Hsp70 substrate-binding domain mediates heat-shock response and prion propagation.The absence of specific yeast heat-shock proteins leads to abnormal aggregation and compromised autophagic clearance of mutant Huntingtin proteins.
P2860
Mutations in the Yeast Hsp70, Ssa1, at P417 Alter ATP Cycling, Interdomain Coupling, and Specific Chaperone Functions.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Mutations in the Yeast Hsp70, ...... Specific Chaperone Functions.
@ast
Mutations in the Yeast Hsp70, ...... Specific Chaperone Functions.
@en
type
label
Mutations in the Yeast Hsp70, ...... Specific Chaperone Functions.
@ast
Mutations in the Yeast Hsp70, ...... Specific Chaperone Functions.
@en
prefLabel
Mutations in the Yeast Hsp70, ...... Specific Chaperone Functions.
@ast
Mutations in the Yeast Hsp70, ...... Specific Chaperone Functions.
@en
P2093
P2860
P1476
Mutations in the Yeast Hsp70, ...... Specific Chaperone Functions.
@en
P2093
Hardik J Patel
Jeffrey L Brodsky
Patrick G Needham
Patrick H Thibodeau
P2860
P304
P356
10.1016/J.JMB.2015.04.010
P407
P577
2015-04-23T00:00:00Z