Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells
about
Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNAMultidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogsThe human multidrug resistance-associated protein functionally complements the yeast cadmium resistance factor 1.pABC11 (also known as MOAT-C and MRP5), a member of the ABC family of proteins, has anion transporter activity but does not confer multidrug resistance when overexpressed in human embryonic kidney 293 cellsMultidrug-resistance P-glycoprotein (MDR1) secretes platelet-activating factorInhibitory effect of the reversal agents V-104, GF120918 and Pluronic L61 on MDR1 Pgp-, MRP1- and MRP2-mediated transportMechanism of sensitization of MDR cancer cells by Pluronic block copolymers: Selective energy depletionEnvironmental xenobiotics and the antihormones cyproterone acetate and spironolactone use the nuclear hormone pregnenolone X receptor to activate the CYP3A23 hormone response elementHomologues of the human multidrug resistance genes MRP and MDR contribute to heavy metal resistance in the soil nematode Caenorhabditis elegansMultidrug resistance-associated protein 1 (MRP1/ABCC1) polymorphism: from discovery to clinical applicationLocalization and functional characterization of the rat Oatp4c1 transporter in an in vitro cell system and rat tissuesAccumulation and oriented transport of ampicillin in Caco-2 cells from its pivaloyloxymethylester prodrug, pivampicillin.Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier.Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier.A family of drug transporters: the multidrug resistance-associated proteins.Differences in the expression of endogenous efflux transporters in MDR1-transfected versus wildtype cell lines affect P-glycoprotein mediated drug transport.Intermediate structural states involved in MRP1-mediated drug transport. Role of glutathione.Is Ciprofloxacin a Substrate of P-glycoprotein?Active transport of the angiotensin-II antagonist losartan and its main metabolite EXP 3174 across MDCK-MDR1 and caco-2 cell monolayers.ABC transporters in multi-drug resistance and ADME-Tox of small molecule tyrosine kinase inhibitors.Drug transporters, the blood-testis barrier, and spermatogenesisThe MRP family of drug efflux pumps.Molecular and cellular physiology of renal organic cation and anion transport.Tyrosine kinase inhibitors as modulators of ABC transporter-mediated drug resistance.Molecular and ionic mimicry and the transport of toxic metals.Opioid analgesics and P-glycoprotein efflux transporters: a potential systems-level contribution to analgesic tolerance.Improving cancer chemotherapy with modulators of ABC drug transporters.Phorbol 12-myristate 13-acetate inhibits P-glycoprotein-mediated efflux of digoxin in MDCKII-MDR1 and Caco-2 cell monolayer models.Role of efflux pumps and metabolising enzymes in drug delivery.Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules against drug-induced damage.Modulation of the ATPase and transport activities of broad-acting multidrug resistance factor ABCC10 (MRP7).Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins.Sulindac sulfide selectively increases sensitivity of ABCC1 expressing tumor cells to doxorubicin and glutathione depletionDevelopment of inhibitors of ATP-binding cassette drug transporters: present status and challenges.Advancement of structure-activity relationship of multidrug resistance-associated protein 2 interactions.The pathogenesis of cystinosis: mechanisms beyond cystine accumulation.Multidrug resistance associated proteins in multidrug resistance.Fluoroquinolone disposition: identification of the contribution of renal secretory and reabsorptive drug transporters.Importance of ABCC1 for cancer therapy and prognosis.Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export.
P2860
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P2860
Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Basolateral localization and e ...... in polarized pig kidney cells
@ast
Basolateral localization and e ...... in polarized pig kidney cells
@en
type
label
Basolateral localization and e ...... in polarized pig kidney cells
@ast
Basolateral localization and e ...... in polarized pig kidney cells
@en
prefLabel
Basolateral localization and e ...... in polarized pig kidney cells
@ast
Basolateral localization and e ...... in polarized pig kidney cells
@en
P2093
P2860
P356
P1476
Basolateral localization and e ...... in polarized pig kidney cells
@en
P2093
Oude Elferink RP
Schinkel AH
van Deemter L
P2860
P304
P356
10.1172/JCI118535
P407
P577
1996-03-01T00:00:00Z