The canonical Wnt signalling pathway and its APC partner in colon cancer development. - Wikidata - thesis-toulmin - TriplyDB

The canonical Wnt signalling pathway and its APC partner in colon cancer development.

The canonical Wnt signalling pathway and its APC partner in colon cancer development.

http://www.wikidata.org/entity/Q36535617

about

LGR5 is a negative regulator of tumourigenicity, antagonizes Wnt signalling and regulates cell adhesion in colorectal cancer cell lines Down-regulation of frizzled-7 expression decreases survival, invasion and metastatic capabilities of colon cancer cells Activator protein 2alpha suppresses intestinal tumorigenesis in the Apc(min) mouse Transcription factor 7-like 2 polymorphism and colon cancer Selenium and inflammatory bowel disease A common role for various human truncated adenomatous polyposis coli isoforms in the control of beta-catenin activity and cell proliferation Functional comparison of human adenomatous polyposis coli (APC) and APC-like in targeting beta-catenin for degradation different Roles for the axin interactions with the SAMP versus the second twenty amino acid repeat of adenomatous polyposis coli A metabolic switch controls intestinal differentiation downstream of Adenomatous polyposis coli (APC).The intestine-specific transcription factor Cdx2 inhibits beta-catenin/TCF transcriptional activity by disrupting the beta-catenin-TCF protein complex.The catenin family at a glance.The Epigenomics of Embryonic Pathway Signaling in Colorectal Cancer.Novel APC gene mutations associated with protein alteration in diffuse type gastric cancer.Niclosamide is a potential therapeutic for familial adenomatosis polyposis by disrupting Axin-GSK3 interaction.Independent interactions of phosphorylated β-catenin with E-cadherin at cell-cell contacts and APC at cell protrusions.Cancer inflammation and regulatory T cells.Silibinin suppresses growth of human colorectal carcinoma SW480 cells in culture and xenograft through down-regulation of beta-catenin-dependent signaling.Comparative profiling of primary colorectal carcinomas and liver metastases identifies LEF1 as a prognostic biomarker Attenuation of the beta-catenin/TCF4 complex in colorectal cancer cells induces several growth-suppressive microRNAs that target cancer promoting genes.Period 2 mutation accelerates ApcMin/+ tumorigenesis.Polymorphisms in the adenomatous polyposis coli (APC) gene and advanced colorectal adenoma risk Vitamin D and cancer: a review of molecular mechanisms Evolution of network biomarkers from early to late stage bladder cancer samples.Protein kinase D1 attenuates tumorigenesis in colon cancer by modulating β-catenin/T cell factor activity.Inhibition of Tcf-4 induces apoptosis and enhances chemosensitivity of colon cancer cells Rapid induction of colon carcinogenesis in CYP1A-humanized mice by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate.Myofibroblast-derived SFRP1 as potential inhibitor of colorectal carcinoma field effect Silibinin exerts sustained growth suppressive effect against human colon carcinoma SW480 xenograft by targeting multiple signaling molecules.Differential expression of IL-17, 22 and 23 in the progression of colorectal cancer in patients with K-ras mutation: Ras signal inhibition and crosstalk with GM-CSF and IFN-γ Antihelminth compound niclosamide downregulates Wnt signaling and elicits antitumor responses in tumors with activating APC mutations.Synthesis, Structure-Activity Relationship, and Mechanistic Investigation of Lithocholic Acid Amphiphiles for Colon Cancer Therapy.Prevalence and molecular characterisation of the sessile serrated adenoma in a subset of the Chinese population.Retained cell–cell adhesion in serrated neoplastic pathway as opposed to conventional colorectal adenomas CD4+ lymphocytes modulate prostate cancer progression in mice.Mouse Crumbs3 sustains epithelial tissue morphogenesis in vivo Analysis of APC and IGFBP7 promoter gene methylation in Swedish and Vietnamese colorectal cancer patients.Analysis of molecular aberrations of Wnt pathway gladiators in colorectal cancer in the Kashmiri population.Analysis of bacteria from intestinal tract of FAP patients for the presence of APC-like sequences Inflammation and colorectal cancer: colitis-associated neoplasia.Frizzled-7 as a potential therapeutic target in colorectal cancer.

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P2860

The canonical Wnt signalling pathway and its APC partner in colon cancer development.

http://www.wikidata.org/entity/Q36535617

description

2006 nî lūn-bûn

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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2006年论文

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2006年论文

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name

The canonical Wnt signalling pathway and its APC partner in colon cancer development.

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The canonical Wnt signalling pathway and its APC partner in colon cancer development.

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type

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The canonical Wnt signalling pathway and its APC partner in colon cancer development.

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The canonical Wnt signalling pathway and its APC partner in colon cancer development.

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The canonical Wnt signalling pathway and its APC partner in colon cancer development.

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The canonical Wnt signalling pathway and its APC partner in colon cancer development.

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The canonical Wnt signalling pathway and its APC partner in colon cancer development.

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Jean Schneikert

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Jürgen Behrens

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P2860

Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling

Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation

A role for the Adenomatous Polyposis Coli protein in chromosome segregation

The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin

Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development

Identification of c-MYC as a target of the APC pathway

Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coli

Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer

Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells

Secretion of Wnt ligands requires Evi, a conserved transmembrane protein

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417-425

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