Frequent and variable cytotoxic-T-lymphocyte escape-associated fitness costs in the human immunodeficiency virus type 1 subtype B Gag proteins.
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Role of HLA Adaptation in HIV EvolutionBottlenecks in HIV-1 transmission: insights from the study of founder virusesComposite Sequence-Structure Stability Models as Screening Tools for Identifying Vulnerable Targets for HIV Drug and Vaccine Development.Reversion and T cell escape mutations compensate the fitness loss of a CD8+ T cell escape mutant in their cognate transmitted/founder virusImpact of HLA selection pressure on HIV fitness at a population level in Mexico and Barbados.HIV control is mediated in part by CD8+ T-cell targeting of specific epitopes.Impact of HLA-driven HIV adaptation on virulence in populations of high HIV seroprevalence.Transmitted virus fitness and host T cell responses collectively define divergent infection outcomes in two HIV-1 recipients.HIV transmission. Selection bias at the heterosexual HIV-1 transmission bottleneck.Nef-specific CD8+ T cell responses contribute to HIV-1 immune control.Identification of effective subdominant anti-HIV-1 CD8+ T cells within entire post-infection and post-vaccination immune responses.A restriction enzyme based cloning method to assess the in vitro replication capacity of HIV-1 subtype C Gag-MJ4 chimeric viruses.The route of HIV escape from immune response targeting multiple sites is determined by the cost-benefit tradeoff of escape mutations.Discordant Impact of HLA on Viral Replicative Capacity and Disease Progression in Pediatric and Adult HIV Infection.Global Database-Driven Assessment of HIV-1 Adaptation to the Immune Repertoires of Human PopulationsFitness-Balanced Escape Determines Resolution of Dynamic Founder Virus Escape Processes in HIV-1 Infection.The Breadth of Expandable Memory CD8+ T Cells Inversely Correlates with Residual Viral Loads in HIV Elite Controllers.Consequences of HLA-B*13-Associated Escape Mutations on HIV-1 Replication and Nef Function.Relative resistance of HIV-1 founder viruses to control by interferon-alpha.Increased sequence coverage through combined targeting of variant and conserved epitopes correlates with control of HIV replication.Differential escape patterns within the dominant HLA-B*57:03-restricted HIV Gag epitope reflect distinct clade-specific functional constraints.Tertiary mutations stabilize CD8+ T lymphocyte escape-associated compensatory mutations following transmission of simian immunodeficiency virusRole of Gag mutations in PI resistance in the Swiss HIV cohort study: bystanders or contributors?HLA-B*14:02-Restricted Env-Specific CD8+ T-Cell Activity Has Highly Potent Antiviral Efficacy Associated with Immune Control of HIV Infection.Adaptive HIV-1 evolutionary trajectories are constrained by protein stability.HIV-1 epitopes presented by MHC class I types associated with superior immune containment of viremia have highly constrained fitness landscapes.Role of HIV-specific CD8(+) T cells in pediatric HIV cure strategies after widespread early viral escape.In vivo virulence of MHC-adapted AIDS virus serially-passaged through MHC-mismatched hosts.Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes.High-Resolution Sequencing of Viral Populations During Early SIV Infection Reveals Evolutionary Strategies for Rapid Escape from Emerging Env-Specific Antibody Responses.Weaker HLA Footprints on HIV in the Unique and Highly Genetically Admixed Host Population of Mexico.
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Frequent and variable cytotoxic-T-lymphocyte escape-associated fitness costs in the human immunodeficiency virus type 1 subtype B Gag proteins.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Frequent and variable cytotoxi ...... type 1 subtype B Gag proteins.
@ast
Frequent and variable cytotoxi ...... type 1 subtype B Gag proteins.
@en
type
label
Frequent and variable cytotoxi ...... type 1 subtype B Gag proteins.
@ast
Frequent and variable cytotoxi ...... type 1 subtype B Gag proteins.
@en
prefLabel
Frequent and variable cytotoxi ...... type 1 subtype B Gag proteins.
@ast
Frequent and variable cytotoxi ...... type 1 subtype B Gag proteins.
@en
P2093
P2860
P356
P1433
P1476
Frequent and variable cytotoxi ...... type 1 subtype B Gag proteins.
@en
P2093
Aaron Seese
Arne Schneidewind
Christian L Boutwell
David Heckerman
Jonathan M Carlson
Karen A Power
Tien-Ho Lin
Todd M Allen
Yanhua Tang
P2860
P304
P356
10.1128/JVI.03233-12
P407
P577
2013-01-30T00:00:00Z