ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix.
about
Matrix rigidity regulates cancer cell growth and cellular phenotype.Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growthGrowth control by intracellular tension and extracellular stiffnessSubstrate modulus directs neural stem cell behaviorPaxillin comes of ageUse of three-dimensional collagen gels to study mechanotransduction in T47D breast epithelial cellsFocal adhesions, stress fibers and mechanical tensionRho-associated kinase signalling and the cancer microenvironment: novel biological implications and therapeutic opportunitiesEpithelia migration: a spatiotemporal interplay between contraction and adhesionMechanical signaling in reproductive tissues: mechanisms and importanceFrom mechanical force to RhoA activationApproaches to manipulating the dimensionality and physicochemical properties of common cellular scaffoldsEpithelial machines of morphogenesis and their potential application in organ assembly and tissue engineeringWhy the stroma matters in breast cancer: insights into breast cancer patient outcomes through the examination of stromal biomarkersTumor stiffness is unrelated to myosin light chain phosphorylation in cancer cellsComposite alginate gels for tunable cellular microenvironment mechanics.A novel mutation in β integrin reveals an integrin-mediated interaction between the extracellular matrix and cki-1/p27KIP1Growth of human breast tissues from patient cells in 3D hydrogel scaffoldsFrom molecular signal activation to locomotion: an integrated, multiscale analysis of cell motility on defined matricesCancer cell invasion is enhanced by applied mechanical stimulationTargeting TBK1 inhibits migration and resistance to MEK inhibitors in mutant NRAS melanoma.Role of surface chemistry in protein remodeling at the cell-material interfaceForce fluctuations within focal adhesions mediate ECM-rigidity sensing to guide directed cell migration.Environmental particulate (PM2.5) augments stiffness-induced alveolar epithelial cell mechanoactivation of transforming growth factor betaFighting the force: Potential of homeobox genes for tumor microenvironment regulationP190A RhoGAP is required for mammary gland developmentβ-Adrenergic inhibition of contractility in L6 skeletal muscle cellsBi-directional signaling: extracellular matrix and integrin regulation of breast tumor progressionThe extracellular matrix: a dynamic niche in cancer progressionIntegrated micro/nanoengineered functional biomaterials for cell mechanics and mechanobiology: a materials perspective.Tissue stiffness dictates development, homeostasis, and disease progression.Matrix microarchitecture and myosin II determine adhesion in 3D matrices.Focal adhesion kinase as a regulator of cell tension in the progression of cancer.Substrate rigidity regulates the formation and maintenance of tissues.Rho kinase, myosin-II, and p42/44 MAPK control extracellular matrix-mediated apical bile canalicular lumen morphogenesis in HepG2 cells.Collagen reorganization at the tumor-stromal interface facilitates local invasion.Determining the mechanical properties of human corneal basement membranes with atomic force microscopyCollagen fibril flow and tissue translocation coupled to fibroblast migration in 3D collagen matricesSubstrate rigidity regulates Ca2+ oscillation via RhoA pathway in stem cells.A photo-modulatable material for probing cellular responses to substrate rigidity.
P2860
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P2860
ROCK-generated contractility regulates breast epithelial cell differentiation in response to the physical properties of a three-dimensional collagen matrix.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
ROCK-generated contractility r ...... e-dimensional collagen matrix.
@ast
ROCK-generated contractility r ...... e-dimensional collagen matrix.
@en
type
label
ROCK-generated contractility r ...... e-dimensional collagen matrix.
@ast
ROCK-generated contractility r ...... e-dimensional collagen matrix.
@en
prefLabel
ROCK-generated contractility r ...... e-dimensional collagen matrix.
@ast
ROCK-generated contractility r ...... e-dimensional collagen matrix.
@en
P2093
P2860
P356
P1476
ROCK-generated contractility r ...... e-dimensional collagen matrix.
@en
P2093
Channing J Der
Michele A Wozniak
Patricia A Solski
Patricia J Keely
Radhika Desai
P2860
P304
P356
10.1083/JCB.200305010
P407
P577
2003-11-01T00:00:00Z