Matrix-dependent perturbation of TGFβ signaling and disease - Wikidata - thesis-toulmin - TriplyDB

Matrix-dependent perturbation of TGFβ signaling and disease

Matrix-dependent perturbation of TGFβ signaling and disease

http://www.wikidata.org/entity/Q36184322

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The pituitary TGFβ1 system as a novel target for the treatment of resistant prolactinomas Medical treatment of aortic aneurysms in Marfan syndrome and other heritable conditions Myofibroblasts: trust your heart and let fate decide.Fibrillin-1 directly regulates osteoclast formation and function by a dual mechanism The Discovery and Early Days of TGF-β: A Historical Perspective Adamtsl2 deletion results in bronchial fibrillin microfibril accumulation and bronchial epithelial dysplasia--a novel mouse model providing insights into geleophysic dysplasia Prestress in the extracellular matrix sensitizes latent TGF-β1 for activation.Pharmacologically Improved Contractility Protects Against Aortic Dissection in Mice With Disrupted Transforming Growth Factor-β Signaling Despite Compromised Extracellular Matrix Properties.Transforming growth factor-beta (TGF- β) signaling in paravertebral muscles in juvenile and adolescent idiopathic scoliosis.Sequestration of latent TGF-β binding protein 1 into CADASIL-related Notch3-ECD deposits Cerebral small vessel disease-related protease HtrA1 processes latent TGF-β binding protein 1 and facilitates TGF-β signaling MicroRNA miR145 regulates TGFBR2 expression and matrix synthesis in vascular smooth muscle cells Tumor suppressor ataxia telangiectasia mutated functions downstream of TGF-β1 in orchestrating profibrotic responses.A potential role for endogenous proteins as sacrificial sunscreens and antioxidants in human tissues.Small leucine-rich proteoglycans exhibit unique spatiotemporal expression profiles during cardiac valve development.Role of mechanotransduction in vascular biology: focus on thoracic aortic aneurysms and dissections.LTBP-2 Has a Single High-Affinity Binding Site for FGF-2 and Blocks FGF-2-Induced Cell Proliferation.Genetic analysis of the contribution of LTBP-3 to thoracic aneurysm in Marfan syndrome.Association between Fibrillin1 Polymorphisms (rs2118181, rs10519177) and Transforming Growth Factor β1 Concentration in Human Plasma.The biology of the extracellular matrix: novel insights.Intricate interplay between astrocytes and motor neurons in ALS.Advancing biomaterials of human origin for tissue engineering.Modifying muscular dystrophy through transforming growth factor-β.The pathology and pathobiology of bicuspid aortic valve: State of the art and novel research perspectives.Identification of candidate downstream targets of TGFβ signaling during palate development by genome-wide transcript profiling.Unchaining the beast; insights from structural and evolutionary studies on TGFβ secretion, sequestration, and activation Smooth muscle cell-specific Tgfbr1 deficiency promotes aortic aneurysm formation by stimulating multiple signaling events.SMAD4 mutations causing Myhre syndrome result in disorganization of extracellular matrix improved by losartan Integrin-modulating therapy prevents fibrosis and autoimmunity in mouse models of scleroderma Distinct signaling pathways activated by "extracellular" and "intracellular" serotonin in heart valve development and disease.Genetic biomarkers in aortopathy.The growth factors involved in flexor tendon repair and adhesion formation.Novel investigational agents for the treatment of scleroderma.Mechanotransduction and fibrosis.We have contact: endothelial cell-smooth muscle cell interactions.Interleukin-1-induced changes in the glioblastoma secretome suggest its role in tumor progression.Mechano-sensitive regulation of gene expression during the embryonic development.The significance of macrophage polarization subtypes for animal models of tissue fibrosis and human fibrotic diseases The N-Terminal Region of Fibrillin-1 Mediates a Bipartite Interaction with LTBP1.Pathophysiological Mechanisms in Sclerosing Skin Diseases.

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P2860

Matrix-dependent perturbation of TGFβ signaling and disease

http://www.wikidata.org/entity/Q36184322

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Matrix-dependent perturbation of TGFβ signaling and disease

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Matrix-dependent perturbation of TGFβ signaling and disease

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Matrix-dependent perturbation of TGFβ signaling and disease

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Matrix-dependent perturbation of TGFβ signaling and disease

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Matrix-dependent perturbation of TGFβ signaling and disease

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Matrix-dependent perturbation of TGFβ signaling and disease

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Elizabeth E Gerber

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Harry C Dietz

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Jefferson J Doyle

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P2860

Mutations in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/aortic dissection and patent ductus arteriosus

Mutations in myosin light chain kinase cause familial aortic dissections

Integrin alphavbeta3, requirement for VEGFR2-mediated activation of SAPK2/p38 and for Hsp90-dependent phosphorylation of focal adhesion kinase in endothelial cells activated by VEGF

Emilin1 links TGF-beta maturation to blood pressure homeostasis

Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein

ADAMTSL2 mutations in geleophysic dysplasia demonstrate a role for ADAMTS-like proteins in TGF-beta bioavailability regulation

ADAMTS10 mutations in autosomal recessive Weill-Marchesani syndrome

Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

A disintegrin-like and metalloprotease (reprolysin-type) with thrombospondin type 1 motif (ADAMTS) superfamily: functions and mechanisms

Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer

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