Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I. - Wikidata - thesis-toulmin - TriplyDB

Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I.

Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I.

http://www.wikidata.org/entity/Q36498347

about

RNAs Containing Modified Nucleotides Fail To Trigger RIG-I Conformational Changes for Innate Immune Signaling mRNA capping: biological functions and applications The Zika virus methyltransferase: structure and functions for drug design perspectives Selective RNA targeting and regulated signaling by RIG-I is controlled by coordination of RNA and ATP binding.Applications of Phosphate Modification and Labeling to Study (m)RNA Caps.Resurrecting ancestral structural dynamics of an antiviral immune receptor: adaptive binding pocket reorganization repeatedly shifts RNA preference.Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs.An aromatic-rich loop couples DNA binding and ATP hydrolysis in the PriA DNA helicase.When your cap matters: structural insights into self vs non-self recognition of 5' RNA by immunomodulatory host proteins.Concise Review: Application of In Vitro Transcribed Messenger RNA for Cellular Engineering and Reprogramming: Progress and Challenges.Discriminating self from non-self in nucleic acid sensing.Protect this house: cytosolic sensing of viruses.Host and Viral Modulation of RIG-I-Mediated Antiviral Immunity.Discrimination of cytosolic self and non-self RNA by RIG-I-like receptors.Discrimination of Self and Non-Self Ribonucleic Acids.Structure of the DEAH/RHA ATPase Prp43p bound to RNA implicates a pair of hairpins and motif Va in translocation along RNA.Nucleic acid-based polymers effective against hepatitis B Virus infection in patients don't harbor immunostimulatory properties in primary isolated liver cells.Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.Binding of the Methyl Donor S-Adenosyl-l-Methionine to Middle East Respiratory Syndrome Coronavirus 2'-O-Methyltransferase nsp16 Promotes Recruitment of the Allosteric Activator nsp10.A general method for rapid and cost-efficient large-scale production of 5' capped RNA.Nucleic Acid Polymers with Accelerated Plasma and Tissue Clearance for Chronic Hepatitis B Therapy.Exosomal proteins as potential markers of tumor diagnosis.Systematic editing of synthetic RIG-I ligands to produce effective antiviral and anti-tumor RNA immunotherapies.Combined roles of ATP and small hairpin RNA in the activation of RIG-I revealed by solution-based analysis.Regulation and function of CMTR1-dependent mRNA cap methylation.The structure of the binary methyltransferase-SAH complex from Zika virus reveals a novel conformation for the mechanism of mRNA capping.A minimal RNA ligand for potent RIG-I activation in living mice.2'-O-methylation of the mRNA cap protects RNAs from decapping and degradation by DXO.Eukaryotic RNA 5'-End NAD+ Capping and DeNADding.Energetics of Preferential Binding of Retinoic Acid-Inducible Gene-I to Double-Stranded Viral RNAs with 5' Tri-/Diphosphate over 5' Monophosphate.Unified mechanisms for self-RNA recognition by RIG-I Singleton-Merten syndrome variants The RNA Helicase DDX6 Associates with RIG-I to Augment Induction of Antiviral Signaling

P2860

Q27468676-ACB69946-DA28-4330-A395-BC6137707213 Q27469050-B8005205-7BE9-458D-9D46-2C6CAF74AF56 Q28114691-DDAD3D3B-5817-488C-8D1C-FF47C1159E6B Q33554200-18037FA9-B49B-489A-ACA2-30296123A5B5 Q33578532-2708FA62-6D20-40C4-8FCA-F0B4A0842220 Q36185915-501AB5B1-C19D-478D-9316-21BAE9C1CDF2 Q37295712-F1133D81-5E14-4606-BA1E-2106E69A4601 Q37522958-2232B7AE-0D80-46D1-9136-9C2CDE743E6E Q37568730-5FA3B87D-52FA-48CE-95FF-CCECB14BAC3F Q38850538-8075ECA5-3895-4275-832C-910FE218512F Q38907820-2712B807-AA89-404E-8D0C-918636898BD9 Q39036428-B778E081-CFD9-4C90-AABD-D4728C4C599E Q39092892-0DBCE913-1DF3-42E9-98FA-B95F1AEBF354 Q39243745-DF39B4EB-150A-494F-AFBA-7AB54968A712 Q40213813-C55A32FE-AD0F-4BE1-8922-BBC9B54CBEF8 Q40239505-55D30679-2A0D-473D-B38D-662FCF9DFEEC Q40302798-ECFF58FE-EDFA-4B98-896B-F854FB78B9FE Q40311451-3B112BC8-12D1-4B15-B38E-8AE11CA53B69 Q40403939-325E5EE3-A74C-40E6-BA0F-124F5BAE808E Q40671228-6B0A82CA-F1F6-4804-B021-BA52722D4F02 Q42209643-027A5BAE-C3C4-4C91-932C-CB92E4D1082D Q47159665-F766CEC3-6717-49DD-9DB4-31AB75602CA6 Q47548653-B08F9A70-9128-467C-B0CC-44C2A28A1CA8 Q47551803-9DFBE8EF-8F98-4C68-9D14-931F732FFCEE Q47710506-CB36F394-0445-4302-8EC7-7779EA1E4BA5 Q49215219-2ACFC62C-6A10-4115-918E-4B312A611B37 Q50335102-B2D94C6C-2FF6-4889-AA9B-2C58860037B5 Q52337014-25527223-9040-41B9-A150-A43494A28114 Q52653653-5A22820B-EF5A-45BF-84ED-215AFC3B248C Q55716457-6DA614FA-2B75-4C81-9785-67AA704F6D96 Q56531142-72BA40B6-F2FB-400E-B58C-010FD889D590 Q56999242-4D5B88B4-21F4-4F30-A440-7465CE01275E

P2860

Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I.

http://www.wikidata.org/entity/Q36498347

description

2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年学术文章

@wuu

2016年学术文章

@zh-cn

2016年学术文章

@zh-hans

2016年学术文章

@zh-my

2016年学术文章

@zh-sg

2016年學術文章

@yue

2016年學術文章

@zh

2016年學術文章

@zh-hant

name

Structural basis for m7G recog ...... innate immune receptor RIG-I.

@ast

Structural basis for m7G recog ...... innate immune receptor RIG-I.

@en

type

label

Structural basis for m7G recog ...... innate immune receptor RIG-I.

@ast

Structural basis for m7G recog ...... innate immune receptor RIG-I.

@en

prefLabel

Structural basis for m7G recog ...... innate immune receptor RIG-I.

@ast

Structural basis for m7G recog ...... innate immune receptor RIG-I.

@en

P1433

Q36498347-EBA2805A-AB87-4D4F-BBAE-61BC110AD74E

P1476

Q36498347-7D22F84B-A6FC-420C-B4E6-2A90CE193C72

P2093

Q36498347-30504F96-0CE7-4291-9DEA-5620833D2B7F

Q36498347-3BA13637-C60D-4AE0-8CCF-D5A3DCD90417

Q36498347-6E7EC738-A07D-4260-8DE8-09FBE4BCEF9B

Q36498347-71E5F107-0EFA-4147-B5A7-8213AF7597F9

Q36498347-AD0E89EA-9CF2-4788-BF03-AC55A7507CC6

Q36498347-B6DDE7D4-ED7E-4184-A0B0-B16C137ADB92

Q36498347-C63D72B5-3953-42D2-807B-44895A41BCE0

Q36498347-C6695221-7FD2-4CB8-AF6B-7509956E1318

P2860

Q36498347-05046898-D2C7-4AE6-8684-DA9798D4B7E5

Q36498347-0D6D9894-66C7-4FC5-8A0F-86A1A011C37F

Q36498347-2339A82B-A9B7-46CA-9865-194821320ADD

Q36498347-248F731A-FE74-4D25-8D55-A137E639E53D

Q36498347-38F89E73-E1C8-4503-9727-A05D0E9BB37A

Q36498347-3DF1BD4A-206E-49E6-AAEE-3A49239FDBAB

Q36498347-497D272B-68EF-4ED0-87A4-D03D4BAC9DE4

Q36498347-4A40E96F-92C2-4F24-A63D-D7F45AB013D3

Q36498347-52CB09E7-6415-4D2B-9F41-EF02C7F452F9

Q36498347-570D6B77-B91D-454E-AA34-21ABB3C6C24F

P304

Q36498347-C0BDE5C0-53E9-4A8C-A993-BEBA73F4A66C

P31

Q36498347-CDDCE293-78A8-4FBD-AF0D-BF8CDCF967FA

P356

Q36498347-86702663-864D-4231-9EB3-AE105E7342BA

P407

Q36498347-34F583F1-5D79-447A-B9D5-716CC1CD23D4

P433

Q36498347-3B38EF40-D687-40B4-8298-016FBB73B902

P478

Q36498347-7875B988-75A8-4874-B8B3-59D5ADF5D104

P577

Q36498347-07C91F0B-2752-4BA0-B8C0-E70A49EAD17C

P5875

Q36498347-21EF06C6-1167-4C2F-98DC-9842424850DD

P698

Q36498347-BD2BA51B-EEFA-40F2-868F-436D91DBA593

P932

Q36498347-40A7F928-4C6D-4F39-8B96-1ACDCA124842

P356

PNAS.1515152113

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Structural basis for m7G recog ...... innate immune receptor RIG-I.

@en

P2093

Abdul G Khan

http://www.w3.org/2001/XMLSchema#string

Anand Ramanathan

http://www.w3.org/2001/XMLSchema#string

Chen Wang

http://www.w3.org/2001/XMLSchema#string

Fuguo Jiang

http://www.w3.org/2001/XMLSchema#string

Joseph Marcotrigiano

http://www.w3.org/2001/XMLSchema#string

Matthew T Miller

http://www.w3.org/2001/XMLSchema#string

Smita S Patel

http://www.w3.org/2001/XMLSchema#string

Swapnil C Devarkar

http://www.w3.org/2001/XMLSchema#string

P2860

Regulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2

Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins

Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.

SF1 and SF2 helicases: family matters

Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I

The Structural Basis of 5′ Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain

Visualizing the Determinants of Viral RNA Recognition by Innate Immune Sensor RIG-I

Structural basis of RNA recognition and activation by innate immune receptor RIG-I

Structural Insights into RNA Recognition by RIG-I

Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA

P304

596-601

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.1515152113

http://www.w3.org/2001/XMLSchema#string

P407

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

113

http://www.w3.org/2001/XMLSchema#string

P577

2016-01-05T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

289494894

http://www.w3.org/2001/XMLSchema#string

P698

26733676

http://www.w3.org/2001/XMLSchema#string

P932

4725518

http://www.w3.org/2001/XMLSchema#string