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Metastasis-associated in colon cancer-1 in gastric cancer: Beyond metastasisFluorescence Polarization Screening Assays for Small Molecule Allosteric Modulators of ABL Kinase FunctionMolecular Determinants Underlying Binding Specificities of the ABL Kinase Inhibitors: Combining Alanine Scanning of Binding Hot Spots with Network Analysis of Residue Interactions and CoevolutionParallel Chemical Protein Synthesis on a Surface Enables the Rapid Analysis of the Phosphoregulation of SH3 Domains.Angiotensin II down-regulates nephrin-Akt signaling and induces podocyte injury: roleof c-Abl.The NESH/Abi-3-based WAVE2 complex is functionally distinct from the Abi-1-based WAVE2 complex.Defying c-Abl signaling circuits through small allosteric compounds.A Discovery Strategy for Selective Inhibitors of c-Src in Complex with the Focal Adhesion Kinase SH3/SH2-binding Region.Exploring Molecular Mechanisms of Paradoxical Activation in the BRAF Kinase Dimers: Atomistic Simulations of Conformational Dynamics and Modeling of Allosteric Communication Networks and Signaling Pathways.The structural basis for cancer treatment decisions.Response to imatinib as a function of target kinase expression in recurrent glioblastoma.Computational study of the "DFG-flip" conformational transition in c-Abl and c-Src tyrosine kinases.Combined inhibition of EGFR and c-ABL suppresses the growth of triple-negative breast cancer growth through inhibition of HOTAIR.Identification of Entry Factors Involved in Hepatitis C Virus Infection Based on Host-Mimicking Short Linear Motifs.The Emerging Role of ABL Kinases in Solid Tumors.Phosphorylation of Tip60 Tyrosine 327 by Abl Kinase Inhibits HAT Activity through Association with FE65.A development that may evolve into a revolution in medicine: mRNA as the basis for novel, nucleotide-based vaccines and drugsBcr-Abl tyrosine kinase inhibitors: a patent review.Natural products against hematological malignancies and identification of their targets.Small-world networks of residue interactions in the Abl kinase complexes with cancer drugs: topology of allosteric communication pathways can determine drug resistance effects.Global connectivity of hub residues in Oncoprotein structures encodes genetic factors dictating personalized drug response to targeted Cancer therapy.Role and regulation of Abelson tyrosine kinase in Crk-associated substrate/profilin-1 interaction and airway smooth muscle contraction.Atomic view of the energy landscape in the allosteric regulation of Abl kinase.Identification of natural inhibitors of Bcr-Abl for the treatment of chronic myeloid leukemia.Role of Non Receptor Tyrosine Kinases in Hematological Malignances and its Targeting by Natural Products.Chronic myeloid leukemia: the paradigm of targeting oncogenic tyrosine kinase signaling and counteracting resistance for successful cancer therapy.Role of c-Abl and nephrin in podocyte cytoskeletal remodeling induced by angiotensin II.Computational dissection of allosteric inhibition of the SH2 domain of Bcr-Abl kinase by the monobody inhibitor AS25.Protective Effects of Silymarin and Silibinin against DNA Damage in Human Blood Cells
P2860
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P2860
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Structure and dynamic regulation of Abl kinases.
@ast
Structure and dynamic regulation of Abl kinases.
@en
type
label
Structure and dynamic regulation of Abl kinases.
@ast
Structure and dynamic regulation of Abl kinases.
@en
prefLabel
Structure and dynamic regulation of Abl kinases.
@ast
Structure and dynamic regulation of Abl kinases.
@en
P2093
P2860
P356
P1476
Structure and dynamic regulation of Abl kinases.
@en
P2093
Roxana E Iacob
Shoghag Panjarian
Shugui Chen
Thomas E Smithgall
P2860
P304
P356
10.1074/JBC.R112.438382
P407
P577
2013-01-11T00:00:00Z