The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies
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Emerging Role and Therapeutic Implication of Wnt Signaling Pathways in Autoimmune DiseasesWnt-signalling pathways and microRNAs network in carcinogenesis: experimental and bioinformatics approachesOncogenic roles of SMARCB1/INI1 and its deficient tumorsWnt and BMP Signaling Crosstalk in Regulating Dental Stem Cells: Implications in Dental Tissue Engineering.Transition to resistance: An unexpected role of the EMT in cancer chemoresistance.Apigenin-induced lysosomal degradation of β-catenin in Wnt/β-catenin signaling.HIF-1α activates hypoxia-induced BCL-9 expression in human colorectal cancer cellsNoncanonical Wnt signaling plays an important role in modulating canonical Wnt-regulated stemness, proliferation and terminal differentiation of hepatic progenitors.ATP-P2Y2-β-catenin axis promotes cell invasion in breast cancer cellsBone morphogenetic protein 9 (BMP9) induces effective bone formation from reversibly immortalized multipotent adipose-derived (iMAD) mesenchymal stem cells.mir-218-2 promotes glioblastomas growth, invasion and drug resistance by targeting CDC27.Genomic dissection of conserved transcriptional regulation in intestinal epithelial cells.Down-regulation of β-catenin and the associated migration ability by Taiwanin C in arecoline and 4-NQO-induced oral cancer cells via GSK-3β activation.Wnt/β-catenin signaling plays an ever-expanding role in stem cell self-renewal, tumorigenesis and cancer chemoresistance.A central role for cadherin signaling in cancer.Expression/activation of α5β1 integrin is linked to the β-catenin signaling pathway to drive migration in glioma cells.Molecular genetics and targeted therapy of WNT-related human diseases (Review).The effect of EBV on WIF1, NLK, and APC gene methylation and expression in gastric carcinoma and nasopharyngeal cancer.lncRNA H19 mediates BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs) through Notch signaling.Canonical and non-canonical WNT signaling in cancer stem cells and their niches: Cellular heterogeneity, omics reprogramming, targeted therapy and tumor plasticity (Review)Regulation of β-Catenin Phosphorylation by PR55β in Adenoid Cystic Carcinoma.HO1 and Wnt expression is independently regulated in female mice brains following permanent ischemic brain injury.IL-3R-alpha blockade inhibits tumor endothelial cell-derived extracellular vesicle (EV)-mediated vessel formation by targeting the β-catenin pathway.Celecoxib targets breast cancer stem cells by inhibiting the synthesis of prostaglandin E2 and down-regulating the Wnt pathway activity.Antagonism between Hedgehog and Wnt signaling pathways regulates tumorigenicity.CRISPR/Cas9-mediated reversibly immortalized mouse bone marrow stromal stem cells (BMSCs) retain multipotent features of mesenchymal stem cells (MSCs).Wnt Signaling and Its Impact on Mitochondrial and Cell Cycle Dynamics in Pluripotent Stem Cells.Evaluation of YAP signaling in a rat tympanic membrane under a continuous negative pressure load and in human middle ear cholesteatoma.Vemurafenib and trametinib reduce expression of CTGF and IL-8 in V600EBRAF melanoma cells.Effects of SOST Gene Silencing on Proliferation, Apoptosis, Invasion, and Migration of Human Osteosarcoma Cells Through the Wnt/β-Catenin Signaling Pathway.Baicalein suppresses the proliferation of acute T-lymphoblastic leukemia Jurkat cells by inhibiting the Wnt/β-catenin signaling.Chemotherapy-Induced Long Non-coding RNA 1 Promotes Metastasis and Chemo-Resistance of TSCC via the Wnt/β-Catenin Signaling Pathway.Immunological Approaches Towards Cancer and Inflammation: A Cross Talk.Crosstalk Between Peroxisome Proliferator-Activated Receptor Gamma and the Canonical WNT/β-Catenin Pathway in Chronic Inflammation and Oxidative Stress During Carcinogenesis.Editor's Highlight: Identification and Characterization of Teratogenic Chemicals Using Embryonic Stem Cells Isolated From a Wnt/β-Catenin-Reporter Transgenic Mouse Line.Inhibition of the Wnt/β-catenin pathway overcomes resistance to enzalutamide in castration-resistant prostate cancer.Brief report: RRx-001 is a c-Myc inhibitor that targets cancer stem cells.GLI3 knockdown decreases stemness, cell proliferation and invasion in oral squamous cell carcinomaBreast cancer development and progression: Risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesisPhase Ib Results of the Rational Combination of Selumetinib and Cyclosporin A in Advanced Solid Tumors with an Expansion Cohort in Metastatic Colorectal Cancer
P2860
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P2860
The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
The evolving roles of canonica ...... s in targeted cancer therapies
@ast
The evolving roles of canonica ...... s in targeted cancer therapies
@en
type
label
The evolving roles of canonica ...... s in targeted cancer therapies
@ast
The evolving roles of canonica ...... s in targeted cancer therapies
@en
prefLabel
The evolving roles of canonica ...... s in targeted cancer therapies
@ast
The evolving roles of canonica ...... s in targeted cancer therapies
@en
P2093
P2860
P1476
The evolving roles of canonica ...... s in targeted cancer therapies
@en
P2093
Fugui Zhang
Guoxin Nan
Hongmei Zhang
Maryam K Mohammed
Rex C Haydon
Tong-Chuan He
P2860
P2888
P304
P356
10.1038/LABINVEST.2015.144
P50
P577
2015-11-30T00:00:00Z