Asymmetry and aging of mycobacterial cells lead to variable growth and antibiotic susceptibility - Wikidata - thesis-toulmin - TriplyDB

Asymmetry and aging of mycobacterial cells lead to variable growth and antibiotic susceptibility

Asymmetry and aging of mycobacterial cells lead to variable growth and antibiotic susceptibility

http://www.wikidata.org/entity/Q36096651

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Mycobacterium tuberculosis: success through dormancy Biological consequences and advantages of asymmetric bacterial growth Stochastic expression of a multiple antibiotic resistance activator confers transient resistance in single cells Memory and fitness optimization of bacteria under fluctuating environments Chromosome segregation impacts on cell growth and division site selection in Corynebacterium glutamicum Phosphorylation of the Peptidoglycan Synthase PonA1 Governs the Rate of Polar Elongation in Mycobacteria Cell division site placement and asymmetric growth in mycobacteria Exploitation of Mycobacterium tuberculosis reporter strains to probe the impact of vaccination at sites of infection Mycobacterium tuberculosis proteins involved in mycolic acid synthesis and transport localize dynamically to the old growing pole and septum RipD (Rv1566c) from Mycobacterium tuberculosis: adaptation of an NlpC/p60 domain to a non-catalytic peptidoglycan-binding function New insights into TB physiology suggest untapped therapeutic opportunities Mycobacterium tuberculosis CwsA interacts with CrgA and Wag31, and the CrgA-CwsA complex is involved in peptidoglycan synthesis and cell shape determination Structome analysis of virulent Mycobacterium tuberculosis, which survives with only 700 ribosomes per 0.1 fl of cytoplasm Confinement-Induced Drug-Tolerance in Mycobacteria Mediated by an Efflux Mechanism High Persister Mutants in Mycobacterium tuberculosis Tackling Drug Resistant Infection Outbreaks of Global Pandemic Escherichia coli ST131 Using Evolutionary and Epidemiological Genomics.Metabolic Perspectives on Persistence Micro total analysis systems: fundamental advances and applications in the laboratory, clinic, and field.BactImAS: a platform for processing and analysis of bacterial time-lapse microscopy movies.Mycobacterial gene cuvA is required for optimal nutrient utilization and virulence Multifork chromosome replication in slow-growing bacteria.Mycobacterial Cultures Contain Cell Size and Density Specific Sub-populations of Cells with Significant Differential Susceptibility to Antibiotics, Oxidative and Nitrite Stress An Amidase_3 domain-containing N-acetylmuramyl-L-alanine amidase is required for mycobacterial cell division.Subpolar addition of new cell wall is directed by DivIVA in mycobacteria.Noncanonical SMC protein in Mycobacterium smegmatis restricts maintenance of Mycobacterium fortuitum plasmids.Linking the transcriptional profiles and the physiological states of Mycobacterium tuberculosis during an extended intracellular infection Basal p21 controls population heterogeneity in cycling and quiescent cell cycle states.Repair rather than segregation of damage is the optimal unicellular aging strategy Developmental biology of Streptomyces from the perspective of 100 actinobacterial genome sequences.Identification of novel inhibitors of nonreplicating Mycobacterium tuberculosis using a carbon starvation model Essential gene disruptions reveal complex relationships between phenotypic robustness, pleiotropy, and fitness.Choreography of the Mycobacterium replication machinery during the cell cycle Small but Mighty: Cell Size and Bacteria.Continuous Flow Microfluidic Bioparticle Concentrator.Sources of Variability in a Synthetic Gene Oscillator.Periplasmic Acid Stress Increases Cell Division Asymmetry (Polar Aging) of Escherichia coli.Targeting drug tolerance in mycobacteria: a perspective from mycobacterial biofilms Microfluidic Screening of Electric Fields for Electroporation.Staying in Shape: the Impact of Cell Shape on Bacterial Survival in Diverse Environments The heterogeneous evolution of multidrug-resistant Mycobacterium tuberculosis.

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Asymmetry and aging of mycobacterial cells lead to variable growth and antibiotic susceptibility

http://www.wikidata.org/entity/Q36096651

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2011 nî lūn-bûn

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Asymmetry and aging of mycobac ...... and antibiotic susceptibility

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Asymmetry and aging of mycobac ...... and antibiotic susceptibility

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Asymmetry and aging of mycobac ...... and antibiotic susceptibility

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Bree B Aldridge

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Danielle Heller

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Marta Fernandez-Suarez

http://www.w3.org/2001/XMLSchema#string

Sarah M Fortune

http://www.w3.org/2001/XMLSchema#string

Vijay Ambravaneswaran

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P2860

Aging and death in an organism that reproduces by morphologically symmetric division

Non-genetic heterogeneity from stochastic partitioning at cell division

Wag31, a homologue of the cell division protein DivIVA, regulates growth, morphology and polar cell wall synthesis in mycobacteria

Persister cells, dormancy and infectious disease

Bacterial persistence as a phenotypic switch

SOFT LITHOGRAPHY

Asymmetric segregation of protein aggregates is associated with cellular aging and rejuvenation.

Bet-hedging and epigenetic inheritance in bacterial cell development.

Spatial gradient of protein phosphorylation underlies replicative asymmetry in a bacterium.

Why is long-term therapy required to cure tuberculosis?

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100-104

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10.1126/SCIENCE.1216166

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22174129

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