A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs.
about
A systematic screen of FDA-approved drugs for inhibitors of biological threat agentsContinued cytoadherence of Plasmodium falciparum infected red blood cells after antimalarial treatment.Huprines as a new family of dual acting trypanocidal-antiplasmodial agentsSynthesis and antimalarial activity of metal complexes of cross-bridged tetraazamacrocyclic ligands.The concept of privileged structures in rational drug design: focus on acridine and quinoline scaffolds in neurodegenerative and protozoan diseases.Orally bioavailable 6-chloro-7-methoxy-4(1H)-quinolones efficacious against multiple stages of Plasmodium.Plasmodium drug targets outside the genetic control of the parasite.In vivo and in vitro antimalarial properties of azithromycin-chloroquine combinations that include the resistance reversal agent amlodipineSontochin as a guide to the development of drugs against chloroquine-resistant malaria.Synthesis and biological evaluation of 1,4-naphthoquinones and quinoline-5,8-diones as antimalarial and schistosomicidal agents.Design, synthesis, and evaluation of 10-N-substituted acridones as novel chemosensitizers in Plasmodium falciparum.Know your enemy: understanding the role of PfCRT in drug resistance could lead to new antimalarial tactics.Respiratory syncytial virus induces indoleamine 2,3-dioxygenase activity: a potential novel role in the development of allergic disease.Synthesis and evaluation of 7-substituted 4-aminoquinoline analogues for antimalarial activity.Synthesis and Evaluation of Chirally Defined Side Chain Variants of 7-Chloro-4-Aminoquinoline To Overcome Drug Resistance in Malaria Chemotherapy.ATP and luciferase assays to determine the rate of drug action in in vitro cultures of Plasmodium falciparum.Design and synthesis of 3-[(7-chloro-1-oxidoquinolin-4-ylamino)alkyl]-1,3-thiazolidin-4-ones as antimalarial agents.Novel antimalarial aminoquinolines: heme binding and effects on normal or Plasmodium falciparum-parasitized human erythrocytes.Amodiaquine resistance in Plasmodium berghei is associated with PbCRT His95Pro mutation, loss of chloroquine, artemisinin and primaquine sensitivity, and high transcript levels of key transporters.Study of the antimalarial activity of 4-aminoquinoline compounds against chloroquine-sensitive and chloroquine-resistant parasite strains
P2860
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P2860
A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs.
@ast
A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs.
@en
type
label
A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs.
@ast
A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs.
@en
prefLabel
A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs.
@ast
A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs.
@en
P2093
P50
P1476
A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs
@en
P2093
B Kevin Park
Egbaleh Asadollaly
J Prince Jeyadevan
Patrick G Bray
Paul M O'Neill
P304
P356
10.2174/156802606776743147
P577
2006-01-01T00:00:00Z