Dissociation of mitogenesis and late-stage promotion of tumor cell phenotype by phorbol esters: mitogen-resistant variants are sensitive to promotion
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Metallic nickel nanoparticles may exhibit higher carcinogenic potential than fine particles in JB6 cellsCyclin-dependent kinase 3-mediated activating transcription factor 1 phosphorylation enhances cell transformationMolecular and cellular targetsNovel human PDCD4 (H731) gene expressed in proliferative cells is expressed in the small duct epithelial cells of the breast as revealed by an anti-H731 antibodyA novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-kappaB or ODC transactivationMolecular cloning, DNA sequence analysis, and biochemical characterization of a novel 65-kDa FK506-binding protein (FKBP65)Ribosomal S6 kinase 2 is a key regulator in tumor promoter induced cell transformation.Protein phosphorylation in a tetradecanoyl phorbol acetate-nonproliferative variant of 3T3 cells.A Swiss 3T3 variant cell line resistant to the effects of tumor promoters cannot be transformed by srcPhosphorylation of NFAT3 by CDK3 induces cell transformation and promotes tumor growth in skin cancer.Role of NEK6 in tumor promoter-induced transformation in JB6 C141 mouse skin epidermal cells.Kaempferol inhibits UVB-induced COX-2 expression by suppressing Src kinase activityFibroblast and Epidermal Growth Factors Utilize Different Signaling Pathways to Induce Anchorage-independent Cell Transformation in JB6 Cl41 Mouse Skin Epidermal CellsDifferential expression of an 80-kDa protein kinase C substrate in preneoplastic and neoplastic mouse JB6 cells.Sesquiterpene lactones isolated from indigenous Middle Eastern plants inhibit tumor promoter-induced transformation of JB6 cells.Transactivation of Fra-1 and consequent activation of AP-1 occur extracellular signal-regulated kinase dependently.Eriodictyol inhibits RSK2-ATF1 signaling and suppresses EGF-induced neoplastic cell transformationEupafolin suppresses prostate cancer by targeting phosphatidylinositol 3-kinase-mediated Akt signaling.Autophagy and cellular senescence mediated by Sox2 suppress malignancy of cancer cells.6,7,4'-trihydroxyisoflavone inhibits HCT-116 human colon cancer cell proliferation by targeting CDK1 and CDK2.Gene regulation and genetic susceptibility to neoplastic transformation: AP-1 and p80 expression in JB6 cellsA growth-responsive gene (16C8) in normal mouse fibroblasts homologous to a human collagenase inhibitor with erythroid-potentiating activity: evidence for inducible and constitutive transcripts.Shortage of mitogen-activated protein kinase is responsible for resistance to AP-1 transactivation and transformation in mouse JB6 cells.Quercetin-3-methyl ether suppresses proliferation of mouse epidermal JB6 P+ cells by targeting ERKs.Four New Sulfated Polar Steroids from the Far Eastern Starfish Leptasterias ochotensis: Structures and Activities.Quercetin-3-methyl ether inhibits lapatinib-sensitive and -resistant breast cancer cell growth by inducing G(2)/M arrest and apoptosis.Common and distinct mechanisms of different redox-active carcinogens involved in the transformation of mouse JB6P+ cells.Aloe-emodin suppresses prostate cancer by targeting the mTOR complex 2Targeting of Noncanonical Wnt5a Signaling by AP-1 Blocker Dominant-Negative Jun When It Inhibits Skin Carcinogenesis.Progression toward tumor cell phenotype is enhanced by overexpression of a mutant p53 tumor-suppressor gene isolated from nasopharyngeal carcinoma.Phorbol esters and gene expression: the role of rapid changes in K+ transport in the induction of ornithine decarboxylase by 12-O-tetradecanoylphorbol-13-acetate in BALB/c 3T3 cells and a mutant cell line defective in Na+K+Cl- cotransportTumor promoters induce a specific morphological signature in the nuclear matrix-intermediate filament scaffold of Madin-Darby canine kidney (MDCK) cell colonies.Tumor-promoter-resistant cells lack trisialoganglioside responseOmega 3 but not omega 6 fatty acids inhibit AP-1 activity and cell transformation in JB6 cells.Phosphorylation of histone H3 at serine 10 is indispensable for neoplastic cell transformation.Theaflavin-3, 3'-digallate induces epidermal growth factor receptor downregulation.Evaluation of cancer-preventive activity and structure-activity relationships of 3-demethylubiquinone Q2, isolated from the ascidian Aplidium glabrum, and its synthetic analogs.Effects of MAP kinase inhibitors on epidermal growth factor-induced neoplastic transformation of human keratinocytes.RSK2 as a key regulator in human skin cancer.Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion.
P2860
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P2860
Dissociation of mitogenesis and late-stage promotion of tumor cell phenotype by phorbol esters: mitogen-resistant variants are sensitive to promotion
description
1981 nî lūn-bûn
@nan
1981年の論文
@ja
1981年学术文章
@wuu
1981年学术文章
@zh-cn
1981年学术文章
@zh-hans
1981年学术文章
@zh-my
1981年学术文章
@zh-sg
1981年學術文章
@yue
1981年學術文章
@zh
1981年學術文章
@zh-hant
name
Dissociation of mitogenesis an ...... nts are sensitive to promotion
@ast
Dissociation of mitogenesis an ...... nts are sensitive to promotion
@en
type
label
Dissociation of mitogenesis an ...... nts are sensitive to promotion
@ast
Dissociation of mitogenesis an ...... nts are sensitive to promotion
@en
prefLabel
Dissociation of mitogenesis an ...... nts are sensitive to promotion
@ast
Dissociation of mitogenesis an ...... nts are sensitive to promotion
@en
P2093
P2860
P4510
P356
P1476
Dissociation of mitogenesis an ...... nts are sensitive to promotion
@en
P2093
P2860
P304
P356
10.1073/PNAS.78.11.6912
P407
P577
1981-11-01T00:00:00Z