Viral acute lower respiratory infections impair CD8+ T cells through PD-1
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PD-L1 expression induced by the 2009 pandemic influenza A(H1N1) virus impairs the human T cell responseBalancing Immune Protection and Immune Pathology by CD8(+) T-Cell Responses to Influenza InfectionImmune Response to Human Metapneumovirus Infection: What We Have Learned from the Mouse ModelDendritic cells in human Pneumovirus and Metapneumovirus infectionsThe respiratory microbiome: an underappreciated player in the human response to inhaled pollutants?Control of pathogenic effector T-cell activities in situ by PD-L1 expression on respiratory inflammatory dendritic cells during respiratory syncytial virus infection.Immune responses and hypercoagulation in ERT for Pompe disease are mutation and rhGAA dose dependent.Human metapneumovirus virus-like particles induce protective B and T cell responses in a mouse model.Persistence in Temporary Lung Niches: A Survival Strategy of Lung-Resident Memory CD8+ T Cells.STAT4 deficiency fails to induce lung Th2 or Th17 immunity following primary or secondary respiratory syncytial virus (RSV) challenge but enhances the lung RSV-specific CD8+ T cell immune response to secondary challenge.Acute clearance of human metapneumovirus occurs independently of natural killer cells.Blockade of the programmed death-1 pathway restores sarcoidosis CD4(+) T-cell proliferative capacity.mTOR inhibition improves immune function in the elderly.Lack of PD-L1 expression by iNKT cells improves the course of influenza A infection.Impaired CD8(+) T cell immunity after allogeneic bone marrow transplantation leads to persistent and severe respiratory viral infection.Protective and dysregulated T cell immunity in RSV infectionA broadly neutralizing human monoclonal antibody exhibits in vivo efficacy against both human metapneumovirus and respiratory syncytial virus.Viral infection of human lung macrophages increases PDL1 expression via IFNβ.Beyond adjuvants: immunomodulation strategies to enhance T cell immunityLung CD8+ T Cell Impairment Occurs during Human Metapneumovirus Infection despite Virus-Like Particle Induction of Functional CD8+ T Cells.A Numerically Subdominant CD8 T Cell Response to Matrix Protein of Respiratory Syncytial Virus Controls Infection with Limited Immunopathology.CD8+ cytotoxic T lymphocytes in human influenza virus infectionDysregulation of Antiviral Function of CD8(+) T Cells in the Chronic Obstructive Pulmonary Disease Lung. Role of the PD-1-PD-L1 Axis.Discovering naturally processed antigenic determinants that confer protective T cell immunity.Costimulatory and Coinhibitory Receptor Pathways in Infectious DiseaseB cell-intrinsic and -extrinsic regulation of antibody responses by PARP14, an intracellular (ADP-ribosyl)transferase.Progressive changes in inflammatory and matrix adherence of bronchial epithelial cells with persistent respiratory syncytial virus (RSV) infection (progressive changes in RSV infection).Local blockade of epithelial PDL-1 in the airways enhances T cell function and viral clearance during influenza virus infection.Human metapneumovirus in the preterm neonate: current perspectivesHighly pathological influenza A virus infection is associated with augmented expression of PD-1 by functionally compromised virus-specific CD8+ T cells.PD-L1 limits the mucosal CD8+ T cell response to Chlamydia trachomatis.Effects of corticosteroid plus long-acting beta2-agonist on the expression of PD-L1 in double-stranded RNA-induced lung inflammation in mice.Control of local immunity by airway epithelial cells.Ovarian cancer immunotherapy using PD-L1 siRNA targeted delivery from folic acid-functionalized polyethylenimine: strategies to enhance T cell killing.Modulation of Host Immunity by the Human Metapneumovirus.Aberrant T cell immunity triggered by human Respiratory Syncytial Virus and human Metapneumovirus infection.Multiple Inhibitory Pathways Contribute to Lung CD8+ T Cell Impairment and Protect against Immunopathology during Acute Viral Respiratory InfectionNovel HLA-A2-restricted human metapneumovirus epitopes reduce viral titers in mice and are recognized by human T cells.Differential control of CD4(+) T-cell subsets by the PD-1/PD-L1 axis in a mouse model of allergic asthma.Acute Viral Respiratory Infection Rapidly Induces a CD8+ T Cell Exhaustion-like Phenotype.
P2860
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P2860
Viral acute lower respiratory infections impair CD8+ T cells through PD-1
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Viral acute lower respiratory infections impair CD8+ T cells through PD-1
@ast
Viral acute lower respiratory infections impair CD8+ T cells through PD-1
@en
type
label
Viral acute lower respiratory infections impair CD8+ T cells through PD-1
@ast
Viral acute lower respiratory infections impair CD8+ T cells through PD-1
@en
prefLabel
Viral acute lower respiratory infections impair CD8+ T cells through PD-1
@ast
Viral acute lower respiratory infections impair CD8+ T cells through PD-1
@en
P2093
P2860
P50
P356
P1476
Viral acute lower respiratory infections impair CD8+ T cells through PD-1
@en
P2093
Andrew K Hastings
Annette S Kim
Joyce E Johnson
Kelli L Boyd
Melissa B Downing
Monika Johnson
Sharon J Tollefson
P2860
P304
P356
10.1172/JCI62860
P407
P577
2012-07-17T00:00:00Z