Diverse functional outcomes of Plasmodium falciparum ligation of EPCR: potential implications for malarial pathogenesis. - Wikidata - thesis-toulmin - TriplyDB

Diverse functional outcomes of Plasmodium falciparum ligation of EPCR: potential implications for malarial pathogenesis.

Diverse functional outcomes of Plasmodium falciparum ligation of EPCR: potential implications for malarial pathogenesis.

http://www.wikidata.org/entity/Q36322439

about

The role of EPCR in the pathogenesis of severe malaria Plasmodium falciparum var genes expressed in children with severe malaria encode CIDRα1 domains.Interaction between Endothelial Protein C Receptor and Intercellular Adhesion Molecule 1 to Mediate Binding of Plasmodium falciparum-Infected Erythrocytes to Endothelial Cells.EPCR and Malaria Severity: The Center of a Perfect Storm.The Severity of Plasmodium falciparum Infection Is Associated with Transcript Levels of var Genes Encoding Endothelial Protein C Receptor-Binding P. falciparum Erythrocyte Membrane Protein 1.Cytoadhesion to gC1qR through Plasmodium falciparum Erythrocyte Membrane Protein 1 in Severe Malaria.Severe adult malaria is associated with specific PfEMP1 adhesion types and high parasite biomass.Thrombin Cleavage of Plasmodium falciparum Erythrocyte Membrane Protein 1 Inhibits Cytoadherence.Plasma Ang2 and ADAM17 levels are elevated during clinical malaria; Ang2 level correlates with severity and expression of EPCR-binding PfEMP1.Dynamic interactions of Plasmodium spp. with vascular endothelium.Severe malaria: what's new on the pathogenesis front?Dysregulation of pulmonary endothelial protein C receptor and thrombomodulin in severe falciparum malaria-associated ARDS relevant to hemozoin.Characterisation of Plasmodium falciparum populations selected on the human endothelial receptors P-selectin, E-selectin, CD9 and CD151.In vitro inhibition and reversal of Plasmodium falciparum cytoadherence to endothelium by monoclonal antibodies to ICAM-1 and CD36.Rupture and Release: A Role for Soluble Erythrocyte Content in the Pathology of Cerebral Malaria.Pathogenicity Determinants of the Human Malaria Parasite Plasmodium falciparum Have Ancient Origins.Breaking down brain barrier breaches in cerebral malaria Plasmodium falciparum EPCR-binding PfEMP1 expression increases with malaria disease severity and is elevated in retinopathy negative cerebral malaria.A semi-synthetic glycosaminoglycan analogue inhibits and reverses Plasmodium falciparum cytoadherence.Linking EPCR-Binding PfEMP1 to Brain Swelling in Pediatric Cerebral Malaria.Pathophysiology, clinical presentation, and treatment of coma and acute kidney injury complicating falciparum malaria.Infected erythrocytes expressing DC13 PfEMP1 differ from recombinant proteins in EPCR-binding function.

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Diverse functional outcomes of Plasmodium falciparum ligation of EPCR: potential implications for malarial pathogenesis.

http://www.wikidata.org/entity/Q36322439

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Andrew J Brazier

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Joseph D Smith

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Marion Avril

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Mark R Gillrie

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May Ho

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Monique F Stins

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P2860

Lethal malaria: Marchiafava and Bignami were right

Identification of the protein C/activated protein C binding sites on the endothelial cell protein C receptor. Implications for a novel mode of ligand recognition by a major histocompatibility complex class 1-type receptor

Human protein C receptor is present primarily on endothelium of large blood vessels: implications for the control of the protein C pathway

The cytoprotective protein C pathway

Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes--divide and conquer.

Adhesion of Plasmodium falciparum-infected erythrocytes to human cells: molecular mechanisms and therapeutic implications.

Investigating the host binding signature on the Plasmodium falciparum PfEMP1 protein family.

Zinc modulates the interaction of protein C and activated protein C with endothelial cell protein C receptor

Plasmodium falciparum-infected erythrocytes induce tissue factor expression in endothelial cells and support the assembly of multimolecular coagulation complexes

The systemic pathology of cerebral malaria in African children

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10.1111/CMI.12479

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12

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Plasmodium falciparum

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