A relatively low level of ribosome depurination by mutant forms of ricin toxin A chain can trigger protein synthesis inhibition, cell signaling and apoptosis in mammalian cells.
about
The A1 Subunit of Shiga Toxin 2 Has Higher Affinity for Ribosomes and Higher Catalytic Activity than the A1 Subunit of Shiga Toxin 1.Targeting ricin to the ribosome.Toxicity of ricin A chain is reduced in mammalian cells by inhibiting its interaction with the ribosome.Arabidopsis Bax Inhibitor-1 inhibits cell death induced by pokeweed antiviral protein in Saccharomyces cerevisiae.Inhibition of protein synthesis leading to unfolded protein response is the major event in abrin-mediated apoptosis.Functional Assays for Measuring the Catalytic Activity of Ribosome Inactivating Proteins.
P2860
A relatively low level of ribosome depurination by mutant forms of ricin toxin A chain can trigger protein synthesis inhibition, cell signaling and apoptosis in mammalian cells.
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2012 nî lūn-bûn
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A relatively low level of ribo ...... apoptosis in mammalian cells.
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A relatively low level of ribo ...... apoptosis in mammalian cells.
@en
type
label
A relatively low level of ribo ...... apoptosis in mammalian cells.
@ast
A relatively low level of ribo ...... apoptosis in mammalian cells.
@en
prefLabel
A relatively low level of ribo ...... apoptosis in mammalian cells.
@ast
A relatively low level of ribo ...... apoptosis in mammalian cells.
@en
P2093
P2860
P1476
A relatively low level of ribo ...... apoptosis in mammalian cells.
@en
P2093
Amanda E Jetzt
Ju-Shun Cheng
Nilgun E Tumer
Wendie S Cohick
Xiao-Ping Li
P2860
P304
P356
10.1016/J.BIOCEL.2012.09.004
P577
2012-09-12T00:00:00Z