Quantitative proteomic analysis of Niemann-Pick disease, type C1 cerebellum identifies protein biomarkers and provides pathological insight.
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Genetic dissection of a cell-autonomous neurodegenerative disorder: lessons learned from mouse models of Niemann-Pick disease type CStructural Basis for Ligand Regulation of the Fatty Acid-binding Protein 5, Peroxisome Proliferator-activated Receptor / (FABP5-PPAR / ) Signaling PathwayPre-symptomatic activation of antioxidant responses and alterations in glucose and pyruvate metabolism in Niemann-Pick Type C1-deficient murine brainGpnmb Is a Potential Marker for the Visceral Pathology in Niemann-Pick Type C DiseaseFostering collaborative research for rare genetic disease: the example of niemann-pick type C diseaseAdaptations of energy metabolism associated with increased levels of mitochondrial cholesterol in Niemann-Pick type C1-deficient cells.Analytical Characterization of Methyl-β-Cyclodextrin for Pharmacological Activity to Reduce Lysosomal Cholesterol Accumulation in Niemann-Pick Disease Type C1 Cells.Niemann-Pick C disease and mobilization of lysosomal cholesterol by cyclodextrinCholesterol homeostatic responses provide biomarkers for monitoring treatment for the neurodegenerative disease Niemann-Pick C1 (NPC1)The Proteome Profiles of the Cerebellum of Juvenile, Adult and Aged Rats--An Ontogenetic Study.Quantitative Proteomics of Human Fibroblasts with I1061T Mutation in Niemann-Pick C1 (NPC1) Protein Provides Insights into the Disease Pathogenesis.Immune dysfunction in Niemann-Pick disease type C.Efficacy of N-acetylcysteine in phenotypic suppression of mouse models of Niemann-Pick disease, type C1.Cerebrospinal Fluid Calbindin D Concentration as a Biomarker of Cerebellar Disease Progression in Niemann-Pick Type C1 Disease.Sphingolipid signalling mediates mitochondrial dysfunctions and reduced chronological lifespan in the yeast model of Niemann-Pick type C1.Intrathecal 2-hydroxypropyl-β-cyclodextrin decreases neurological disease progression in Niemann-Pick disease, type C1: a non-randomised, open-label, phase 1-2 trial.NMR analysis reveals significant differences in the plasma metabolic profiles of Niemann Pick C1 patients, heterozygous carriers, and healthy controls.Vitamin E dietary supplementation improves neurological symptoms and decreases c-Abl/p73 activation in Niemann-Pick C miceProteinProcessor: A probabilistic analysis using mass accuracy and the MS spectrumPharmacologic Treatment Assigned for Niemann Pick Type C1 Disease Partly Changes Behavioral Traits in Wild-Type Mice.FTY720/fingolimod increases NPC1 and NPC2 expression and reduces cholesterol and sphingolipid accumulation in Niemann-Pick type C mutant fibroblasts.Miglustat in Niemann-Pick disease type C patients: a review
P2860
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P2860
Quantitative proteomic analysis of Niemann-Pick disease, type C1 cerebellum identifies protein biomarkers and provides pathological insight.
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2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
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2012年學術文章
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2012年學術文章
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name
Quantitative proteomic analysi ...... provides pathological insight.
@ast
Quantitative proteomic analysi ...... provides pathological insight.
@en
type
label
Quantitative proteomic analysi ...... provides pathological insight.
@ast
Quantitative proteomic analysi ...... provides pathological insight.
@en
prefLabel
Quantitative proteomic analysi ...... provides pathological insight.
@ast
Quantitative proteomic analysi ...... provides pathological insight.
@en
P2093
P2860
P1433
P1476
Quantitative proteomic analysi ...... provides pathological insight.
@en
P2093
Alfred L Yergey
Celine V M Cluzeau
Cynthia L Toth
Forbes D Porter
Hyun-sik Jun
Michelle K Dail
Nicole M Yanjanin
Peter S Backlund
Stephan Siebel
Stephanie M Cologna
P2860
P304
P356
10.1371/JOURNAL.PONE.0047845
P407
P577
2012-10-29T00:00:00Z