The Niemann-Pick C1 gene is downregulated by feedback inhibition of the SREBP pathway in human fibroblasts.
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Loss of Niemann Pick type C proteins 1 and 2 greatly enhances HIV infectivity and is associated with accumulation of HIV Gag and cholesterol in late endosomes/lysosomesGenetic perspective on the role of the autophagy-lysosome pathway in Parkinson diseaseMolecular pathways for intracellular cholesterol accumulation: common pathogenic mechanisms in Niemann-Pick disease Type C and cystic fibrosisThe Niemann-Pick C1 and caveolin-1 proteins interact to modulate efflux of low density lipoprotein-derived cholesterol from late endocytic compartments.Npc1 haploinsufficiency promotes weight gain and metabolic features associated with insulin resistance.Lysosomal acid lipase: at the crossroads of normal and atherogenic cholesterol metabolismGene-diet interactions in childhood obesity.The Niemann-Pick C1 gene is downregulated in livers of C57BL/6J mice by dietary fatty acids, but not dietary cholesterol, through feedback inhibition of the SREBP pathway.The cytosolic adaptor AP-1A is essential for the trafficking and function of Niemann-Pick type C proteinsEvaluation of common genetic variants identified by GWAS for early onset and morbid obesity in population-based samples.Niemann-Pick C2 (NPC2) and intracellular cholesterol trafficking.Characterization of cholesterol homeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts reveals a Niemann-Pick disease type C-like phenotype with enhanced lysosomal Ca2+ storage.Cholesterol supply and SREBPs modulate transcription of the Niemann-Pick C-1 gene in steroidogenic tissues.The Niemann-Pick C1 gene interacts with a high-fat diet to promote weight gain through differential regulation of central energy metabolism pathways.
P2860
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P2860
The Niemann-Pick C1 gene is downregulated by feedback inhibition of the SREBP pathway in human fibroblasts.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The Niemann-Pick C1 gene is do ...... pathway in human fibroblasts.
@ast
The Niemann-Pick C1 gene is do ...... pathway in human fibroblasts.
@en
type
label
The Niemann-Pick C1 gene is do ...... pathway in human fibroblasts.
@ast
The Niemann-Pick C1 gene is do ...... pathway in human fibroblasts.
@en
prefLabel
The Niemann-Pick C1 gene is do ...... pathway in human fibroblasts.
@ast
The Niemann-Pick C1 gene is do ...... pathway in human fibroblasts.
@en
P2093
P2860
P1476
The Niemann-Pick C1 gene is do ...... pathway in human fibroblasts.
@en
P2093
Bruce D Murphy
David Jelinek
Gordon A Francis
William S Garver
P2860
P304
P356
10.1194/JLR.M700555-JLR200
P577
2008-02-13T00:00:00Z