Directly converted patient-specific induced neurons mirror the neuropathology of FUS with disrupted nuclear localization in amyotrophic lateral sclerosis.
about
Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis.Patient fibroblasts-derived induced neurons demonstrate autonomous neuronal defects in adult-onset Krabbe disease.Decoding ALS: from genes to mechanism.Directly converted iNeuron as a screening model for pathogenic variants.Direct Neuronal Reprogramming for Disease Modeling Studies Using Patient-Derived Neurons: What Have We Learned?Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation.Dysregulated molecular pathways in amyotrophic lateral sclerosis-frontotemporal dementia spectrum disorder.A Metadata Analysis of Oxidative Stress Etiology in Preclinical Amyotrophic Lateral Sclerosis: Benefits of Antioxidant Therapy.Representing Diversity in the Dish: Using Patient-Derived in Vitro Models to Recreate the Heterogeneity of Neurological Disease.
P2860
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P2860
Directly converted patient-specific induced neurons mirror the neuropathology of FUS with disrupted nuclear localization in amyotrophic lateral sclerosis.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Directly converted patient-spe ...... amyotrophic lateral sclerosis.
@ast
Directly converted patient-spe ...... amyotrophic lateral sclerosis.
@en
type
label
Directly converted patient-spe ...... amyotrophic lateral sclerosis.
@ast
Directly converted patient-spe ...... amyotrophic lateral sclerosis.
@en
prefLabel
Directly converted patient-spe ...... amyotrophic lateral sclerosis.
@ast
Directly converted patient-spe ...... amyotrophic lateral sclerosis.
@en
P2093
P2860
P1476
Directly converted patient-spe ...... amyotrophic lateral sclerosis.
@en
P2093
Ji Young Choi
Jinhyuk Lee
Min-Young Noh
Minyeop Nahm
Sejin Hwang
Seung Hyun Kim
Seungbok Lee
Su Min Lim
Sung Hoon Kim
Won Jun Choi
P2860
P2888
P356
10.1186/S13024-016-0075-6
P577
2016-01-22T00:00:00Z
P5875
P6179
1002863936