The neurofilament middle molecular mass subunit carboxyl-terminal tail domains is essential for the radial growth and cytoskeletal architecture of axons but not for regulating neurofilament transport rate.
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Role of phosphorylation on the structural dynamics and function of types III and IV intermediate filamentsNeurofilaments switch between distinct mobile and stationary states during their transport along axons.Neurofilaments form a highly stable stationary cytoskeleton after reaching a critical level in axons.Myosin Va increases the efficiency of neurofilament transport by decreasing the duration of long-term pauses.Specific calpain inhibition by calpastatin prevents tauopathy and neurodegeneration and restores normal lifespan in tau P301L miceAltered axonal architecture by removal of the heavily phosphorylated neurofilament tail domains strongly slows superoxide dismutase 1 mutant-mediated ALS.The C-terminal domains of NF-H and NF-M subunits maintain axonal neurofilament content by blocking turnover of the stationary neurofilament networkIncrimination of heterogeneous nuclear ribonucleoprotein E1 (hnRNP-E1) as a candidate sensor of physiological folate deficiency.Dissociation of Axonal Neurofilament Content from Its Transport RateNeurofilament Phosphorylation during Development and Disease: Which Came First, the Phosphorylation or the Accumulation?Failure of lower motor neuron radial outgrowth precedes retrograde degeneration in a feline model of spinal muscular atrophy.Neurofilaments at a glance.Neurotrophins and peripheral neuropathies.Methyl-Arginine Profile of Brain from Aged PINK1-KO+A53T-SNCA Mice Suggests Altered Mitochondrial Biogenesis.Cytoskeletal transport in the aging brain: focus on the cholinergic system.Autoimmune-induced preferential depletion of myelin-associated glycoprotein (MAG) is genetically regulated in relapsing EAE (B6 x SJL) F1 miceRegulation of neurofilament dynamics by phosphorylation.RE1 silencing transcription factor is involved in regulating neuron-specific expression of alpha-internexin and neurofilament genes.MSC p43 required for axonal development in motor neurons.Axonal protective effects of the myelin-associated glycoprotein.Phosphorylation of highly conserved neurofilament medium KSP repeats is not required for myelin-dependent radial axonal growthThe interaction of neurofilaments with the microtubule motor cytoplasmic dynein.Neurofilament phosphorylation and their proline-directed kinases in health and disease.Neurofilament dynamics and involvement in neurological disorders.Genetic and clinical characteristics of NEFL-related Charcot-Marie-Tooth disease.Specialized roles of neurofilament proteins in synapses: Relevance to neuropsychiatric disorders.Lessons from Animal Models of Cytoplasmic Intermediate Filament Proteins.Neurofilaments and Neurofilament Proteins in Health and Disease.Psychosine induces the dephosphorylation of neurofilaments by deregulation of PP1 and PP2A phosphatases.The diameter of cortical axons depends both on the area of origin and target.
P2860
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P2860
The neurofilament middle molecular mass subunit carboxyl-terminal tail domains is essential for the radial growth and cytoskeletal architecture of axons but not for regulating neurofilament transport rate.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
The neurofilament middle molec ...... neurofilament transport rate.
@ast
The neurofilament middle molec ...... neurofilament transport rate.
@en
type
label
The neurofilament middle molec ...... neurofilament transport rate.
@ast
The neurofilament middle molec ...... neurofilament transport rate.
@en
prefLabel
The neurofilament middle molec ...... neurofilament transport rate.
@ast
The neurofilament middle molec ...... neurofilament transport rate.
@en
P2093
P2860
P356
P1476
The neurofilament middle molec ...... neurofilament transport rate.
@en
P2093
Aidong Yuan
Asok Kumar
Jabbar Campbell
Mala V Rao
Ralph A Nixon
Takahiro Gotow
Yasuo Uchiyama
P2860
P304
P356
10.1083/JCB.200308076
P407
P577
2003-12-01T00:00:00Z