Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer's disease.
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Excess cerebral TNF causing glutamate excitotoxicity rationalizes treatment of neurodegenerative diseases and neurogenic pain by anti-TNF agentsCharacterization of Novel Src Family Kinase Inhibitors to Attenuate MicrogliosisNetwork Topology Analysis of Post-Mortem Brain Microarrays Identifies More Alzheimer's Related Genes and MicroRNAs and Points to Novel Routes for Fighting with the DiseasePharmacological targeting of the PDGF-CC signaling pathway for blood-brain barrier restoration in neurological disordersA novel Aβ-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer's disease miceLigand-dependent activation of EphA4 signaling regulates the proteolysis of amyloid precursor protein through a Lyn-mediated pathway.Activation of neurotensin receptor 1 facilitates neuronal excitability and spatial learning and memory in the entorhinal cortex: beneficial actions in an Alzheimer's disease modelDegenerative alterations in noradrenergic neurons of the locus coeruleus in Alzheimer's diseaseAttenuation of microglial activation in a mouse model of Alzheimer's disease via NFAT inhibitionDrugGenEx-Net: a novel computational platform for systems pharmacology and gene expression-based drug repurposing.APP Regulates Microglial Phenotype in a Mouse Model of Alzheimer's Disease.Oxidation of KCNB1 Potassium Channels Causes Neurotoxicity and Cognitive Impairment in a Mouse Model of Traumatic Brain Injury.Fyn kinase inhibition as a novel therapy for Alzheimer's disease.Masitinib for the treatment of mild to moderate Alzheimer's disease.Tyrosine Kinase Inhibitor as a new Therapy for Ischemic Stroke and other Neurologic Diseases: is there any Hope for a Better Outcome?Targeting Fyn Kinase in Alzheimer's Disease.The Antioxidant Effects of Thymoquinone in Activated BV-2 Murine Microglial Cells.Pomegranate polyphenols and extract inhibit nuclear factor of activated T-cell activity and microglial activation in vitro and in a transgenic mouse model of Alzheimer diseaseRepurposing cancer drugs to treat neurological diseases - Src inhibitors as examples.Tyrosine kinase inhibition increases functional parkin-Beclin-1 interaction and enhances amyloid clearance and cognitive performance.Manganese exposure exacerbates progressive motor deficits and neurodegeneration in the MitoPark mouse model of Parkinson's disease: Relevance to gene and environment interactions in metal neurotoxicity.The clinically approved drugs dasatinib and bosutinib induce anti-inflammatory macrophages by inhibiting the salt-inducible kinases.NFATc2 Modulates Microglial Activation in the AβPP/PS1 Mouse Model of Alzheimer's Disease.Comparison of anti-inflammatory potential of four different dibenzocyclooctadiene lignans in microglia; action via activation of PKA and Nrf-2 signaling and inhibition of MAPK/STAT/NF-κB pathways.A c-Src Inhibitor Peptide Based on Connexin43 Exerts Neuroprotective Effects through the Inhibition of Glial Hemichannel Activity.Involvement of c-Abl Kinase in Microglial Activation of NLRP3 Inflammasome and Impairment in Autolysosomal System.Oral sensitization to whey proteins induces age- and sex-dependent behavioral abnormality and neuroinflammatory responses in a mouse model of food allergy: a potential role of mast cells.Oxidation of KCNB1 channels in the human brain and in mouse model of Alzheimer's disease
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P2860
Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer's disease.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Inhibition of Src kinase activ ...... model of Alzheimer's disease.
@ast
Inhibition of Src kinase activ ...... model of Alzheimer's disease.
@en
type
label
Inhibition of Src kinase activ ...... model of Alzheimer's disease.
@ast
Inhibition of Src kinase activ ...... model of Alzheimer's disease.
@en
prefLabel
Inhibition of Src kinase activ ...... model of Alzheimer's disease.
@ast
Inhibition of Src kinase activ ...... model of Alzheimer's disease.
@en
P2860
P356
P1476
Inhibition of Src kinase activ ...... model of Alzheimer's disease.
@en
P2093
Colin K Combs
Gunjan Dhawan
P2860
P2888
P356
10.1186/1742-2094-9-117
P577
2012-07-02T00:00:00Z
P5875
P6179
1043809763