Mena invasive (Mena(INV)) and Mena11a isoforms play distinct roles in breast cancer cell cohesion and association with TMEM - Wikidata - thesis-toulmin - TriplyDB

Mena invasive (Mena(INV)) and Mena11a isoforms play distinct roles in breast cancer cell cohesion and association with TMEM

Mena invasive (Mena(INV)) and Mena11a isoforms play distinct roles in breast cancer cell cohesion and association with TMEM

http://www.wikidata.org/entity/Q36283722

about

Traversing the basement membrane in vivo: a diversity of strategies Molecular insights on context-specific role of profilin-1 in cell migration Correlated immunohistochemical and cytological assays for the prediction of hematogenous dissemination of breast cancer 3-D individual cell based computational modeling of tumor cell-macrophage paracrine signaling mediated by EGF and CSF-1 gradients.Signatures of breast cancer metastasis at a glance Chemotaxis in cancer The alternatively-included 11a sequence modifies the effects of Mena on actin cytoskeletal organization and cell behavior Phase 1 dose-finding study of rebastinib (DCC-2036) in patients with relapsed chronic myeloid leukemia and acute myeloid leukemia.Blood vessel endothelium-directed tumor cell streaming in breast tumors requires the HGF/C-Met signaling pathway.Tumor microenvironment of metastasis and risk of distant metastasis of breast cancer.Invasive breast carcinoma cells from patients exhibit MenaINV- and macrophage-dependent transendothelial migration.Mena invasive (MenaINV) promotes multicellular streaming motility and transendothelial migration in a mouse model of breast cancer Menacalc, a quantitative method of metastasis assessment, as a prognostic marker for axillary node-negative breast cancer.Translocated in liposarcoma regulates the distribution and function of mammalian enabled, a modulator of actin dynamics.Mena, a new available marker in tumors of salivary glands?PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena.Splicing program of human MENA produces a previously undescribed isoform associated with invasive, mesenchymal-like breast tumors.Mena binds α5 integrin directly and modulates α5β1 function.Selectivity in subunit composition of Ena/VASP tetramers.Characterization of the expression of the pro-metastatic Mena(INV) isoform during breast tumor progression Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy Mena(INV) dysregulates cortactin phosphorylation to promote invadopodium maturation.Macrophage-dependent tumor cell transendothelial migration is mediated by Notch1/MenaINV-initiated invadopodium formation.The pattern of hMENA isoforms is regulated by TGF-β1 in pancreatic cancer and may predict patient outcome.Autocrine HBEGF expression promotes breast cancer intravasation, metastasis and macrophage-independent invasion in vivo.Quantitative assessment of invasive mena isoforms (Menacalc) as an independent prognostic marker in breast cancer.Imaging interactions between macrophages and tumour cells that are involved in metastasis in vivo and in vitro.Directed cell invasion and migration during metastasis.Integrated Analysis of Intracellular Dynamics of MenaINV Cancer Cells in a 3D Matrix.Tumor Cell Invadopodia: Invasive Protrusions that Orchestrate Metastasis.Molecular pathology as the driving force for personalized oncology.Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism.Loss of Kaiso expression in breast cancer cells prevents intra-vascular invasion in the lung and secondary metastasis.A metastasis biomarker (MetaSite Breast™ Score) is associated with distant recurrence in hormone receptor-positive, HER2-negative early-stage breast cancer.Chemotherapy-induced metastasis: mechanisms and translational opportunities.

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P2860

Mena invasive (Mena(INV)) and Mena11a isoforms play distinct roles in breast cancer cell cohesion and association with TMEM

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2011 nî lūn-bûn

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Mena invasive (Mena(INV)) and ...... sion and association with TMEM

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Mena invasive (Mena(INV)) and ...... sion and association with TMEM

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Mena invasive (Mena(INV)) and ...... sion and association with TMEM

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Mena invasive (Mena(INV)) and ...... sion and association with TMEM

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Mena invasive (Mena(INV)) and ...... sion and association with TMEM

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Clinical & Experimental Metastasis

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Mena invasive (Mena(INV)) and ...... sion and association with TMEM

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Brian D Robinson

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Esther Adler

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Evanthia T Roussos

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Frank B Gertler

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Joan G Jones

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John S Condeelis

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Maja H Oktay

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Robert Stobezki

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Sumanta Goswami

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Yarong Wang

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P2860

Simultaneous imaging of GFP, CFP and collagen in tumors in vivo using multiphoton microscopy

Human Mena protein, a serex-defined antigen overexpressed in breast cancer eliciting both humoral and CD8+ T-cell immune response

Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility

Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics

Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy

Nonlinear magic: multiphoton microscopy in the biosciences

Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors

Breast cancer metastasis: markers and models

Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease

Critical roles of phosphorylation and actin binding motifs, but not the central proline-rich region, for Ena/vasodilator-stimulated phosphoprotein (VASP) function during cell migration.

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Michele Balsamo

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